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Everyday life after a radical prostatectomy – A qualitative study of men under 65 years of age

Purpose The purpose of this study was to illuminate how men under 65 years of age experience their everyday Life one year or more after a radical prostatectomy for localised prostate cancer. Method Interviews with 19 men aged under 65 were performed 12–18 months after their radical prostatectomy. The interviews were analysed using a thematic content analysis. Results The analysis of the interviews

Wetland areas' direct contributions to residents' well-being entitle them to high cultural ecosystem values

Wetlands in urban areas will be crucial to counteract the effects of climate change, for example, by improving flood protection and regulating local climate. To gain acceptance for larger-scale creation of wetlands, total values must be identified and revealed. Provisioning and regulating ecosystem services can be described as the quantitative effect, but cultural ecosystem services require other

Serotonin and Neuropeptides in Blood From Episodic and Chronic Migraine and Cluster Headache Patients in Case-Control and Case-Crossover Settings : A Systematic Review and Meta-Analysis

Objective: The aim of this systematic review and meta-analysis (SR-MA) was to identify signaling molecule profiles and blood-derived biomarkers in migraine and cluster headache (CH) patients. Background: Currently no migraine and CH valid biomarkers are available. Blood tests based on biomarker profiles have been used to gather information about the nervous system. Such tests have not yet been est

A Computational Model of Wason's Selection Task

We apply an algorithmic learning model of inquiry to model reasoning carried by experimental subjects in Wason's _Selection Task_ that represents reasoning in the task as computation of a decision tree that supervenes on (partial) semantic representations. We argue that the resulting model improves on previous probabilistic (Bayesian) and pragmatic (Relevance theory) models of the task. In particu

Will this hemodynamically unstable patient respond to a bolus of intravenous fluids?

IMPORTANCE Fluid overload occurring as a consequence of overly aggressive fluid resuscitation may adversely affect outcome in hemodynamically unstable critically ill patients. Therefore, following the initial fluid resuscitation, it is important to identify which patients will benefit from further fluid administration. OBJECTIVE To identify predictors of fluid responsiveness in hemodynamically uns

Use and productivity of contemporary, multidisciplinary Big Science

The use of very large instrumentation, usually called Big Science, became an important part of Western science systems after World War II, with nuclear and particle physics at the center. Throughout the Cold War era, however, science policy priorities and objectives gradually shifted and in parallel therewith, new uses of Big Science emerged that were oriented to the study of materials and later a

Optimizing joint function : new knowledge and novel tools and treatments

Progressive joint destruction resulting from intra-articular bleeding is the major morbidity affecting patients with haemophilia (PWH), particularly those with inhibitors. Advances in understanding the detrimental processes set in motion by the exposure of joints to bleeding have shaped current management methods. However, to achieve optimal joint health in PWH, in addition to achieving haemostasi

Treatment for acute anterior cruciate ligament tear: five year outcome of randomised trial. : Five year outcome of randomised trial

Objective To compare, in young active adults with an acute anterior cruciate ligament (ACL) tear, the mid-term (five year) patient reported and radiographic outcomes between those treated with rehabilitation plus early ACL reconstruction and those treated with rehabilitation and optional delayed ACL reconstruction. Design Extended follow-up of prospective randomised controlled trial. Setting Ortho

Status of e-learning implementation to enhance learning in Tanzanian university institutions

This study examines the current e-learning implementation in Tanzanian universities, highlighting the challenges and opportunities associated with its utilisation. Data was collected from 610 respondents, including e-learning support staff, lecturers, and students from five selected universities through questionnaires and interviews. The findings reveal that universities in Tanzania still face imp

Caesarean section rates in public vs private hospitals in Europe : a systematic review and meta-analysis using the Robson ten group classification system

INTRODUCTION: Since the last two decades, there has been a dramatic rise in caesarean sections (CS) throughout the world. This increase has been seen even in Europe, where rates vary significantly from 17% in Northern Europe to 56% in the South. Although, CS can be a lifesaving intervention when medically necessary, non-essential CS are associated with short- and long-term complications for both t

Quality issues in harvested rainwater in arid and semi-arid Loess Plateau of northern China

Loess soils cover vast areas in the arid and semi-arid regions of northern China. Due to the lack of reliable surface water and ground-water, rainwater harvesting has played a prominent role in farmers' domestic usage and agricultural irrigation. An economical arid valid type of water storage cistern with optimum design of components has been introduced to rural areas in the Loess Plateau. Differe

Unveiling Psychedelics : One of the Most Meaningful Events in Life Associated with Improved Well-Being in Swedish Users

In the midst of growing research and societal discourse on psychedelic substances, a consistent finding is reported: A majority of users report profound personal meaning from their experiences. This pioneering study in Sweden, a nation renowned for its strict drug policies, sought to quantify the extent of reported meaningfulness among Swedish psychedelic users. Results revealed that a majority of

Impact of mono- or multitherapy on ocular surface health and quality of life after 5 years of follow-up in the Glaucoma Intensive Treatment Study (GITS)

Aim: To evaluate the impact of initial mono- versus multitherapy on the ocular surface and related quality of life after 5 years follow-up in the Glaucoma Intensive Treatment Study (GITS). Method: The study included patients with primary open-angle glaucoma and pseudoexfoliation glaucoma who completed 5-year follow-up in GITS. Assessment of ocular surface disease (OSD) symptoms was done using a Sw

Does active transport create a win-win situation for environmental and human health? The moderating effect of leisure and tourism activity

Although active transport contributes to environmental and human health, only limited research has been conducted on what makes people participate in active transport in tourism-related contexts. To fill this gap, research was conducted on theoretically conceptualized relationships between pro-social behavior on active transport, air quality, climate change mitigation, and health with a moderator

Long-term results of cytoreduction and HIPEC followed by systemic chemotherapy

Cytoreduction followed by hyperthermic intraperitoneal chemotherapy is a treatment option for peritoneal surface malignancies in The Netherlands. This treatment has been available for more than 10 years. Therefore, long-term results on survival and quality of life can now be studied. With these results, the true long-term benefits of this new management strategy can be determined.

The need for nonuniform risk acceptability across climate change scenarios

Climate change risk assessment studies focus on identifying and analyzing different risks considering several climate change scenarios and on evaluating the cost-effectiveness of different adaptation measures. However, risk acceptability is often not reflected on in the context of climate change risk studies. Noting that the different climate change scenarios depict drastically contrasting images

Vagus nerve stimulation in 15 children with therapy resistant epilepsy; its impact on cognition, quality of life, behaviour and mood.

PURPOSE: Vagus nerve stimulation (VNS) is a neurophysiologic treatment for patients with refractory epilepsy. There is growing evidence of additional quality of life (QOL) benefits of VNS. We report the effects of VNS on seizure frequency and severity and how these changes are related to cognitive abilities, QOL, behaviour and mood in 15 children with medically refractory and for surgery not eligi