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Ribonucleotide reductase (RNR) is the only source for de novo production of the four deoxyribonucleoside triphosphate (dNTP) building blocks needed for DNA synthesis and repair. It is crucial that these dNTP pools are carefully balanced, since mutation rates increase when dNTP levels are either unbalanced or elevated. RNR is the major player in this homeostasis, and with its four different substra
Efficient and clean production of electrical energy and mechanical (shaft) energy for use in industrial and domestic applications, surface- and ground transportation and aero-propulsion is currently of significant general concern. Fossil fuels are mainly used for transportation and aero-propulsion, but also for power generation. Combustion of fossil fuels typically give rise to undesired emissions
This paper aims to discuss street art as new form of art and activism of uncomissioned and unsanctioned artifacts including paintings, murals and various kinds of stencils, posters, and stickers applied in any public surface. As Bengtsen (2014) has argued street art is a sociocultural practice, which is performative, ephemeral, and site specific. Street art has much to tell us about the dialectics
In the vehicular communication channels, the mobility of the receiver (RX) and the transmitter (TX) along with the movements of interacting objects in the propagation environment result in significant non-stationary channel fading. The channel impulse response exhibits not just significant delay- and Doppler spreads, but also the delay- and Doppler spreads themselves are changing over the time- an
The aim was to investigate clinical predictors of adherence to antipsychotics. Medication use was electronically monitored with a Medication Event Monitoring System (MEMS(®)) for 12 months in 112 outpatients with schizophrenia and schizophrenia-like psychosis according to DSM-IV. Symptom burden, insight, psychosocial function (PSP) and side effects were rated at baseline. A comprehensive neuropsyc
The aim of this study is to understand the mechanisms behind the diffusion of fired bricks in Hellenistic Europe, initiated in the north Aegean in the 4th century BC. To this end, a social diffusion model is used to simulate the available archaeological data pertaining to this process. The starting point in the construction of the model is the assumption that different categories of people contrib
Purpose:To find out differences in cerebral blood volume (CBV) maps derived from dynamic susceptibility contrast-enhanced magnetic resonance imaging (DSCE-MRI) in glioblastomas and cerebral metastases. The main purpose was to compare CBV maps between metastases with different primary malignancies. Furthermore the metastasis group was compared with the glioblastoma group.Method:Conventional imagi
The increased demand for high purity nanoparticles (NPs) of defined geometry necessitates the continuous development of generation routes. One of the most promising physical techniques for producing metal, semiconductor or alloy NPs in the gas phase is spark discharge NP generation. The technique has a great potential for up-scaling without altering the particles. Despite the simplicity of the set
Uppsatsen syftar till att undersöka hur diskrimineringslagen (2008:567) och föräldraledighetslagen (1995:584) skyddar föräldralediga och gravida mot diskriminering och missgynnade samt hur dessa regelverk samverkar. Vidare utreds också Arbetsdomstolens tillämpning av jämförelse i föräldraledighetslagen och rekvisitet jämförbar situation i diskrimineringslagen. En analys av eventuella skillnader i The purpose of this thesis is to examine how the Discrimination Act and the Parental Leave Act protect individuals on parental leave and pregnant women from discrimination and disadvantageous treatment, as well as how these laws interact. It also aims to analyze the Swedish Labour Court's application of the concept of comparison in the Parental Leave Act and the requirement of a comparable sit
Syftet med artikel 102 FEUF är att förbjuda vissa konkurrensmetoder från att användas, av företag med en dominant ställning på sin relevanta marknad. Anledningen är att konkurrensen ensam inte alltid kan begränsa dominanta företags handlingsfrihet, vilket skapar utrymme för missbruk, till skada för både konkurrenter och konsumenter. Ett exempel på missbruk är rovprissättning, där ett företag
Denna kvalitativa studie syftar till att undersöka psykoterapeuters erfarenhet av existentiella frågor i behandling. Studien utforskar med hjälp av semistrukturerade intervjuer och tematisk analys hur deltagarna upplever att de existentiella villkoren döden, meningslöshet, ensamhet och frihet påverka patienterna Den undersöker även hur psykologer arbetar med dessa frågor i terapi samt vilken effekThis qualitative study aims to explore psychotherapists' experiences of existential concerns in treatment. Using semi-structured interviews and thematic analysis, the study examines how participants perceive the existential givens death, meaninglessness, isolation, and freedom to have influenced their clients. The study also investigates how psychologists address these themes in therapy and th
In 2022, approximately 32 million patients worldwide suffered from Alzheimer’s disease dementia. In addition to this, about 380 million people carried the biomarkers indicating Alzheimer’s, while displaying little to no symptoms. These people, however, always live with the risk of the disease progressing - making the development of a drug that can slow down or stop progression an endeavour of glob
Syftet med arbetet har varit att, med hjälp av bayesiansk sannolikhetsteori som bevisvärderingsmetod, kritiskt analysera svenska människohandelsmål. Detta har gjorts för att utröna om det förekommer tecken på bristande bevisvärdering från domstolarna som bidrar till att rekvisit ej anses styrkta i dessa mål där någon blir friad, och i utsträckning bidragit till bevisproblematik kring brottet. SyftThe purpose of this paper has been to critically analyze Swedish court cases of human trafficking where the accused has been acquitted of such a criminal act. The critical analysis has been executed with the aid of Bayesian probability theory as an evidence evaluation method. This has been done to determine whether there are signs of flawed evidence evaluation from the court itself which has contr
In the realm of urban planning, urban greening – the creation or restoration of green spaces in cities – has risen as an attractive approach for policy-makers and planners engaged in sustainability. As the benefits of urban greening are many, from social and cultural to environmental and economic, it has become positioned as a win-win solution to several urban challenges related to sustainable dev
To meet the growing demand of meat alternatives, this project was dedicated to creating a chicken analogue prototype with mycoprotein. Within the project, two approaches of alginate gelation, external (diffusion) crosslinking and internal crosslinking, were studied in this particular food matrix. Using the external crosslinking method, the effects of major ingredients on the texture, structure and
In mass media social workers are often accused of either neglect for too long or interfering too soon in child protection cases in which children risk to come to harm. Given that the terrain of child protection has always been ambiguous and uncertain we wanted to explore the Swedish social workers’ own view on risk assessments. The aim of this study was to examine how social workers working with c
Health and emergency services aim to provide patients with urgent care according to an accessibility policy that is characterized by “proper service at the proper time and place” (Jordan et al. 2004; Murad 2007). Network analysis using geographical information system (GIS) applications has frequently been used in healthcare planning to investigate a population's accessibility to professional c
Stellar streams are made of stars that originate from globular clusters or dwarf satellite galaxies that have been disturbed by the gravitational pull from the galaxy they orbit. These stellar streams hold information about the history of the progenitor as well as information about the gravitational potential of the host galaxy. In this thesis we make use of the high resolution cosmological zoom s
In order to get a system with a very low damping, a positionservo has been provided with an inertia disc driven by spring transmission. The servo will therefore drive a mechanical oscillation unit. The motor is simulated as armature controlled by feeding back the tachogenerator signal to the existing motor which is field controlled. In a former examination work at the institution the transfer func
Moderate exercise is deemed beneficial for cognition due to increase in dopamine concentrations in the basal ganglia. Auditory white noise is beneficial for cognition, mainly for those with lower attentional ability, i.e. for those having lower tonic dopamine concentrations. For individuals with higher attention ability white noise can have a negative effect. In this thesis it was examined whether
