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Background: Long waiting times have been a significant problem in theSwedish health care system. A lack of matching of pathways of care has ledto long waiting times for patients, increasing medical risk and contributingtowards less effective capacity utilisation. There are different pathways into theelective healthcare system in Sweden, some via referral from a physician andothers via referral wri
Central nervous system (CNS) involvement is rare in patients with Hodgkin lymphoma (HL). Thus, the clinical features and outcomes are not well described. Cases of histologically confirmed CNS HL diagnosed between 1995 and 2015 were retrospectively identified in institutional (n = 7), national (n = 2), and cooperative group (n = 1) databases. We screened 30,781 patients with HL in our combined data
Background: Changes in the autonomic nervous system (ANS) tone are present before, during, and after episodes of atrial fibrillation (AF). Atrial fibrillatory rate (AFR, the inverse of the atrial cycle length) has been used as a surrogate marker for local refractoriness and is a key characteristic of the fibrillatory process in patients with AF. Aim of this study is to assess changes in AFR, as an
The aim of the study was to investigate the feasibility of optimizing prophylactic dosing of factor VIII by the use of individual pharmacokinetic data. Twenty-one patients were enrolled in a randomized cross-over study on standard dosage regimens vs. dosing according to pharmacokinetic principles. The study period was 2 x 6 months. Using single-dose pharmacokinetic data for each patient, plasma fa
Flame structures, blowout limits and emissions of swirlstabilized premixed methane-air flames were studied experimentally in a small atmospheric combustor rig. Combustion sections with rectangular cross section (30mm by 40mm) and circular cross section (inner diameter = 39mm) were used to investigate effects of combustor geometry on the flame's performance. Flame structures and instabilities were
Objective: To describe beliefs about health and illness among foreign-born people with diabetic foot ulcers that might affect selfreported self-care and health-care seeking and to study whether there are dissimilarities related to origin. Method: Qualitative descriptive study. Semi-structured interviews with people aged 38-86 years; 13 born in European and 13 in non-European countries (all except
INTRODUCTION: Several lines of evidence indicate that increased inflammation is associated with Post-Traumatic Stress Disorder (PTSD). We have previously reported that peripheral inflammatory markers are significantly higher in combat-exposed veterans with than without PTSD. This study was designed to replicate these findings in a new study cohort using the same population and recruitment strategi
Monitoring is science keeping our thumb on the pulse of the environment to detect any changes of concern for societies. Basic science is the question-driven search for fundamental processes and mechanisms. Given the firm root of monitoring in human interests and needs, basic sciences have often been regarded as scientifically "purer"-particularly within university-based research communities. We ar
Objective: The risk of certain psychiatric disorders is elevated among immigrants. To date, no population studies on immigrant health have addressed eating disorders. We examined whether risk of eating disorders in first- and second-generation immigrants differs from native-born Danes and Swedes. Method: All individuals born 1984–2002 (Danish cohort) and 1989–1999 (Swedish cohort) and residing in
OBJECTIVE: To investigate the long-term safety and tolerability of a once-daily, dual-release hydrocortisone (DR-HC) tablet as oral glucocorticoid replacement therapy in patients with primary adrenal insufficiency (AI).DESIGN: Prospective, open-label, multicenter, 5-year extension study of DR-HC conducted at five university clinics in Sweden.METHODS: Seventy-one adult patients diagnosed with prima
The aim of this study was to identify molecules that trigger complement activation in rheumatic joints. C4d, the final cleavage product of C4 activation, is found in the diseased joint and can bind covalently to complement-activating molecules. By using a highly specific Ab against a cleavage neoepitope in C4d, several molecules that were specifically bound to C4d were identified from pooled synov
Background: Since the introduction of high-sensitivity troponin assays a greater proportion of atrial fibrillation (AF) patients present with dynamic troponin elevations. We hypothesize that significant coronary artery disease (CAD) causes relative ischemia in the setting of a rapid heart rate resulting in dynamic troponin elevation. The aim of this study was to examine if patients without known C
Why do some forests produce biomass more efficiently than others? Variations in Carbon Use Efficiency (CUE: total Net Primary Production (NPP)/ Gross Primary Production (GPP)) may be due to changes in wood residence time (Biomass/NPPwood), temperature, or soil nutrient status. We tested these hypotheses in 14, one ha plots across Amazonian and Andean forests where we measured most key components o
The installation is based on two elements, a re-used tape recorder and a pair of aged wooden planks. The planks are mounted to form a table on which the tape recorder is placed. The sound from the tape recorder is based on field recordings from the area around the municipality Taivalkoski in Northeastern Finland. The tape recorder has formerly been used at The Department of Ethnology at Lund Univ
Zinc (Zn) is an essential micronutrient but may become toxic when present in excess. In Zn-contaminated environments, trees can be protected from Zn toxicity by their root-associated micro-organisms, in particular ectomycorrhizal fungi. The mechanisms of cellular Zn homeostasis in ectomycorrhizal fungi and their contribution to the host tree's Zn status are however not yet fully understood. The ai
The revision of Pilosella presented by the author in 2001 is here updated with new records and taxa, and recent international advancements in the field are briefly presented and discussed. The taxonomy of the previous revision, based on the "genotypic cluster species concept" of Mallet and the principles that species should be circumscribed as groups of individuals whose intermediates are rare and
AIMS: To assess the efficacy of the 2nd generation Cryoballoon for pulmonary vein isolation (PVI) in patients with persistent atrial fibrillation (PersAF), and to compare it to patients with paroxysmal atrial fibrillation (PAF).METHODS: The outcome (arrhythmia recurrence at 12 months) was prospectively assessed in patients with PersAF(n = 77) and compared to that in patients with PAF(n = 62), who
Material traceability is an important part of industrial manufacturing, especially in systems where quality, reliability, and documentation requirements are high. In many companies, traceability is often assumed to already exist because there are certificates, ERP systems, production documents, and established routines. However, during this study, it became clear that having information available
This study explored how young Swedish adults aged 20–30 describe and understand experiences of weight-based bullying during their school years, as well as their ways of coping. A qualitative design using semi-structured interviews was employed. The sample consisted of nine young adults with a mean age of 24.7 years, including two males and seven females. All participants had lived with overweight
