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Indications for and the results of carotid endarterectomy in symptomatic and asymptomatic carotid artery stenosis are reviewed. The main indication for carotid endarterectomy is symptomatic stenosis of a carotid artery with >70 percent lumen reduction according to the NASCET method, or >85 percent lumen reduction according to the ECST method. The operation should ideally be performed within two we
Mitochondrial diseases, predominantly mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS), may occasionally underlie or coincide with ischemic stroke (IS) in young and middle-aged individuals. We searched for undiagnosed patients with MELAS in a target subpopulation of unselected young IS patients enrolled in the Stroke in Young Fabry Patients study (sifap1). Among t
To determine if PET reporting criteria for the Response Adapted Treatment in Hodgkin Lymphoma (RATHL) trial could enable satisfactory agreement to be reached between 'core' laboratories operating in different countries. Four centres reported scans from 50 patients with stage II-IV HL, acquired before and after two cycles of Adriamycin/bleomycin/vinblastine/dacarbazine. A five-point scale was used
Organization of the human embryonic ventral mesencephalon Gene Expression Patterns 9 (2009) 555–561 Contents lists available at ScienceDirect Gene Expression Patterns journal homepage: www.elsevier .com/locate /gep Organization of the human embryonic ventral mesencephalon Jenny Nelander, Josephine B. Hebsgaard, Malin Parmar * Department of Experimental Medical Science and Lund Strategic Center for
https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/nelander_et_al_2009.pdf - 2026-07-25
Background: Mild to moderate cognitive impairment is common amongst long-term survivors of cardiac arrest. In the Target Temperature Management trial (TTM-trial) comatose survivors were randomized to 33 degrees C or 36 degrees C temperature control for 24 hours after cardiac arrest and the effects on survival and neurological outcome assessed. This protocol describes a sub-study of the TTM-trial i
Popular Abstract in Swedish Sambanden mellan kostens sammansättning och risk för hjärt-kärlsjukdom är i många fall oklara. En kost rik på fleromättade fettsyror har ansetts kunna ge skydd mot hjärt-kärlsjukdom, men resultaten från olika studier är motstridiga. En anledning till detta kan vara för att man inte har tagit hänsyn till de genetiska skillnader som finns mellan individer. Omega-3 och oIn previous studies, a high quality diet has been associated with a reduced risk of cardiovascular disease (CVD) compared to a low diet quality, and specific “healthy” diet components, such as polyunsaturated fatty acids (PUFAs), have been hypothesized to reduce the risk of CVD. However, results from epidemiological studies have been conflicting. This may be due to individuals having varied geneti
BACKGROUND AND PURPOSE: Although there have been numerous publications on lumbar disc herniation (LDH) treated surgically, there has been little interest in sex differences. It has been shown in many studies that sex differences may be important in certain diseases. We therefore reviewed consecutive register material from one institution for possible gender differences in pre- and postoperative pa
Children’s understanding of death, bereavement and grief develop through socialisation where picture books also may play a role. The study explores how children’s picture books published in China (2010–2024), communicated themes of death, bereavement and grief. A systematic search identified 321 relevant books, of which 47 met the inclusion criteria and were analysed using both descriptive and a B
We aimed to study psychological health, as approximated by the use of psychotropic drugs, in a population diagnosed and surgically treated for carpal tunnel syndrome (CTS) or ulnar nerve entrapment (UNE), or both, also considering the demographic and socioeconomic factors of the individuals. Linking data from five large national registers, use of psychotropics (at least one dispensation during the
Division of Chemical Physics, Department of Chemistry Lab. Name: Ultra Contact persons : Arkady Yartsev (arkady.yartsev@chemphys.lu.se), Condition for using: hire the tool technician to run the experiment / collaborative project Equipment: Femtosecond laser (Pharos, Light conversion), 1030 nm, 1-600 000 Hz, 200 fs (http://www.lightcon.com/products/product.php?ID=28) NOPA second harmonic (Orpheus,
https://www.nano.lu.se/sites/nano.lu.se/files/lncl_equipment_list2018.docx - 2026-07-25
Background Patients with severe asthma are often inadequately controlled on existing anti-asthma therapy, constituting an unmet clinical need. Objective This randomized, double-blind, placebo-controlled trial evaluated the ability of omalizumab, a humanized monoclonal anti-IgE antibody, to improve disease control sufficiently to enable inhaled corticosteroid reduction in patients with severe aller
Fluorescence microscopy is introduced as a low cost quality control process for nanoimprint lithography. To depict imprinted structures down to 1 mum lateral size and to detect residues down to 100 nm lateral size, the standard printable polymer mr-18000 is labelled with less than 0.1 wt.% fluorescent dye. Three different types of stamps are used to determine the dependence of the shape and size o
Popular Abstract in Swedish Aggressiva lymfom utgör en undergrupp av en typ av elakartade (maligna) tumörer, maligna lymfom. Cellerna i dessa tumörer utgår från en typ av vita blodkroppar, lymfocyter, vilka har en central roll i kroppens immunförsvar. Maligna lymfom utgör ca 4% av alla fall av elakartade tumörer i Sverige, vilket motsvarar ca 1700 nya fall per år. I västvärlden ökar dock antalet fAggressive lymphoma is a rapidly growing tumour of lymphocyte origin, potentially curable with chemotherapy. In a trial by the Nordic Lymphoma Group, 405 patients with aggressive lymphoma were included, and randomised to receive either the standard chemotherapy regimen, CHOP, or a weekly multidrug regimen, MACOP-B. In this trial, MACOP-B was not superior in terms of response, failure-free or overa
Several animal studies indicate that mercury is a male reproductive toxicant, but human studies are few and contradictory. We examined semen characteristics and serum levels of reproductive hormones in relation to environmental exposure to mercury. Blood and semen samples were collected from 529 male partners of pregnant women living in Greenland, Poland and Ukraine between May 2002 and February 2
Purpose Young adults (18–24 years) frequently report poorer health care access and experience than older adults. We aimed to investigate how differences between young and older adults vary across 11 high-income countries. Methods A total of 20,045 participants from 11 high-income countries (i.e., Australia, Canada, France, Germany, the Netherlands, New Zealand, Norway, Sweden, Switzerland, United
BACKGROUND/AIM: Cancer, one of the leading causes of mortality in the world, imposes a substantial economic burden on each society, including Serbia. The aim of this study was to evaluate the major cancer cost drivers in Serbia.METHODS: A retrospective, in-depth, bottom-up analysis of two combined databases was performed in order to quantify relevant costs. End-of-life data were obtained from pati
Background Care of old people with multimorbidity living at home is often fragmented with lack of coordination and information exchange between health care professionals, the elderly and their relatives. This paper describes the protocol of a randomised, controlled study, which aims to compare the efficacy of caring for older people with multimorbidity and three or more hospital admissions in the
Popular Abstract in Swedish SAMMANFATTNING (SUMMARY IN SWEDISH) Jod är nödvändigt för utvecklingen och hälsan hos alla högre djur inklusive männi-ska, men det är ett relativt sällsynt grundämne. Man får i sig jod via kosten och det högsta jodinnehållet har fisk och skaldjur eftersom havssalt innehåller jod. Jod finns även i mejeriprodukter och i mindre mängder i grönsaker, men jodinnehållet i dessABSTRACT Background: Iodine is essential for development and growth as a constituent in thyroid hormones. Biological mechanisms for iodide uptake and concentration are very important, espe-cially as iodine is a relatively scarce element. Active iodide transport into thyroid fol-licular cells is mediated by the sodium/iodide symporter (NIS), powered by Na+/K+-ATPase. NIS is expressed also in extra
This paper is a report on the European Food Science Day (Brussels, 18 November 2009, organized by the CommNet network of food science communicators) and its outcomes. The article presents FP 7 as a key funding mechanism in European food and nutrition research and it puts research in this sector in a socio-economic context. The article then reviews the specific activities of several EU-funded proje
IntroductionChanges in long-term survival after stroke at the population level are incompletely characterized, particularly using recent data and stratified by stroke type.Patients and MethodsThis nationwide, register-based cohort study used data from the Swedish Stroke Register (Riksstroke) and the Swedish Causes of Death Register. Adults (≥18 years) hospitalized with ischemic stroke or intracere
