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Burkitt lymphoma (BL) is a rare, aggressive disorder constituting 1% of all non-Hodgkin lymphoma. Diffuse large B-cell lymphoma (DLBCL) is more common, accounting for 30% of malignant lymphoma. Standard treatment for adult BL and for certain subgroups of patients with DLBCL remains to be defined due to paucity of randomised trials performed. The focus in this thesis lies on the effect of prognosti
Popular Abstract in Swedish Det blir allt vanligare att man ersätter förlorade och skadade kroppsdelar med ett biomaterial (vanligtvis ett metall eller polymer implantat). Exempel på vanliga användningsområden är; suturer, kärl, hjärtklaffar, pacemakers, katetrar, ledproteser, fixationsskruvar för skelett och konstgjorda tänder samt kapslar för långsam frisättning av medicin. Trots det rutinmässigThe biological response to different implanted biomaterials vary. The relative importance of factors in the material and host for this variation are at present incompletely known. The variation in the cellular response to specific proteins and the rapid adsorption of proteins to surfaces exposed to biological environments has created the hypothesis that the cellular interactions with biomaterials
Popular Abstract in Swedish Avhandlingen handlar om lungornas funktion hos för tidigt födda (prematura) barn med brist på surfaktant, ett ämne som normalt ska finnas i lungorna, och hur lungfunktionen hos sådana barn kan förbättras genom tillförsel av det saknade ämnet utifrån. I avhandlingen har också använts en djurmodell (för tidigt födda lamm) för att studera hur konstgjord andning vid födelseThe thesis investigates lung function and the effects of rescue surfactant treatment in mechanically ventilated preterm human infants with respiratory distress syndrome (RDS), and the effects of ventilation at birth on the response to surfactant supplementation in preterm lambs. To assess lung function, the author recorded static pressure-volume (P-V) curves during passive deflation from total lun
Background and Purpose - Aortic valve stenosis may lead to atrial and ventricular remodeling, predisposes to atrial fibrillation, and may also be an independent risk factor of ischemic stroke. However, information on stroke rates among persons with aortic valve stenosis are sparse. We aimed to determine the incidence rates and relative risks of ischemic stroke in individuals with diagnosed aortic
The paleobiogeography of Early–Middle Devonian (Pragian–Eifelian) brachiopods from West Gondwana was assessed to determine any potential controls (regional climatic differences or global eustasy) that may have driven bioregionalization. The Pragian–Eifelian interval of West Gondwana was examined because work by previous authors suggested that this was a period when regionally extensive areas of pr
Background: Current equations for estimated glomerular filtration rate (eGFR) that use serum creatinine or cystatin C incorporate age, sex, and race to estimate measured GFR. However, race in eGFR equations is a social and not a biologic construct.Methods: We developed new eGFR equations without race using data from two development data sets: 10 studies (8254 participants, 31.5% Black) for serum c
Objective: Endovascular aneurysm repair (EVAR) has been extensively study regarding elective and ruptured abdominal aortic aneurysm (AAA) repair. However, much less is known about EVAR of symptomatic nonruptured AAA, especially concerning the long-term results. The aim of this study was to assess the outcomes of EVAR of symptomatic AAA compared with asymptomatic AAA at a tertiary center using a si
Surrogate measures of safety (SMoS) are meant to function as tools to investigate traffic safety. The term surrogate indicates that these measures do not rely on crash data; instead, they focus on identifying safety critical events (or near-crashes) in traffic, which can be used as an alternative to crash records. The overall aim of this thesis is to explore which SMoS are suitable when analysing
Recent advances in the digital detector technology have paved the way for modalities such as two-dimensional digital mammography (DM) and three-dimensional breast tomosynthesis (BT). In this work, experimental studies were conducted to investigate the influence of reducing the average glandular dose (AGD) on detection of simulated lesions in DM and to compare the diagnostic accuracy of BT and DM.
Unusually high CO2 concentrations were frequently observed during stable nights in late summer 2006 at the CarboEurope-Integrated Project (CEIP) forest site in Norunda, Sweden. Mean CO2 concentrations in the layer below the height of the eddy-covariance measurement system at 30 m reached up to 500 mu mol mol(-1) and large vertical and horizontal gradients occurred, leading to very large advective
Abstract The breeding season of the natterjack toad (Bufo calamita Laurenti 1768), a „prolonged breeder“, lasts up to three months in southern Sweden. However, not all reproducing individuals are present at the breeding sites during the full time span. Thus, some populations can be sub-divided into temporally isolated subpopulations using earlier or later periods of the season for reproduction. T
PURPOSE: To evaluate the outcomes of preserving the internal iliac artery (IIA) with iliac branched devices (IBDs) during acute endovascular repair of ruptured aortoiliac aneurysms.MATERIAL AND METHODS: This is a multicenter retrospective review of all consecutive patients undergoing acute endovascular repair of ruptured aortoiliac aneurysm with an IBD at 8 aortic centers between December 2012 and
The aim of this study was to evaluate the degree of joint fusion and bone formation in dogs undergoing atlantoaxial arthrodesis after removal of articular cartilage associated or not to implant homogenous or autogenous cancellous bone. Twelve dogs, weighing between 8 and 12kg were randomly divided into three groups. Group I (GI) performed only the removal of joint cartilage and joint immobilizatio
The evaluation of satellite precipitation products (SPPs) at regional and local scales is essential in improving satellite-based algorithms and sensors, as well as in providing valuable guidance when choosing alternative precipitation data for the local community. The Tropical Rainfall Measuring Mission (TRMM) has made significant contributions to the development of various SPPs since its launch i
BACKGROUND: Beneficial effects from practising a Paleolithic diet as compared to a diabetes diet on weight, waist circumference, satiety, leptin, HbA1c and glucose control in randomised controlled trial participants with type 2 diabetes could be due to lower leptin resistance. Support for this hypothesis comes from an in vitro experiment that showed that digested wheat gluten, which is excluded fr
TEDDY Årsrapport 2014 1 Årsrapport 2014 TEDDY - Omgivningsfaktorer för typ 1-diabetes och celiaki hos barn Ystad Malmö Helsingborg Kristianstad TEDDY-lab Malmö Simrishamn TEDDY Årsrapport 2014 2 Innehållsförteckning 1. Sammanfattning – ”TEDDY har ett resultat” 2. Bakgrund TEDDY-studien 3. Typ 1-diabetes - är en sjukdom i två steg 4. Glutenintolerans – celiaki - utvecklas också i två steg 5. TEDDY-
https://www.teddy.lu.se/sites/teddy.lu.se/files/2014_teddy_arsrapport.pdf - 2026-07-16
1 Årsrapport 2019 TEDDY - Omgivningsfaktorer för utveckling av autoimmun (typ 1) diabetes och celiaki hos barn 2 Innehållsförteckning 1. Vad har TEDDY kommit fram till om autoimmun (typ 1) diabetes under 2019? 2. Vad har TEDDY kommit fram till om celiaki (glutenintolerans) under 2019? 3. TEDDY studiens organisation Alla fyra deltagande länder Skåne 4. Besök på TEDDY mottagningarna 5. Barn med auto
https://www.teddy.lu.se/sites/teddy.lu.se/files/2019_teddy_arsrapport.pdf - 2026-07-16
Regler forskarutbildning Medicinska fakulteten Regler för utbildning på forskarnivå MEDICINSKA FAKULTETEN | LUNDS UNIVERSITET | GÄLLER FRÅN 1 JANUARI 2019 Sida 1 av 44 Postadress Box 117 221 00 Lund Besöksadress BMC Sölvegatan 19 Telefon 046-222 00 00 E-post info@med.lu.se Webbadress www.medicin.lu.se Forskarutbildningsnämnden BESLUT Diarienummer U 2023/595 Datum 2023-12-12 Regler för utbildning p
Microsoft Word - Simoa_Template inftrastructure report 211013.docx Multipark infrastructure report form 2021 SIMOA ANALYZER Shorena Janelidze Short description of the infrastructure. Quanterix SR-X Ultra-Sensitive Biomarker Detection System The Simoa is particularly useful for measurements of biomarkers at ultra-low levels. The approach is based on the counting of thousands of single immunocomplex
https://www.multipark.lu.se/sites/multipark.lu.se/files/2021-10/Simoa_inftrastructure%20report%20211013.pdf - 2026-07-16
