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Glucose-dependent insulinotropic polypeptide (GIP) receptor knockout (KO) mice are tools for studying GIP physiology. Previous results have demonstrated that these mice have impaired insulin response to oral glucose. In this study, we examined the insulin response to intravenous glucose by measuring glucose, insulin and C-peptide after intravenous glucose (0.35 g/kg) in 5-h fasted female GIP recep
In this paper, we address surgical aspects on bariatric surgery in adolescents from a nationwide Swedish study. Laparoscopic gastric bypass surgery was performed for 81 adolescents with morbid obesity (13-18 years), while 81 adolescents with obesity-matched by age, sex, and BMI received conventional care. Another comparison group was adults undergoing gastric bypass at the same institution during
Objectives To investigate, using a Dutch model, whether and under what variables framed for other European countries screening for human papillomavirus (HPV) is preferred over cytology screening for cervical cancer, and to calculate the preferred number of examinations over a woman's lifetime. Design Cost effectiveness analysis based on a Dutch simulation model. Base case analyses investigated the
BACKGROUND: /st>The relative respiratory effects of fentanyl and remifentanil, administered as i.v. bolus, have not previously been studied. We determined what remifentanil bolus dose gave the same maximum depression of ventilation as 1 µg kg(-1) of fentanyl. METHODS: /st>Twelve healthy volunteers rebreathed in a system designed to dampen variations in end-tidal carbon dioxide tension so that me
INTRODUCTION: This investigation aimed to evaluate thrombotic risk factors in children, with special reference to autoantibodies against prothrombin and protein S. MATERIALS AND METHODS: We studied 57 consecutive Swedish children and adolescents referred with a radiologically confirmed acute thrombotic event. Clinical data were collected and a thrombophilia investigation was performed, including a
PURPOSE: The study aimed to (1) optimize the radiation doses of computed tomography (CT) of paranasal sinuses, (2) compare the radiation doses of different CT protocols with that of plain radiography, and (3) evaluate the reliability of low-dose CT in the detection of pathology and characterization of the detected pathology. MATERIALS AND METHODS: A head phantom was examined with different scan pa
Abstract BACKGROUND: Most individuals with Helicobacter pylori infection in Western countries have no evidence of peptic ulcer disease (PUD). We therefore assessed the PiZ deficiency variant of the major plasma protease inhibitor alpha1-antitrypsin (alpha1AT) as a risk factor for PUD in H. pylori-infected individuals. METHODS: The cohort comprised 100 patients with endoscopically or surgically pr
Introduction: Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) is a technique combining vaginal entrance to the abdomen with endoscopic overview. Previous studies have shown that vNOTES decreases operating time, hospitalization, postoperative complications, and pain. We aimed to present patient demographics, costs, and surgical outcomes following the implementation of vNOTES for be
In this study, different membranes were tested for their use in a vanadium redox flow battery (VRB). The membranes were first tested under charge-discharge operation of the VRB over four charge-discharge cycles at different current densities (20 mAcm-2, 40 mA cm-2 and 60 mAcm-2) and the corresponding cell performance was evaluated in terms of total energy efficiency (EE), coulombic efficiency (CE)
We have calculated redox potentials of 12 blue copper protein sites comparing 64 computational methods, systematically varying the quantum mechanics (QM) system size, dielectric constants, density functional, and basis sets. All methods were based on structures optimized with combined QM and molecular mechanics (QM/MM) approaches. The redox potentials were evaluated using 10 quality metrics. The b
Purpose: In a multicenter prospective cohort study, we assessed the diagnostic yield of the Nordic guidelines for germline investigation in myeloid neoplasms and mapped the spectrum of inherited and somatic variants. Experimental Design: Eighty-five patients (acute myeloid leukemia, n = 38; myelodysplastic syndromes, n = 26; thrombocytopenia, n = 14; and other, n = 7) fulfilling the Nordic criteri
Baobab (Adansonia digitata) seeds are a source of valuable lipids with notable nutritional and functional attributes. In response to the rising demand for sustainable, high-quality oils in the cosmetic and nutraceutical sectors, there is an increasing interest in environmentally friendly extraction techniques that maintain lipid bioactivity while reducing the use of toxic solvents. This study repr
Aims: To examine the separate associations of glycemic control and chronic kidney disease with hospitalization days over one year in patients with type 2 diabetes (T2D). Materials and methods: A cross-sectional study using retrospective data on T2D patients in Region Halland, Sweden, during 2020. Data from the Region Halland database included hospitalizations, emergency visits, primary care encoun
Godstransporter är en grundläggande förutsättning för samhällsekonomisk utveckling, näringslivets konkurrenskraft och tillgången till varor, men står samtidigt för en betydande andel av Sveriges växthusgasutsläpp. Att minska transporternas klimatpåverkan utan att hämma ekonomisk utveckling är därför en central utmaning. Ökad transporteffektivitet lyfts ofta fram som en nyckelstrategi, men dess potFreight transport is a fundamental prerequisite for socio-economic development, business competitiveness, and the availability of goods, while at the same time accounting for a substantial share of Sweden’s greenhouse gas emissions. Reducing the climate impact of transport without constraining economic development therefore constitutes a central challenge. Improved transport efficiency is often hi
BACKGROUND: Multiple medicine use among elderly persons is likely to be the result of treatment regimens developed over a long period of time. By learning more about how multiple medication use develops, the quality of prescribing may be improved across the adult lifespan. OBJECTIVE: To describe patterns of multiple medicine use in the general Swedish population and its association with sociodemog
Introduction: The aim of this study was to investigate the 1986-1994 trend in obesity, overweight and sedentary leisure-time physical activity status, and the educational gradient in overweight and obesity in the city of Malmö, Sweden. Material/Methods: The public health surveys in Malmö 1986 and 1994 are cross-sectional studies. A total of 4,800 and 5,600 individuals aged 20–80 years were randoml
Popular Abstract in Swedish Att reducera energianvändningen för belysning i byggnader är viktigt för att uppnå målet att minska koldioxidutsläppen. Ett sätt att nå målet är om vi kan förändra människors beteende vilket kan ge en stor energibesparing. Feedback rörande energianvändning har ofta använts för att förändra beteende, men effektiviteten hos detta tillvägagångssätt är mer ifrågasatt för apThe lowering of energy use from artificial lighting in buildings is vital to reaching the goal of reducing CO2 emissions. Hence, changes in individuals’ behaviours regarding lighting use have received increased attention. Feedback on energy use has often been used to change individuals’ behaviour. However, it is not clear to what extent this approach can be applied for non-residential buildings, w
In bottom-up mass spectrometry (MS)-based proteomics, peptide isotopic and chromatographic traces (features) are frequently used for label-free quantification in data-dependent acquisition MS but can also be used for the improved identification of chimeric spectra or sample complexity characterization. Feature detection is difficult because of the high complexity of MS proteomics data from biologi
Popular science summary To Migrate or Not to Migrate! An interesting experiment to test how gender, personality traits, size, and condition affect migration in Roach (Rutilus rutilus). Partial migration is a phenomena in which migration does not take place in every individual’s lifecycle. The reason for this type of migration has not yet been totally understood. However, there has been studies
Familjeåterförening är en viktig princip inom både svensk och internationell rätt. I svensk rätt regleras denna princip i utlänningslagen där en möjlighet till uppehållstillstånd på grund av anknytning ges. Vissa bevisrättsliga frågor måste dock uppfyllas för att uppehållstillstånd ska kunna ges. I denna framställning behandlas bevisning angående ställföreträdarskap för barn som söker uppehållstilFamily reunification is an important principle in both Swedish and international law. In Swedish law this principle is coded into the Aliens Act making it possible to get residence permit on the grounds of ties to Sweden. In order to get a residency permit there are a couple of things you have to prove, for example your identity and the existence of a relation to a person in Sweden. If you are und
