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Introduction: After extensive pelvic surgery for cancer two flap types are used at Skåne University Hospital (SUS), Sweden for perineal reconstruction: vertical rectus abdominis myocutaneous flap and gluteal flap with or without vaginal reconstruction. The objective was to study the long-term outcomes in patients treated for advanced pelvic cancer receiving a flap. Method: Patients with pelvic can
Climate change affects organisms worldwide with profound ecological and evolutionary consequences, often increasing population extinction risk. Climatic factors can increase the strength, variability, or direction of natural selection on phenotypic traits, potentially driving adaptive evolution. Phenotypic plasticity in relation to temperature can allow organisms to maintain fitness in response to
Data on the impact of long term treatment with immunomodulatory drugs (IMiD) on health-related quality of life (HRQoL) is limited. The HOVON-87/NMSG18 study was a randomized, phase 3 study in newly diagnosed transplant ineligible patients with multiple myeloma, comparing melphalan-prednisolone in combination with thalidomide or lenalidomide, followed by maintenance therapy until progression (MPT-T
Aerosol emissions from anthropogenic activities cause detrimental health effects and affect the climate system. Combustion is a large source of airborne fine particulate matter (PM2.5) and the uncertainties of the climate role of these emissions are still large. A good understanding of the microphysical properties of aerosols from various sources and their atmospheric aging is essential for accura
The market of connected devices, IoT devices in particular, is hotter than ever. Today, lightweight IoT devices are used in several sectors, such as smart cities, smart homes, healthcare, and the manufacturing industry.IoT solutions help increase productivity by predictive maintenance and resource management in the industry. Devices with voice interfaces are spreading rapidly in the home automatio
Businesses today need to recognize that they have to be fast at realizing and exploiting new competitive advantages before the opportunity is lost. Instead of the traditional focus on price and quality, there is a shift towards the delivery of value to customers. This is strongly connected to the reduction of downtime of production and high reliability. Here the spare parts supply chain plays an i
Increasing tree species diversity is known to enhance soil organic carbon (SOC) stocks, but its effect on SOC stability remains a critical uncertainty for climate mitigation. Through examination of a subtropical karst forest diversity gradient in southwest China, we reveal a fundamental shift in SOC stabilization mechanisms using physical fractionation, 13C nuclear magnetic resonance spectroscopy
Mycelial residues, also known as fungal necromass, represent a substantial fraction of soil organic matter (SOM) pools in terrestrial ecosystems worldwide. Although microbial decomposers are increasingly recognised as key drivers of fungal necromass carbon stock formation, the diversity and composition of their microbial predators—and the roles these predators play in mediating fungal necromass de
Pollination by bees is important for food production. Recent concerns about the declines of both domestic and wild bees, calls for measures to promote wild pollinator populations in farmland. However, to be able to efficiently promote and prioritize between measures that benefit pollinators, such as modified land use, agri-environment schemes, or specific conservation measures, it is important to
Synnerligen grov misshandel är en brottstyp som introducerades i svensk straffrätt år 2010, detta efter att regeringen uttryckt att straffskärpningar behövdes då man inte ansåg att de utdömda straffen var proportionerliga i förhållande till brottets allvar. Flertalet fall har sedermera hamnat i HD och hovrätterna och en praxis har skapats kring vad brottet innebär. Stort fokus läggs på hänsynslöshExceptional aggravated assault is a crime which was introduced to Swedish criminal law in 2010. The reason behind this was the fact that the Swedish government believed that harsher punishments were needed due to the fact that they were not proportional in comparison to the seriousness of the crime. Regarding what is to be considered as exceptional aggravated assault, the courts tend to focus on t
Europe has experienced several climate extremes during the past decades. These extreme events have increased in number and intensity and are projected to further intensify. Previous studies show that heatwaves, drought, and flood can have an impact on water quality in several ways. Drought can cause reduced dilution of nutrients, limiting oxygen availability as a result of increased water temperat
The effectiveness of psychosocial interventions in community mental healthcare has been shown to depend on the setting in which they are implemented. Recently structured patient-clinician communication was found to be effective in a multi-centre trial in six European countries, the DIALOG trial. In the overall study, differences between centres were controlled for, not studied. Here, we test wheth
Background: Alcohol use disorders (AUD) involving hazardous, harmful, and addictive misuse of alcohol are widespread in most parts of the world. The aim of this study was to review the effect of disulfiram in the treatment of patients with AUD. The effect of disulfiram was evaluated according to the primary outcome of an intake of alcohol below 30 and 20 g/d for men and women, respectively, as we
Pollution-induced community tolerance (PICT) was used to study effects of phenol on soil bacteria. Phenol was added to an agricultural soil in a microcosm experiment. The effects were studied for up to four months. Bacterial growth rates were estimated with the leucine incorporation technique. This technique was also used as detection method for PICT. Changes in community structure were studied us
We have previously described the efficient guidance and unidirectional sliding of actin filaments along nanosized tracks with adsorbed heavy meromyosin (HMM; myosin II motor fragment). In those experiments, the tracks were functionalized with trimethylchlorosilane (TMCS) by chemical vapor deposition (CVD) and surrounded by hydrophilic areas. Here we first show, using in vitro motility assays on no
Popular Abstract in Swedish ”Luffarturismen” har blivit en populär form av resande. Många svenskar för under en tid - ibland flera månader eller år - en vagabonderande tillvaro på platser långt hemifrån. Resan blir en parentes i vardagen - en extraordinär sfär fylld av förväntningar på äventyret och den äkta upplevelsen. Vad har resenären för bild av det ”Långtbortistan” hon lockas av, och hur skThis dissertation, The Attraction of the Extraordinary - Images and Experiences Among Backpacker Tourists, is a study based on informal interviews with predominantly Swedish independent travellers, as well as observations and documentary analysis of the backpacker subculture. Backpacking is a type of tourism which has been gradually institutionalized. Through the institutionalization of the backpa
Lung scintigraphy is the primary tool for diagnostics of pulmonary embolism. A perfusion study is often complemented by a ventilation study. Intermediate probability scans are frequent. Our goal was to develop a fast method for tomographic ventilation and perfusion scintigraphy to improve the diagnostic value of lung scintigraphy. METHODS: SPECT was performed with a dual-head gamma camera. Acquisi
During the 1990s public services have to a great extent reorganised according to the idea of market economy and new management ideas. An example that illustrates these processes is the home care organisations. Private companies, new management strategies and special need assessment officials have been introduced. In a longitudinal study we have focused on the fate of the working teams as it is sho
