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Background: Registries are important in rare disease research. The Anorectal Malformation Network (ARM-Net) registry is a well-established European patient registry collecting demographic, clinical, and functional outcome data. We assessed the quality of this registry through review of the structure, data elements, collected data, and user experience. Material and methods: Design and data elements
Background: High gluten and low dietary fiber in pregnancy intake is associated with an increased risk of celiac disease (CeD) in the child. Early life higher dietary quality is suggested to reduce the subsequent risk of CeD. Objectives: The aim was to investigate associations of pregnancy dietary quality and diversity with child risk of CeD. Methods: In The Norwegian Mother, Father and Child Coho
Popular Abstract in Swedish ”Att leva med cancer som äldre, livskvalitet och upplevelse av mening” Cancer drabbar företrädesvis äldre personer och är en sjukdom som blir vanligare i takt med det stigande antalet äldre i befolkningen. Cancer hos äldre innebär en komplex situation eftersom åldrandet är präglat av stora individuella förändringar med ökande sjuklighet, nedsatt funktionell förmåga, föThe overall aim of this thesis was to investigate quality of life in people aged 75 and older with cancer in relation to age, gender, presence and type of complaints, comorbidity, living conditions, perceived economic situation, sense of coherence, receiving help for daily living and social resources. The aim was also to investigate older people’s experiences and the meaning of living with cancer
Background: The goal of clinical computed tomography (CT) is to produce images of diagnostic quality using the lowest possible radiation exposure. Degradation of image quality, with increased image noise and reduced spatial resolution, is a major limitation for radiation dose reduction in CT. This can be counteracted with new post-processing image filters and iterative reconstruction (IR) algorith
Abstract in Danish Denne afhandling handler om livskvalitet hos ældre mennesker med kræft. Risikoen for at få kræft stiger med alderen, og til trods for at de fleste mennesker, der får kræft er ældre, har forskning i hvordan ældre lever med en kræftsygdom været yderst begrænset. Viden om hvordan ældre mennesker oplever det at få en kræftdiagnose og hvordan de lever med sygdommen er en forudsætningOver the coming decades, the numbers of elderly will increase, and through improved lifestyles and better treatment longevity has increased, and with it, the risk of contracting cancer. How elderly people live with cancer has until now attracted limited research. The overall aim of this thesis was to investigate the QoL of elderly persons from the time of a cancer diagnosis through the following s
Understanding the quality of eye-tracking recordings, often characterized using accuracy, precision, and data loss, is crucial for the interpretation of eye tracking data. Eye-tracking data quality can furthermore place fundamental limits on what studies can be conducted with an eye tracker, and one may be required to report eye-tracking data quality when publishing a study. However, how does one
P fertilizers are made from phosphate rock, which is a finite resource. It was added to the EU list of critical raw materials in 2014. The phosphorus in P fertilizers could potentially be substituted by a substance called struvite, which can be recovered from sewage sludge. In 2019, the EU updated and included struvite into fertilizer regulation 1009/2019 which made distribution of struvite possib
Aim. This paper reports a study comparing the socio-demographic data, quality of life (QoL) and symptoms of older people living at home with and without help. Background. Despite growing numbers of older people worldwide, little is know about the differences between older people receiving help to live at home and those not receiving this, especially as regards QoL and symptoms. Not only symptoms b
Background: Overall survival for patients with small intestinal neuroendocrine tumours (siNETs) is long, even with metastatic disease, making quality of life issues relevant. The impact of surgery on quality of life is not known. We investigated determinants of health-related quality of life in patients who had undergone surgery for a siNET. Methods: Patients operated for a siNET between 1998 and
An increase in demand for fresh vegetables resulted in an increased production of minimally processed, ready-to-eat salad in Sweden. That also brought new food safety challenges that are yet to be addressed. To assess whether ready-to-eat leafy green vegetables present a threat in terms food borne outbreaks, aerobic bacteria, as well as bacteria belonging to the Enterobacteriaceae family were rec
The process of selecting requirements for a release of a software product is challenging as the decision-making is based on uncertain predictions of issues such as market value and development cost. This paper presents a method aimed at supporting software product development organisations in the identification of process improvement proposals to increase requirements selection quality. The method
Patient-reported health status questionnaires intend to assess illness and therapy from the patients' perspective. To provide fair and valid assessments, they should be equally relevant to major subsets of respondents. Furthermore, disease-specific measures are assumed to be perceived as more relevant than generic ones. This study assessed these assumptions among people with Parkinson's disease. C
Background: Approximately 50% of all patients undergoing esophagectomy experience complications. This paper estimates the costs due to complications after esophagectomy in a Swedish context. Material and methods: The Swedish National Register for Esophageal and Gastric Cancer (NREV) and the Healthcare Consumption Register in Region Skåne (RSVD) were crossmatched for patients undergoing esophagecto
Several methods have been developed to predict effects of amino acid substitutions on protein stability. Benchmark datasets are essential for method training and testing and have numerous requirements including that the data is representative for the investigated phenomenon. Available machine learning algorithms for variant stability have all been trained with ProTherm data. We noticed a number of
P>Aims To determine health-related quality of life (HRQL) in diabetic and non-diabetic patients with carpal tunnel syndrome (CTS) before and after surgical treatment. Methods In a prospective study, 35 consecutive diabetic patients with CTS were age and gender matched with 31 non-diabetic patients with idiopathic CTS. At baseline (preoperatively), 6, 12 and 52 weeks after surgical carpal tunnel re
Background. Over five billion people worldwide lack access to safe and affordable surgery and anesthesia care when required. There is a critical unmet need for surgical care, especially in low-income and middle-income countries (LMICs). The shortage of surgical providers is one of the most influential barriers to receiving surgical care, and the maldistribution is aggravated by doctors emigrating
Background: Patients with Lewy body dementias (LBD) have a complex clinical picture. With no prevention or cure, management focuses around symptomatic relief, however pharmacological and non-pharmacological options have been inadequately investigated. Moreover, the understanding of survival, prognostic factors and impact of the diagnosis in an already ageing and comorbid population is limited. Eve
