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Electron paramagnetic resonance spectroscopy of site-directed spin labels reveals the structural heterogeneity in the N-terminal domain of apoA-I in solution
Apolipoprotein A-I (apoA-I) is the major protein constituent of high density lipoprotein (HDL) and plays a central role in phospholipid and cholesterol metabolism. This 243-residue long protein is remarkably flexible and assumes numerous lipid-dependent conformations. Consequently, definitive structural determination of lipid-free apoA-I in solution has been difficult. Using electron paramagnetic
Synthesis, Structures and Oxo Transfer Reactivity of bis(Dithiolene) Tungsten(IV,VI) Complexes Related to the Active Sites of Tungstoenzymes
Effects of baseline P-wave duration and choice of atrial septal pacing site on shortening atrial activation time during pacing.
Structural and Functional Models of the Active Site of Zinc Phosphotriesterase
Pharmacophore Refinement and Lead Optimization - A study of the benzodiazepine site of the GABAA receptors
Popular Abstract in Swedish Kemi förknippas ofta med miljöförstöring och gifter och det kan vara lätt att bortse från att dagens samhälle genomsyras och är beroende av produkter tillverkade med kemins hjälp. Läkemedel är exempel på kemiska produkter som alla kommer i kontakt med och i vissa fall inte kan leva utan. Organisk kemi, en viktig undergrupp i det vida begreppet kemi, är en vetenskap som
Scavenging of ultrafine particles by rainfall at a boreal site: observations and model estimations
On exposure to anorexia nervosa, the temporal variation in axial and appendicular skeletal development predisposes to site-specific deficits in bone size and density : A cross-sectional study
Skeletal development is heterogeneous. Throughout growth, bone size is more maturationally advanced than the mineral being accrued within its periosteal envelope; before puberty, appendicular growth is more rapid than axial growth; during puberty, appendicular growth slows and axial growth accelerates. We studied women with differing age of onset of anorexia nervosa to determine whether this tempo
Comparison of soldier fly (Diptera: Stratiomyidae) and thick-headed fly (Diptera: Conopidae) diversity at two trapping sites
Jämförelse av två flugfamiljers mångfald i två olika naturtyper Djurs mångfald är inte bara intressant utan även viktigt för att vår värld ska fungera i harmoni och kretsloppen ska slutas och gå runt. Vissa djur behövs för att bryta ned vissna växter och andra för att hålla insekters antal i schack. Några djur kan även vara tecken på om naturen mår bra eller dåligt. Olika naturtyper är hem för olBiodiversity is a big part of the understanding of our life and its surroundings. Only a fraction of the earth’s species are known and many are yet to be found. When describing new species often both molecular and morphological data is needed to fully resolve cryptic taxa. In this study, the diversity of two Diptera families, soldier flies (Stratiomyidae) and thick-headed flies (Conopidae), have b
Azaflavones compared to flavones as ligands to the benzodiazepine binding site of brain GABA(A) receptors.
Detection by near-infrared spectroscopy of large lipid cores at culprit sites in patients with non-st-segment elevation myocardial infarction and unstable angina
ObjectiveThis study was performed to assess the lipid burden of culprit lesions in non-ST-segment elevation myocardial infarction (non-STEMI) and unstable angina (UA). BackgroundA recent intracoronary near-infrared spectroscopy (NIRS) study showed 85% of STEMI culprit lesions have a maximum lipid core burden index in 4-mm (maxLCBI(4mm))400. Whether culprit lesions in non-STEMI and UA are character
Management of saltpans as potential foraging sites for shorebirds
Abstract Estuaries and salt marshes are important wetlands used by waterbirds during winter and migration. However, many salt-marshes have been transformed into salinas, which currently function as high-tide roosts. Since traditional salt production is no longer profitable, many salinas have been abandoned or converted into aquaculture potentially becoming less attractive to waders. In this study
Simple and farmer-friendly bumblebee conservation : Straw bales as nest sites in agricultural landscapes
Immunohistochemical localization of the calcitonin gene-related peptide binding site in the primate trigeminovascular system using functional antagonist antibodies
Sustainable drainage system site assessment method using urban ecosystem services
Crystal structure of β-glucosidase 1A from Thermotoga neapolitana and comparison of active site mutants for hydrolysis of flavonoid glucosides
The β-glucosidase TnBgl1A catalyses hydrolysis of O-linked terminal β-glycosidic bonds at the nonreducing end of glycosides/oligosaccharides. Enzymes with this specificity have potential in lignocellulose conversion (degrading cellobiose to glucose) and conversion of bioactive flavonoids (modification of glycosylation results in modulation of bioavailability). Previous work has shown TnBgl1A to hy
Site-selective 13C labeling of proteins using erythrose
Siliceous Raw Material Exploitation at Hort de la Boquera Site (Margalef de Monsant, Tarragona, España) : First Results from La-Icp-Ms Analysis
Research on the sourcing of siliceous raw materials in Prehistory has taken a step forward with the addition of geochemical techniques and elemental analysis to the archaeopetrological method. Counter to the macroscopic techniques, which retain an elevated subjective percentage in their results, geochemical techniques and especially LA-ICP-MS analysis generate objective, quantifiable and usable da
