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Spinal muscle atrophy (SMA) is autosomal recessive and one of the most common inherited lethal diseases in childhood. The spectrum of symptoms of SMA is continuous and varies from neonatal death to progressive symmetrical muscle weakness first appearing in adulthood. The disease is produced by degeneration of spinal motor neurons and can be described in three or more categories: SMA I with onset o
Introduction. 60% of patients operated for colorectal liver metastases (CRLM) will develop recurrent disease and some may be candidates for a repeated liver resection. The study aimed to evaluate differences in intraoperative blood loss and complications comparing the primary and the repeated liver resection for metastases of colorectal cancer (CRC), as well as to evaluate differences in long-time
OBJECTIVE: To determine which factors increase the risk of large caesarean scar defects as assessed by transvaginal ultrasound. DESIGN: Observational cross-sectional study. SETTING: University Hospital. POPULATION: One hundred and eight women who had undergone one caesarean section. METHODS: Transvaginal ultrasound examination of the scar in the uterus 6-9 months after the caesarean. Published ult
Background: Early diagnosis of breast cancer treatment-related lymphedema (BCRL) is of great importance for longstanding treatment results. Tissue dielectric constant (TDC) and bioimpedance spectroscopy (BIS) both have a potential for early diagnosis, but have not been compared. Methods and Results: One hundred women, treated for breast cancer with breast surgery, axillary dissection, and radiothe
OBJECTIVE: Our objective was to investigate what impact 1 year of effective nocturnal continuous positive airway pressure (CPAP) treatment had on general and functional aspects of sexuality in male patients with a confirmed diagnosis of obstructive sleep apnoea (OSA). METHODS: Before and after 1 year of CPAP treatment, a total of 207 CPAP-compliant male patients (age 26-77) received a survey w
The purpose in this paper is to show how public procurement can be a driver ofinnovation. The purpose and point of departure when using public procurement as an instrument of innovation policy is always to solve societal and environmental problems, to satisfy human needs or to meet global challenges. The paper is aimed at everyone who is involved or interested in public procurement, and especially
Background: Circulating concentrations of biomarkers that are related to Vitamin status vary by factors such as diet, fortification, and supplement use. Published biomarker concentrations have also been influenced by the variation across laboratories, which complicates a comparison of results from different studies. Objective: We robustly and comprehensively assessed differences in biomarkers that
Inguinal hernia repair is one of the most common surgeries performed worldwide. With the success of modern hernia repair techniques, recurrence rates have significantly declined, with a lower incidence than the development of chronic postherniorrhaphy inguinal pain (CPIP). The avoidance of CPIP is arguably the most important clinical outcome and has the greatest impact on patient satisfaction, hea
The enzyme nitrogenase contains a complicated MoFe7CS9 cofactor with 35 possible broken- symmetry (BS) states. We have studied how the energies of these states depend on the geometry, the surrounding protein, the DFT functional and the basis set, studying the resting state, a one- electron reduced state and a protonated state. We find that the effect of the basis set is small, up to 11 kJ/mol. Lik
Background: The mechanically expandable Lotus Valve System is a fully repositionable and retrievable valve with an adaptive seal to minimize paravalvular leak (PVL). The aim of this study was to evaluate the short- and long-term safety and efficacy of the new device with focus on a new implantation technique to reduce the need for a permane
The first part of this paper aims at identifying the timing of famines in the Nordic countries since the middle ages. This is done by using qualitative famine reports from the literature since quantitative data on famines are scarce or non-existent, at least before the early modern period. We supplement the reports with climate data and price data. Our survey indicates that widespread famine was a
Popular Abstract in Swedish Svängningar i antalet individer hos en organismgrupp har under lång tid intresserat forskningen. Men sådana fluktuationer i populationer har inte bara ett vetenskapligt intresse. En ökad förståelse för fenomen som dessa kan hjälpa oss att fatta bättre beslut rörande mänskliga aktiviteter såsom fiske, jakt, skogsbruk och jordbruk och förhoppningsvis leda oss mot ett mer We are interested in the effect of harvesting on population fluctuations and for that purpose we develop and analyze an age-structured model where recruitment is a stochastic process and the adult segment of the population is harvested. When a constant annual harvest is taken the coefficient of variation of the adult population increases for most parameter values due to the age truncation effect,
REXEBIS is the charge breeder of the REX-ISOLDE postaccelerator. Radioactive 1+ ions produced at ISOLDE are accumulated, phase-space cooled and bunched in REXTRAP, and thereafter injected into the EBIS with an energy of up to 60 keV. The REXEBIS produced the first charge bred ions in August 2001 and has been running nearly non-stop from September to December 2001. It has delivered stable 39K10+ an
Recent years’ progress in the development of Continuous Glucose Monitors (CGM) has made rich well-sampled glucose data readily available. Reliable, frequent measurements are of outmost importance for the emerging closed-loop control of diabetic plasma glucose. However, these sensors do not measure the variable of primary interest - plasma glucose, but a delayed signal - the interstitial glucose. T
The use of a graphical system for the programming of industrial robots offers a number of advantages. Graphical systems employ an interface that is much easier to use. The resulting motion trajectories can be simulated and tested for collisions or singular points. Contemporary graphical systems use the geometry of the objects that are to be handled or processed in order to generate robot motion tr
This paper aims to discuss street art as new form of art and activism of uncomissioned and unsanctioned artifacts including paintings, murals and various kinds of stencils, posters, and stickers applied in any public surface. As Bengtsen (2014) has argued street art is a sociocultural practice, which is performative, ephemeral, and site specific. Street art has much to tell us about the dialectics
