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The number of people suffering from the unpleasant symptoms of allergic rhinitis is increasing due to environmental and other factors. This not only makes life difficult for the individual but also places a heavy burden on society, which is why treatment is needed. Rhinocort® is a nasal spray suspension manufactured by McNeil AB to reduce the severity of symptoms, and like all medicines, must und

Scientific studies indicate that the effects of the ongoing climate crisis negatively affect and sometimes also threaten the built environment, humanity and nature in many ways. Cloudbursts and rising sea levels are two examples of such effects, which result in complex dilemmas and interesting challenges that planners and urban designers face within their field of work. These two effects are notic

Background: Accumulation of saturated fatty acids (SFAs) in the liver is known to induce hepatic steatosis and inflammation causing non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). Although SFAs have been shown to affect the epigenome in whole blood, pancreatic islets, and adipose tissue in humans, and genome-wide DNA methylation studies have linked epigenetic ch

Prostate cancer bone metastasis is still not fully understood, and increased knowledge could aid in the development of better treatment options for patients in the future. This thesis focuses on microRNAs (miRNAs), which modulate gene expression in healthy and tumour cells. Using cell culture, animal and patient studies, we investigated the biological role of microRNA-96 (miR-96) and microRNA-379

Background: Sedation is often provided to resuscitated out-of-hospital cardiac arrest (OHCA) patients to tolerate post-cardiac arrest care, including temperature management. However, the evidence of benefit or harm from routinely administered deep sedation after cardiac arrest is limited. The aim of this trial is to investigate the effects of continuous deep sedation compared to minimal sedation o

Aim: Allometric relationships, which describe plant growth patterns shaped by environmental conditions, reflect functional trade-offs and represent key functional traits that optimise adaptation, resource acquisition, stress tolerance and competition. Here, we assess how these allometric relationships and associated functional trade-offs drive ecosystem structure, functioning and competitive inter

INTRODUCTION: Total alloplastic replacement of the temporomandibular joint (TMJ) is a viable treatment option for severe TMJ disorders (TMDs) unresponsive to conservative approaches, as well as for reconstruction of congenital or acquired TMJ defects. However, clinical data on indications, outcomes, complications and long-term effects remain limited, and no global registry currently exists. This s

Precise synchronization of paleoclimate records is essential for inferring the dynamics and past evolution of the climate system. For the last glacial period, the time scales of ice cores from the Greenland and Antarctic ice sheets have been synchronized by the use of cosmogenic radionuclides, atmospheric gas concentrations, and traces of large volcanic eruptions. Here we identify the sulfate depo

INTRODUCTIONBoreal forests are crucial for mitigating global climate change by capturing and storing large amounts of atmospheric carbon dioxide. However, previously unmanaged primary boreal forests are being rapidly transformed to managed secondary forests to meet the rising global demand for materials and energy. Understanding the effects of boreal primary to managed secondary forest transformat

Kan flexibilitet i hushålls energisystem underlätta energiomställningen genom att dra nytta av volatila elpriser? Analysen av vår fallstudie visar att flexibla teknologier och framför allt värmeproduktion från el kan minska fossila utsläpp och driftkostnader, men ökar elanvändningen från nätet. Priserna på el har diskuterats frekvent de senaste åren och kraftiga prissvängningar har negativt påveThe increasing share of weather-dependent renewable energy in the European electricity system, as a consequence of the European Union’s climate ambitions, has led to increased spot price volatility, negatively affecting consumers due to unpredictability. This case study assesses how flexibility (including power-heat cross vector flexibility) in residential buildings can affect annual costs, emissi

Background: Ambulatory oxygen therapy can be used to treat exertional hypoxaemia during daily life activities in people with fibrotic interstitial lung disease (ILD). However, evidence for its efficacy is scarce. This trial aimed to compare the effects of ambulatory oxygen with ambulatory air on physical activity in daily life over 6 months in people with fibrotic ILD and isolated exertional hypox

För att beviljas asyl måste queera asylsökande inför myndigheterna bevisa att de verkligen är queera. Om de inte gör det avslås deras ansökan som icke trovärdig och de riskerar att utvisas till sina ursprungsländer. I denna avhandling utforskar jag, genom möten med beslutsfattare, jurister, asylsökande och flyktingar, den affektiva produktionen av (o)trovärdig queerness inom det grekiska asylsysteTo be granted asylum, queer applicants must prove to the examining authorities that they are genuinely queer. Otherwise, their claims are rejected as non-credible, placing them at risk of deportation. In this thesis, I explore the affective production of (in)credible queerness in the Greek asylum apparatus. Through encounters with decision-makers, lawyers, asylum seekers, and refugees, I discuss t

Parasites play a fundamental role in explaining variation in population dynamics in wild ecosystems while also acting as a better model-system to study similar or related human infections. Since the late 1800s, malaria parasites have played a crucial role in vector-borne disease research. Many intrinsic and environmental factors can affect the level of infection transmission and prevalence among a

Innovation literature shows that the characteristics of a company's innovation processes determine their performance in different areas. In this study, we adopt a general conceptual model from innovation theory and apply it to packaging innovation. This helps identify and describe subprocesses in packaging innovation and how to measure their performance. It also links the packaging innovation proc