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Relationship Between Ljungan Virus Antibodies, HLA-DQ8, and Insulin Autoantibodies in Newly Diagnosed Type 1 Diabetes Children

Environmental factors, including viral infections, may explain an increasing and fluctuating incidence of childhood type 1 diabetes (T1D). Ljungan virus (LV) isolated from bank voles have been implicated, but it is unclear whether LV contributes to islet autoimmunity, progression to clinical onset, or both, of T1D. The aim was to test whether LV antibodies (LVAb) were related to HLA-DQ and islet a

Accuracy and precision in super-resolution MRI : Enabling spherical tensor diffusion encoding at ultra-high b-values and high resolution

Diffusion MRI (dMRI) can probe the tissue microstructure but suffers from low signal-to-noise ratio (SNR) whenever high resolution is combined with high diffusion encoding strengths. Low SNR leads to poor precision as well as poor accuracy of the diffusion-weighted signal; the latter is caused by the rectified noise floor and can be observed as a positive bias in magnitude signal. Super-resolution

Seasonal distribution of sperm whales in the High Arctic revealed by multi-year passive acoustic monitoring

The sperm whale (Physeter macrocephalus) is a cosmopolitan species with a broad distribution that ranges from the tropics to the poles. Males are known to migrate between nutrient-rich high latitude waters and low latitude breeding grounds. In the North Atlantic, large males are found up to the southern limits of the ice edge. However, their seasonal distribution patterns remain poorly known in th

Hyper-velocity stars from globular clusters hosting intermediate-mass black holes

In 1988 Hills proposed that stars can gain velocities above 500 km s−1 if they are in a stellar binary which gets disrupted by a super massive black hole (SMBH). One of the stars would get trapped in an elliptical orbit around the SMBH while the other gets ejected and obtains a relatively high velocity. Normally stars within galaxies have low peculiar velocities but stars ejected with velocities o

Rättvisa – ett lotteri med höga insatser? - Om betydelsen av åklagares åtalsprövning för målsägandens förutsebara tillgång till upprättelse

Brotten vållande till kroppsskada eller sjukdom, förtal, förolämpning och egenmäktighet med barn är alla brott mot person för vilka de brottsutredande myndigheterna enbart får fatta lagföringsbeslut om åtal kan anses påkallat ur allmän synpunkt. Begränsningen, som i vissa fall enbart aktualiseras om målsäganden angivit brottet till åtal, innebär att myndigheterna inte får hantera alla fall även omThe offences causing bodily injury or illness, defamation, insulting behaviour and arbitrary conduct concerning a child are offences against the person to which the investigating authorities can take conviction decisions only if prosecution is called for in the public interest. The limitation, which in some cases is applicable only if the plaintiff has reported an offence for prosecution, means th

Antikorruptionsförebyggande tredjepartsbesiktning och GDPR

Tredjepartsbesiktning innebär att blivande eller befintliga affärspartners undersöks i syfte att säkerställa att verksamhetsutövarens verksamhetsled utgör en låg risk för korruption, vilket i vissa länder krävs genom lag. Faktorer som i regel anses som varningsflaggor i riskbedömningen inför en affärstransaktion är till exempel om en affärspartner har dömts för något brott av korruptiv karaktär elThird party due diligence is an investigation of prospective or existing business partners in order to ensure a low risk of corruption. In certain countries such an investigation is required by law. Factors to consider in the risk assessment are for example whether a potential or existing business partner has been convicted of any corruption related crime or is associated with political circles. S

Regulation of HPV16 splice sites located in the E6/E7 oncogene coding region

Kan cellers proteiner bota HPV- sjukdomar? Livmoderhalscancer är en av de vanligaste cancersjukdomarna som drabbar kvinnor världen över. Varje år, diagnostiseras ungefär 500 000 kvinnor och 270 000 dör i sjukdomen, varav de flesta dödsfallen sker i utvecklingsländer. Livmoderhalscancer orsakas av det vanligt förekommande viruset humant papillomvirus (HPV) och för att hitta bättre behandling mot sHuman papillomaviruses (HPVs) are small DNA viruses that have evolved over millions of years and are well-adapted to humans. Persistent infections with HPVs, can result in cancer development. There are over 200 different HPV types that can be divided into high- and low risk types based on their ability to cause cancer. HPV16 is the most common high- risk type that accounts for more than 50 % of al

OCEAN ACIDIFICATION

Ocean acidification is a consequence of the anthropogenic release of carbon dioxide (CO2) to the atmosphere. When CO2 is dissolved in water it affects the composition of ions and lowers the pH of the water. As the partial CO2 pressure in the atmosphere increases a new balance is reached with the surface waters which causes the pH of the surface oceans to decrease. For small shallow seas this effec

Analysis and Measurements of Vehicle Door Structural Dynamic Response

In order to reduce lead time and cost in the product development of vehicles more development will be made virtually. However, the predictability capability of simulation models is questioned and the simulation models need to be correlated versus hardware measurements and modeling techniques improved. As part of the process of vehicle system model capability improvements the main objective of thi

Brandteknisk Riskvärdering av Dramaten - Kungliga Dramatiska Teatern i Stockholm

Denna rapport är skriven inom kursen ”VBRN70 - Brandteknisk riskvärdering” vid Lunds Tekniska Högskola. Rapporten omfattar en brand- och utrymningsanalys av Kungliga Dramatiska Teatern i Stockholm med fokus på personsäkerhet. Analysen inleddes med ett platsbesök för att få bättre kännedom om objektet. Utifrån observationer från platsbesöket och tillgänglig statistik identifierades därefter flertaThis report is a part of the course ”VBRN70 - Brandteknisk riskvärdering” given by Lund University of Technology. The report presents a fire and risk evaluation of the Royal Dramatical Theatre in Stockholm with focus on the safety of people in the building. The analysis started with a site visit to gain more knowledge of the object. From observations from the visit and available statistics on fi

Gång på gång: En analys av rekvisitet “upprepad kränkning” vid grov kvinnofridskränkning

Grov kvinnofridskränkning infördes i svensk rätt 1998 för att möta ett rättsskyddsbehov som tidigare straffbestämmelser inte förmådde tillgodose. Syftet var att straffrättsligt synliggöra den systematiska karaktären av våld och kränkningar som många kvinnor utsätts för i nära relationer. Genom att kriminalisera ett mönster av gärningar, snarare än enstaka händelser, har lagstiftaren försökt fånga Gross violation of a woman’s integrity was introduced into Swedish law in 1998 to address a legal protection gap that previous criminal provisions failed to cover. The aim was to legally acknowledge the systematic nature of abuse and repeated violations that many women are subjected to in close relationships. By criminalising a pattern of acts rather than isolated events, the legislator intended t

Fult spel eller misshandel? - Social adekvans och ansvarsfrihet i samband med idrott

I svensk rätt finns skrivna undantagsregler som utesluter ansvar för en gärning. Det kan vara gärningar som uppfyller rekvisiten för misshandel men ändå undgår ansvar när det finns ett intresse som väger tyngre. Detta är dock inte tillräckligt för att förhindra alla former av ”oskyldiga” gärningar från att straffas när de formellt faller in under ett straffbud. Socialadekvata gärningar är sådana

Skyldighet att höra, men ingen plikt att lyssna? Om barns rätt till delaktighet

Barnets bästa ska vara avgörande för alla frågor om vårdnad, boende och umgänge. Barnets åsikter är en viktig del i bedömningen och som regel får barn, om det inte bedöms som olämpligt, komma till tals. Det är dock långt ifrån självklart att deras åsikter faktiskt påverkar utgången. Ett barn som motsätter sig att träffa en förälder kan ändå få umgänge beslutat av domstol trots att umgänge enligt lThe best interests of the child should be decisive in all matters concerning custody, residence and visitation. The child’s views are an important part of this assessment, and children are generally given the opportunity to express their opinions, unless it is deemed inappropriate. However, it is far from certain that these opinions actually influence the outcome. Even if a child opposes visiting

Algorithms for the multimodal acoustophoresis control of particle trajectories

Styrning av partiklar med ljud och intelligenta algoritmer Det här examensarbetet handlar om att styra små partiklar i vätska utan att röra vid dem, med hjälp av ljud. Genom en teknik som kallas multimodal akustofores kombineras flera olika ljudvågor för att noggrant kunna påverka partiklarnas rörelser. Metoden är särskilt intressant inom biomedicin, till exempel vid analys av enskilda celler ellThis thesis explores a range of control algorithms for multimodal acoustophoresis, the process of manipulating particles in a fluid by simultaneously using several acoustic modes. The aim of the algorithms is to precisely guide particle trajectories in acoustofluidic systems, motivated by the demand for non-invasive, scalable manipulation techniques in biomedical applications such as single-cell a

Vad kommuniceras med biblioteksplanen? En dokumentstudie kring biblioteksplanens utformning i relation till det kommunala självstyret

This master’s thesis is a qualitative content analysis of nine municipal library plans (and two county library plans) with a basis in new institutionalism, specifically in regards to legitimacy, homogeneity as well as themes and patterns in the sourcematerial. With a basis in the history of the library plan and the municipal gouvernance, debate in regards to cultural policy, the downsizing of libr

Functional Characterization of an Oat Lipase Candidate

Oats (Avena sativa) are a valued food product due to their nutritional profile and proven health benefits. However, prior to consumption, they require heat processing to prevent off-flavors and undesirable mouthfeel caused by lipase-catalyzed hydrolysis of lipids. While the heat treatment inactivates lipases, it raises concerns regarding sustainability and oat quality. The discovery of novel funct

Design and Analysis of Antenna Selection in Massive MIMO

Mobile communications have evolved with the commercial deployment of 5G and initial studies of 6G. New solutions and innovative technologies are being incorporated to reach the target requirements. One of the key technologies in mobile networks is massive multiple-input-multiple-output (MIMO). Increasing the number of antennas offers significant benefits in coverage, reliability, and spectral effi

Performance Evaluation of 802.15.4 UWB PHY for High Speed Data Rate under IEEE Channel Mode

In modern day society the increase of data generation and transfer has been an issue that researchers are working on. This generated and shared data might have a different purpose but one thing is certain, the reception. This communication can cover continents, countries, cities or even just a few meters. For the purpose of the later, personal area networks (PAN) have been created with a main focu

Secure Domain Transition of Calvin Actors

Calvin, an Ericsson application framework for Internet of Things (IoT), simplifies the development and deployment of applications for IoT systems where many heterogeneous devices are deployed and connected through the Internet. The application engineer just needs to design and codify the application applying Calvin syntax. The Calvin environment is formed by runtimes and applications. The runtime

I skuggan av våldet - Om barns straffrättsliga skydd vid bevittnande av våld mellan närstående

Våld i nära relationer är ett allvarligt och alarmerande samhällsproblem. I skuggan av våldet lever hundratusentals barn som tvingas bevittna våldet på nära håll. Uppsatsen syftar till att redogöra för samt analysera det straffrättsliga skydd för barn som bevittnar våld genom användning av en rättsanalytisk metod. Materialet som använts för uppsatsens framställning grundas på de allmänna rättskällDomestic violence is a serious and alarming social problem. Hundreds of thousands of children live in the shadow of domestic violence, forced to witness the brutality up close. The aim of this thesis is to describe and analyze the criminal justice protection available to these children by using a forensic method. The material used for this essay is based on the general sources of law together with