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A breakpoint map of recurrent chromosomal rearrangements in human neoplasia

Cytogenetic studies over the past few decades have revealed clonal chromosomal aberrations in almost 27,000 human neoplasms. Many of these neoplasia-associated chromosomal abnormalities have been characterised at the molecular level, revealing previously unknown genes that are closely associated with the tumorigenic process. Information on chromosome changes in neoplasia is growing rapidly, making

Wintering diving duck populations in the Öresund, Southern Sweden, in relation to available food Resources.

Intensive surveys of staging and wintering diving ducks in the Öresund area,southern Sweden, were undertaken during the winters 1995/96, 1996/97 and1997/98 as a part of the Environmental Impact Assessment (EIA) related to theestablishment of a Fixed Link (bridge–tunnel–artificial island) between Swedenand Denmark. Monitoring of the benthic fauna made it possible to compare thecalculated food requi

Holographic imaging with a hard x-ray nanoprobe : Ptychographic versus conventional phase retrieval

We have performed near-field x-ray imaging with simultaneous object and probe reconstruction. By an advanced ptychographic algorithm based on longitudinal and lateral translations, full-field images of nanoscale objects are reconstructed with quantitative contrast values, along with the extended wavefronts used to illuminate the objects. The imaging scheme makes idealizing assumptions on the probe

Possible association of a novel missense mutation A6375G in the mitochondrial cytochrome C oxidase I gene with asthenospermia in the Tunisian population

Cytochrome c oxidase encoded by multiple mitochondrial genes (COXI, COXII, and COXIII) and nuclear genes is an essential component of the mitochondrial respiratory chain that catalyzes the reduction of molecular oxygen by reduced cytochrome c. Subunits COXI and COXII of cytochrome c oxidase are known to play the most essential role in proton pumping and electron transfer. In this study we screened

Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016 : a systematic analysis for the Global Burden of Disease Study 2016

BACKGROUND: Monitoring levels and trends in premature mortality is crucial to understanding how societies can address prominent sources of early death. The Global Burden of Disease 2016 Study (GBD 2016) provides a comprehensive assessment of cause-specific mortality for 264 causes in 195 locations from 1980 to 2016. This assessment includes evaluation of the expected epidemiological transition wit

Bacillus subtilis CcdA defective mutants are blocked in a late step of cytochrome c biogenesis

Cytochromes of the c type contain covalently bound heme. In bacteria, they are located on the outside of the cytoplasmic membrane. Cytochrome c synthesis involves export of heme and apocytochrome across the cytoplasmic membrane followed by ligation of heme to the polypeptide. Using radioactive protoheme IX produced in Escherichia coli, we show that Bacillus subtilis can use heme from the growth me

Intraoperative fall in plasma levels of intact parathyroid hormone after removal of one enlarged parathyroid gland in hyperparathyroid patients

Plasma levels of intact parathyroid hormone (PTH) were measured intraoperatively before and after removal of one enlarged gland in 20 hyperparathyroid patients. In 13 patients with a single parathyroid adenoma, plasma levels of intact PTH-(1-84) had declined at 15 min after removal of the adenoma by 86.5 +/- 4.4% of baseline in the antecubital vein and by 85.6 +/- 4.2% in the ipsilateral internal

Lower spatial QRS-T angle rules out sustained ventricular arrhythmias in children with hypertrophic cardiomyopathy

Introduction: The spatial peaks QRS-T angle accurately distinguishes children with hypertrophic cardiomyopathy from their healthy counterparts. The spatial peaks QRS-T angle is also useful in risk stratification for ventricular arrhythmias. We hypothesised that the spatial peaks QRS-T angle would be useful for the prediction of ventricular arrhythmias in hypertrophic cardiomyopathy patients under

Climate Change observations into Hydropower in Mozambique

Hydropower is a renewable energy that expected to be affected by persistent climate change in Mozambique. Variability of climate e.g. temperature and precipitation will contributors to future shortage of energy from renewable energy production especially for hydropower and biomass. This research reviews the impacts of climate change on the productions of hydropower in Mozambique. Furthermore, a st

Identification of Iridoid Glucoside Transporters in Catharanthus roseus

Monoterpenoid indole alkaloids (MIAs) are plant defense compounds and high-value pharmaceuticals. Biosynthesis of the universal MIA precursor, secologanin, is organized between internal phloem-associated parenchyma (IPAP) and epidermis cells. Transporters for intercellular transport of proposed mobile pathway intermediates have remained elusive. Screening of an Arabidopsis thaliana transporter lib

Egendomsskydd och miljöskydd - En balansering av intressen

Syftet med denna kandidatuppsats har varit att redogöra för förhållandet mellan egendomsskydd och miljöskydd i den svenska rätten. Vidare en analys av hur den svenska lagstiftningen balanserar dessa intresse. Egendomsskydd är en grundrättighet som återfinns i Europakonventionen och i svensk rätt. Rätten till skydd av egendom stadgas i första tilläggsprotokollet till Europakonventionen i första aThe purpose of this bachelor thesis has been to account for the relationship between property protection and environmental protection in Swedish law. Furthermore, to give an analysis of how Swedish legislation balances these interests. Property protection is a fundamental right that can be found in the European Convention on Human Rights and in Swedish law. The right to protection of one’s posse

Prissättning av företrädesemissioner - Vilka variabler påverkar rabatten på emissionspriset?

Syftet av denna studie är analysera ett antal tänkbara faktorer och huruvida dessa har en inverkan på den rabatt som sätts vid en nyemission i Sverige. Vidare avser studien även att besvara hur stor rabatten i genomsnitt är. Resultaten visar att faktorerna börsvärde, erbjudandets relativa storlek, rådgivarens ranking, Price to Book samt andelen av erbjudandet som är garanterat eller på annat sätt

Efficient Estimation of Decaying Sinusoids with Application in NMR Spectroscopy

In this thesis, the Wideband Sparse Exponential Mode Analysis (WSEMA) estimator is introduced. It combines two recently developed techniques, the wideband dictionary and the Sparse Exponential Mode Analysis (SEMA) to make for an efficient estimator. WSEMA estimates the parameters of decaying sinusoids, without a priori-information about the number of modes present in the signal. WSEMA works with a

The role of social capital in resilience against poverty

This thesis captures the effect of social capital measured as social and institutional trust on a reduction of absolute poverty. The indicators of social capital are captured through the construction of a database of subjective well-being measures. Poverty is indicated using the Watt’s index which measures the mean proportionate poverty gap for those living under the extreme poverty line of $1.90

Spatial Vision in Bombus terrestris.

Bombus terrestris is one of the most commonly used insect models to investigate visually guided behavior and spatial vision in particular. Two fundamental measures of spatial vision are spatial resolution and contrast sensitivity. In this study, we report the threshold of spatial resolution in B. terrestris and characterize the contrast sensitivity function of the bumblebee visual system for a dua