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cGMP interactors play a role in several pathologies and may be targets for cGMP analog-based drugs, but the success of targeting depends on the biochemical stereospecificity between the cGMP-analog and the interactor. The stereospecificity between general cGMP analogs—or such that are selectivity-modified to obtain, for example, inhibitory actions on a specific target, like the cGMP-dependent prot

Popular Abstract in Swedish Denna avhandling bygger på ett studium av romerska glaskärl funna på icke-romerska/inhemska fyndorter — huvudsakligen tillhörande den romerska järnåldern (0–400 e.Kr.) — bortom Hadrianus mur i norra Britannien. Romerska glaskärl har påträffats på inalles 60 fyndorter, varav en stor del utgörs av bosättningar av skilda slag, och endast en liten del härrör från gravar. So

The Arabidopsis MAP kinase 4 (MPK4) substrate MKS1 was expressed in Escherichia coli and purified, full-length, 6x histidine (His)-tagged MKS1 was phosphorylated in vitro by hemagglutinin (HA)-tagged MPK4 immuno-precipitated from plants. MKS1 phosphorylation was initially verified by electrophoresis and gel-staining with ProQ Diamond and the protein was digested by either trypsin or chymotrypsin f

In this thesis the notion of place is studied by way of investigating the “non-place” which is excluded or opposed, whenever a place is defined. “Non-place” is used here as a meta-concept, covering various recurring types of opposition to “place,” and it therefore represents a profoundly incoherent spect-rum of realities and concepts. Hence, a “non-place” may in this investigation appear as “lefto

My written contribution responds to the questions: How des your practice relate to placemaking? How is it possible to use sense of place as material and starting point for research or artistic work? What methods do you use for co-creation and relationship building in relation to place?

Popular Abstract in English As far as we know the Northern Fulmar (just referred to as Fulmar from her on), did not start breeding on the Faroe Islands before about 150 years ago. But it has been known by the Faroese for a long time. Mainly as a bad omen and according to folklore fishermen would return home if they encountered Fulmars when out at sea, since they believed it was the bringer of storThe Northern Fulmar (Fulmarus glacialis) is one of the most abundant seabirds in the Northern Hemisphere and the most abundant seabird on the Faroe Islands. Except from a few sporadic observations up until the 1950´s no study has focused on this species on the Faroe Islands. Being considered a significant consumer of marine resources in the Faroese marine ecosystem a closer study of this species´

Investigations over two major tectonic zones in the Hallandsås Horst, Southern Sweden were carried out in connection with a railway tunnelling project. A combination of resistivity imaging, core drilling and geophysical logging was found to provide a good overview of the variation in rock quality and detailed information on the engineering geological characteristics and genesis of the strata. Resi

Eutrophication is one of the most serious global threats to coastal areas. One effect of eutrophication is seasonal macroalgal blooms. As a consequence, large amounts of beach-cast algae are today reported from coastal areas worldwide. In this study, we analyze nonmarket benefits by capturing local residents' Willingness To Pay (WTP) for an environmental program to regularly remove and utilize beaEutrophication is one of the most serious global threats to coastal areas. One effect of eutrophication is seasonal macroalgal blooms. As a consequence, large amounts of beach-cast algae are today reported from coastal areas worldwide. In this study, we analyze nonmarket benefits by capturing local residents' Willingness To Pay (WTP) for an environmental program to regularly remove and utilize bea

Drought is projected to increase in frequency and intensity and impacts trees with increased water stress and increased mortality rate. Water stresses can cause hydraulic failure-related mortality or carbon starvation due to tree species having different strategies to deal with water stresses. LPJ-GUESS-HYD (Hydraulic implementation of a new plant hydraulics scheme in LPJ-GUESS) was developed to i

Kv. Renen 13 i centrala Varberg är sedan tidigare känt som kraftigt förorenat. På fastigheten har det från slutet av 1800-talet fram till 2003 funnits verksamheter i form av textilindustri som avlösts av finmekanisk verkstadsindustri. Det är framförallt den sistnämnda verksamheten som har orsakat rådande situation med höga halter klorerade lösningsmedel, trikloreten (TCE) och 1,1,1-trikoletan (TCAAn old industry estate, Kv. Renen 13, is located in central Varberg, southwest Sweden, and is known from previous investigations as highly polluted. Pollution started in the late 19th century with textile manufacturing, and in the 1960´s changed into a precision mechanics industry using chlorinated solvents, primary trichloroethene (TCE) and 1,1,1-trichloroethane (TCA), as well as cyanide and meta