Filetype
Background: Hip fractures are common in older individuals entailing considerable risk of morbidity and mortality. Instruments are needed to enhance risk stratification of hip fracture patients. There is limited knowledge of the role of biomarkers as risk prognosticators for mortality in hip fracture patients.Aims: We assessed how well two well known risk stratification tools performed in a cohort
BackgroundDementia is a syndrome, with a wide range of symptoms. It is important to have a timely diagnosis during the disease course to reduce the risk of medication errors, enable future care planning for the patient and their relatives thereby optimizing quality of life (QoL). For this reason, it is important to avoid a diagnosis of dementia not otherwise specified (DNOS) and instead obtain a d
PURPOSE: In the ENGOT-OV16/NOVA trial (ClinicalTrials.gov identifier: NCT01847274), maintenance therapy with niraparib, a poly(ADP-ribose) polymerase inhibitor, prolonged progression-free survival in patients with platinum-sensitive, recurrent ovarian cancer who had a response to their last platinum-based chemotherapy. The objective of the study was to assess the clinical benefit and patient-repor
Background Both AUDIT-C alcohol screening scores up to a year before surgery and clinical documentation of drinking over 2 drinks per day immediately prior to surgery (“documented drinking >2 d/d”) are associated with increased postoperative complications and health care utilization. The purpose of this study was to evaluate whether documented drinking >2 d/d contributed additional information abo
AbstractThe epidemiological association between diabetes and heart failure is well-established and the two entities areemerging as global threats, both individually and synergistically, to an aging population. The exploration of multipleproteins can shed light on pathophysiological pathways in both diabetes and cardiovascular disease. This canpossibly provide novel diagnostic, prognostic and hopef
Background: Mental health problems are prevalent among adolescents with severe obesity, but long-term mental health outcomes after adolescent bariatric surgery are not well known. We aimed to assess mental health outcomes over 5 years of follow-up after Roux-en-Y gastric bypass surgery in adolescents who participated in the Adolescent Morbid Obesity Surgery (AMOS) study. Methods: This was a non-ra
Land-Use Change and Terrestrial Predator–Prey Networks Land-use change, here defined as the conversion of one land-use type into another (e.g., forest to arable land), affects biodiversity and biotic interactions worldwide (Sala et al., 2000). Although there has been large regional variation in the extent of agricultural expansion and abandonment in Europe in the past 50 years (Rabbinge and van Di
Objectives: Clinical trials have demonstrated the efficacy of vedolizumab in inflammatory bowel disease (IBD). However, these findings may not reflect the clinical practice. Therefore, we aimed to describe a vedolizumab-treated patient population and assess long-term effectiveness. Materials and methods: Patients initiating vedolizumab between 1 June 2014 and 30 May 2015 were identified through th
This thesis studies the efforts made by society to achieve more efficient energy use in order to better utilise resources and lessen the stress on the environment. Despite the value to society promised by more efficient energy use, too few attempts are made at realising this value. One instrument available to governments in their efforts to stimulate efficiency schemes, is to encourage energy comp
Aims: The nuclear proliferation marker Ki67 assayed by immunohistochemistry has multiple potential uses in breast cancer, but an unacceptable level of interlaboratory variability has hampered its clinical utility. The International Ki67 in Breast Cancer Working Group has undertaken a systematic programme to determine whether Ki67 measurement can be analytically validated and standardised among lab
We present new algorithms for simulating Bose–Einstein correlations among final-state bosons in an event generator. The algorithms are all based on introducing Bose–Einstein correlations as a shift of final-state momenta among identical bosons, and differ only in the way energy and momentum conservation is ensured. The benefits and shortcomings of this approach, that may be viewed as a local rewei
Denna artikel innehåller en analys av samtliga rapporter från Statens offentliga utredningar (SOU), 1945-89. Analysen applicerar metoder inom digital humaniora och inkluderar forskning gjort i en Jupyterlabbmiljö som utvecklats på Humlab på Umeå universitet. Artikeln är ett resultat av forskningsprojektet Välfärdsstaten analyserad, som ämnar att digitalisera litteratur, arbetar med datasäkring av In 2015 the National Library of Sweden finished digitising all Governmental Official Reports (SOU) from 1922 to 1999. Traditionally, SOU reports – and work performed within different governmental committees – were tasked with preparing the Swedish government for apt and rational decision-making. The range of subjects covered by governmental committees and SOU reports basically includes every area
OBJECTIVE: To investigate the value of ultrasonographic data in predicting total knee replacement (TKR).DESIGN: Data from the Musculoskeletal Pain in Ullensaker study (MUST) was linked to the Norwegian Arthroplasty Register to form a 5-7 year prospective cohort study of 630 persons (69% women, mean (SD) age 64 (8.7) years). We examined the predictive power of ultrasound (US) features, i.e. osteoph
Abstract in UndeterminedContextThe key for effective problem prevention is detecting the causes of a problem that has occurred. Root cause analysis (RCA) is a structured investigation of the problem to identify which underlying causes need to be fixed. The RCA method consists of three steps: target problem detection, root cause detection, and corrective action innovation. Its results can help with
OBJECTIVE: To investigate the burden of ankylosing spondylitis (AS) in Spain, as baseline for economic evaluation of the use of biological agents. METHODS: A cross-sectional retrospective observational study was performed in 601 patients with AS in Spain, using a methodology developed in studies in the United Kingdom and Canada. Patients were mailed a questionnaire asking about their health-care c
We present an interactive online workshop for K-12 students, which aims in familiarizing students with core concepts of AI. The workshop consists of a variety of resources, inspired by inquiry-based learning techniques, of which we present in detail one module, centered around a browser-based game called “Gradient Descent”. This module introduces the mathematical concepts behind a gradient descent
OBJECTIVE: To investigate changes in socioeconomic inequalities in patient-related outcomes and pain medication use, following participation in a digital self-management intervention for osteoarthritis (OA) in Sweden.METHOD: Participants with hip/knee OA enrolled in the digital intervention were included. Self-reported outcomes collected were the numerical rating scale (NRS) pain, activity impairm
During graded exercise, systolic blood pressure (SBP) is expected to increase linearly, but other responses are observed. To date, a framework for algorithmic assessment of the shape of the SBP response is lacking, making its physiological and clinical relevance poorly understood. We aimed to algorithmically identify distinct SBP response shapes and analyze their association with clinical factors
KAP1 controls endogenous retroviruses in embryonic stem cells LETTERS KAP1 controls endogenous retroviruses in embryonic stem cells Helen M. Rowe1, Johan Jakobsson1{, Daniel Mesnard1, Jacques Rougemont1, Séverine Reynard1, Tugce Aktas2, Pierre V. Maillard1, Hillary Layard-Liesching1, Sonia Verp1, Julien Marquis1, François Spitz2, Daniel B. Constam1 & Didier Trono1 More than forty per cent of the
https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/publication_in_nature.pdf - 2026-07-09
Staff | Packaging Logistics Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store any personally identifiable informa
https://www.plog.lth.se/staff/ - 2026-07-09
