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GAD65-specific autoantibodies enhance the presentation of an immunodominant T-cell epitope from GAD65

GAD65 autoantibodies (GAD65Ab) are highly prevalent in type 1 diabetes, but their functional role in the pathogenesis of the disease and their relationship to T-cell reactivity to GAD65 is still unclear. We tested the hypothesis that GAD65Ab modulate presentation of GAD65 to T-cells. T-cell hybridoma T33.1, which recognizes the GAD65 274-286 epitope in the context of HLA-DRB1*0401, was incubated w

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The aim of present study was to arrange an experimental rabbit model for IgA-nephropathy. To this purpose, an approach was attempted which was previously successfully applied in rabbits, aiming for induction of post-streptococcal glomerulonephritis (PSGN). To induce the nephropathy, we used two Streptococcus pyogenes strains of M4 and M60 serotypes which showed differential IgA-binding capacity me

Molecular mapping of epitopes for interaction of HIV-1 as well as natural ligands with the chemokine receptors, CCR5 and CXCR4.

OBJECTIVE: Mapping coreceptor epitopes used by the prototypic R5 and X4 strains, HIV-1BaL and HIV-1IIIB, in comparison with epitopes involved in the activation and signaling induced by the natural ligands, RANTES and SDF-1beta. DESIGN: Receptor hybrids between CCR5 and CXCR4 were constructed. METHODS: Using single-overlap and extension PCR, increasing portions of CCR5 were replaced with correspond

Serum Complement Activation by C4BP-IgM Fusion Protein Can Restore Susceptibility to Antibiotics in Neisseria gonorrhoeae

Neisseria gonorrhoeae is the etiological agent of gonorrhea, the second most common bacterial sexually transmitted infection worldwide. Reproductive sequelae of gonorrhea include infertility, ectopic pregnancy and chronic pelvic pain. Most antibiotics currently in clinical use have been rendered ineffective due to the rapid spread of antimicrobial resistance among gonococci. The developmental pipe

Production and Functional Characterization of Der p 1-Specific Human Recombinant IgE

Ny forskning bidrar till ökad förståelse av allergiska reaktioner Allergi har ökat dramatiskt under de senaste åren. Det är därför högst väsentligt att få ökad kunskap om hur beståndsdelarna i immunförsvaret hos allergiska personer samspelar. Förekomsten av allergi har kommit att öka dramatiskt under de senaste åren och har blivit ett betydande problem för folkhälsan. Allergi drabbar en så stor dThe prevalence of allergic disease is continuing to increase worldwide, and it has even become a major concern in public health. Allergic reactions are developed to otherwise harmless substances and may be both life-threatening as well as discomforting for patients in their daily life. Therefore, a more detailed knowledge about how antibodies interact with allergens and effector cells in allergic

Sgkri utbildningsplan beslut1

Utbildningsplan Kandidatprogram i kriminologi Samhällsvetenskapliga fakulteten SGKRI, Kandidatprogram i kriminologi, 180 högskolepoäng Bachelor of Science Programme in Criminology, 180 credits Program utan akademiska förkunskapskrav och med slutlig examen på grundnivå / First cycle degree programme not requiring previous university study Beslutsuppgifter Utbildningsplanen är fastställd av Prodekan

https://www.soclaw.lu.se/sites/soclaw.lu.se/files/sgkri_utbildningsplan_beslut1.pdf - 2026-05-29

Samtida internationell scenkonst - en orientering

Fristående kurs på distans, 7.5 högskolepoäng Vill du möta scenkonstnärer och teatrar i olika länder, inspireras av samtida internationell scenkonst, samt bilda dig en uppfattning om estetiska strömningar och skapandets varierande förutsättningar? Kom då med på denna onlineorientering och berika din förståelse av världen genom scenkonst. Under kursen görs flera live-filmade besök på scenkonst-orga

https://www.thm.lu.se/samtida-internationell-scenkonst-en-orientering - 2026-05-27

Hungry Eyes

Friday, at 19:00 – Performance "Immanuel, Immanuel!" by Hungry Eyes Hungry Eyes is a Danish–Swedish performance collective founded by Theatre Academy alumni Dina Viksten Abrahamson, Ida Østman, Mie Kristensen and Olivia Klang. At IAC, they present their second work Immanuel, Immanuel! – a conceptual exploration of the choir as form and method. A choir without choral singing, an essayistic, hopeful

https://www.iac.lu.se/hungry-eyes - 2026-05-27

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Je m'apelle XX! Ah bon, en tout cas c'est ma pseudonyme. Je suis une fille très joyeux de ma vie, mes copains et mon famille. Maintenant la soleil brille et ca me fais de très bonne humeur! Je vais maintenant te raconter une histoire (interessant) assez détaillé.. J'ai de cheveux très blonde et des yeux bleu, ou peut-être vert? Je ne sais pas actuallement. Mais pour concentrer ma l'air dans deux m

https://projekt.ht.lu.se/fileadmin/user_upload/project/cefle/textes/le_sous-corpus_longitudinal/dagmar/Texte_4.txt - 2026-05-28

Litteraturlista för

Litteraturlista för 2 LITTERATURLISTA OSHA02: Japans historia (15 hp) History of Japan (15 credits) Fastställd av styrelsen för sektion 6 2025-12-04 Japans äldre historia Böcker och bokutdrag: Benesch, Oleg (2014). Inventing the Way of the Samurai: Nationalism, Internationalism and Bushido in Modern Japan . Oxford: Oxford University Press, s. 1(33. (33 sidor) [Tillgänglig som e- bok] De Bary, WM.

https://www.sol.lu.se/media/utbildning/dokument/kurser/OSHA02/20261/OSHA02_LItteraturlista_vt26.doc - 2026-05-28

Roma and Travellers in six countries - ROMA AND TRAVELLERS SURVEY

Roma and Travellers in six countries - ROMA AND TRAVELLERS SURVEY R O M A A N D T R A V EL LE R S SU R V EY ROMA AND TRAVELLERS IN SIX COUNTRIES ― © European Union Agency for Fundamental Rights, 2020 Reproduction is authorised provided the source is acknowledged. For any use or reproduction of photos or other material that is not under the European Union Agency for Fundamental Rights copyright, pe

https://rwi.lu.se/wp-content/uploads/2022/10/fra-2020-roma-travellers-six-countries_en.pdf - 2026-05-29

Myten om republikanismen: En dekonstruktion av dagens franska demokratiideal

This paper is a critique of the hegemonic democracy ideal in France today, the myth of the Republic. Based on critical theory, the paper also contains a normative attempt giving the chance to subaltern groups to tell their, less often heard, version of the "truth". The theoretical foundation is the ontological narrative perspective, where identities and actions are understood as being c

Hekn14 provisional schedule

1 SPRING 2020 POLITICAL ECOLOGY, CRISIS AND IDENTITY (HEKN14 // Provisional) TEACHERS: Mads Barbesgaard (MB) [course coordinator] – mads.barbesgaard.2321@keg.lu.se Amr Ahmed (AA) -- amr.ahmed@keg.lu.se Mariko Takedomi Karlsson (MKT) – mariko.takedomi_karlsson@hek.lu.se Mathilde Martin (MM) -- mathilde.martin@keg.lu.se Rooms: F=Flygeln (first floor), R=Rio (fourth floor), M=Malmö (fourth floor), V=

https://www.keg.lu.se/en/sites/keg.lu.se.en/files/hekn14_provisional_schedule.pdf - 2026-05-29

Publication in j neurochem

REV_ISS_WEB_jnc_6650_113-4 836..847 *MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College, London, UK Wallenberg Neuroscience Centre, Lund University, Lund, Sweden The midbrain dopaminergic (mDA) neurons are the largest assembly of dopaminergic neurons in the central nervous system and play an important role in motor control, reward, addiction and cognition (Bjorklund and Lindvall 1

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_j_neurochem.pdf - 2026-05-29

Microsoft Word - Sigurdur_Ingvarsson.doc

Microsoft Word - Sigurdur_Ingvarsson.doc Signalling mechanisms in B cell differentiation Studies on specific human immune responses in vitro Sigurdur Ingvarsson Department of Immunotechnology Lund University Lund, Sweden 2 1998 3 © 1998 Sigurdur Ingvarsson ISBN 91-628-3004-X 4 Printed in Sweden by KFS in Lund 5 Inngangur á íslensku 6 Acknowledgements 7 Contents Inngangur á íslensku 5 Acknowledgeme

https://www.immun.lth.se/fileadmin/immun/Avhandlingar/Sigurdur_Ingvarsson.pdf - 2026-05-28