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Short, medium, and long deferral of umbilical cord clamping compared with umbilical cord milking and immediate clamping at preterm birth : a systematic review and network meta-analysis with individual participant data

Background: Deferred (also known as delayed) cord clamping can improve survival of infants born preterm (before 37 weeks of gestation), but the optimal duration of deferral remains unclear. We conducted a systematic review and individual participant data network meta-analysis with the aim of comparing the effectiveness of umbilical cord clamping strategies with different timings of clamping or wit

Expected features of the course leader in the rehabilitation healthcare professionals’ higher education : A qualitative study on students’ perspectives

Course leaders in rehabilitation healthcare professionals’ higher education face challenges stemming from multi-disciplinarity and the co-existence of different stakeholders. So far, the literature mainly attributed to course leaders’ managerial tasks, neglecting other fundamental transversal skills. Students represent an essential source of information for understanding the expected characteristi

Smart home technology to support engagement in everyday activities while ageing: A focus group study with current and future generations of older adults

Despite the potential of smart home technologies (SHT) to support everyday activities, the implementation rate of such technology in the homes of older adults remains low. The overall aim of this study was to explore factors involved in the decision-making process in adopting SHT among current and future generations of older adults. We also aimed to identify and understand barriers and facilitator

Dynamic glucose enhanced imaging using direct water saturation

PURPOSE: Dynamic glucose enhanced (DGE) MRI studies employ CEST or spin lock (CESL) to study glucose uptake. Currently, these methods are hampered by low effect size and sensitivity to motion. To overcome this, we propose to utilize exchange-based linewidth (LW) broadening of the direct water saturation (DS) curve of the water saturation spectrum (Z-spectrum) during and after glucose infusion (DS-

Multicentre, national, investigator-initiated, randomised, parallel-group, register-based superiority trial to compare extended ECG monitoring versus standard ECG monitoring in elderly patients with ischaemic stroke or transient ischaemic attack and the effect on stroke, death and intracerebral bleeding : the AF SPICE protocol

Introduction Atrial fibrillation (AF) is a major risk factor for ischaemic stroke and transient ischaemic attack (TIA), and AF detection can be challenged by asymptomatic and paroxysmal presentation. Long-term ECG monitoring after ischaemic stroke or TIA is recommended by all major societies in cardiology and cerebrovascular medicine as a secondary prophylactic measure. However, data on stroke red

Compliance with National and International Guidelines in the Treatment of Nonmotor Symptoms in Late-Stage Parkinson's Disease

Background. National as well as international Parkinson's disease (PD) treatment guidelines are available to guide clinicians. Previous research has shown that nonmotor symptoms (NMS) are pronounced in late-stage PD and has suggested that current treatment is insufficient and could be improved. Objectives. The aim of this study was to investigate to which degree the national and international trea

Sustained Remission in Patients With Rheumatoid Arthritis Receiving Triple Therapy Compared to Biologic Therapy : A Swedish Nationwide Register Study

Objective: To compare the real-life effectiveness of biologic therapy (a biologic disease-modifying antirheumatic drug plus methotrexate [MTX]) versus triple therapy (MTX plus sulfasalazine plus hydroxychloroquine/chloroquine) for sustained remission of rheumatoid arthritis (RA). Methods: RA patients who were registered in the nationwide Swedish Rheumatology Quality Register between 2000 and 2012

Fatigue During Cancer-Related Radiotherapy and Associations with Activities, Work Ability and Quality of Life : Paying Attention to Subgroups more Likely to Experience Fatigue

Background: Having knowledge of which patients are more likely to experience fatigue during radiotherapy and the relationship between fatigue and health-related quality of life (HRQL) is important to improve identification and care of patients experiencing burdensome fatigue. Objective: To identify subgroups of patients, varying in situational, physiological, and psychological factors, who are mor

Increased hope following successful treatment for hepatitis C infection

Aims: To evaluate hope in hepatitis C patients 9 years after curative treatment with pegylated interferon and ribavirin. Background: Successful treatment of hepatitis C leads to improved quality of life in responders compared with non-responders. The long-term effect of successful treatment on hope in these patients is not known. Design: Cross-sectional follow-up study of patients who displayed a

Students’ and Teachers’ Experience of Globalization/Internationalization ‘of’ Higher Education - Emphasizing a pedagogical stance in an internationalized teaching and learning context

The conclusions in this paper are drawn from the results of four empirical studies. It has been important to take an empirical approach in the investigation, concerned with internationalization of higher education, since even though plentiful of studies over the last decades have been concerned with internationalization in/of higher education, it has not been from the perspectives from the teacher

Life satisfaction in patients with and without spinal cord Ischaemia after advanced endovascular therapy for extensive aortic disease at mid-Term follow-up

Objective: Advanced endovascular aortic repair can be used to treat patients with extensive and complex aortic disease who are at risk of spinal cord ischaemia. The aim of this study was to compare whether life satisfaction differs between patients with and without spinal cord ischaemia at mid-Term follow-up. Design: Nested case-control study. Patients: Among patients undergoing advanced endovascu

Will this hemodynamically unstable patient respond to a bolus of intravenous fluids?

IMPORTANCE Fluid overload occurring as a consequence of overly aggressive fluid resuscitation may adversely affect outcome in hemodynamically unstable critically ill patients. Therefore, following the initial fluid resuscitation, it is important to identify which patients will benefit from further fluid administration. OBJECTIVE To identify predictors of fluid responsiveness in hemodynamically uns

Rates of Progression in Patients with Alzheimer’s Disease Depending on Apolipoprotein E Genotype and Concomitant Medications.

Background: The apolipoprotein E (APOE) ε4 allele is associated with higher cholesterol levels, and an increased risk of developing Alzheimer’s disease (AD) and amyloid-related imaging abnormalities after initiation of amyloid-modifying therapies. A worse cognitive response to cholinesterase inhibitor (ChEI) treatment and longitudinal outcome in APOE ε4-carriers has been observed. Based on these c

Expiratory and inspiratory resistance and reactance from respiratory oscillometry defining expiratory flow limitation in obstructive lung diseases

Background: Expiratory flow limitation (EFL) during tidal breathing and lung hyperinflation have been identified as major decisive factors for disease status, prognosis and response to therapy in obstructive lung diseases. Aim: To investigate the delta values between expiratory and inspiratory resistance and reactance, measured using respiratory oscillometry and its correlation with air trapping a

Roadside PM2.5 concentrations measured with low-cost sensors and student science in Arba Minch, Ethiopia

Exposure to PM2.5 poses one of the biggest health threats, with traffic and biomass burning as dominant sources in urban areas of low-income countries. In Ethiopia, the combination of these two sources suggests a high roadside exposure. Because of a lack of resources for data collection, only few studies were conducted on roadside exposure in Ethiopia. Using low-cost sensors and student science co

A longitudinal 2-year follow-up of quality of life in women referred for colposcopy after an abnormal cervical smear.

OBJECTIVE: To evaluate the long-term impact on quality of life (QoL) in women referred for colposcopy after an abnormal cervical smear. STUDY DESIGN: One hundred consecutive women referred for colposcopy for the first time subsequent to receiving notification of an abnormal cervical smear. Women in the study group completed the Swedish Health Survey Short Form-36 (SF-36), the State/Trait Anxiety I

Pain and health status in adults with myelomeningocele living in Sweden

PURPOSE: To increase knowledge about pain and general health in adults with myelomeningocele, a health condition with several risk factors for pain such as musculoskeletal deformities, shunt dysfunctions, bowel problems, and urinary tract infections/stones. METHODS: Descriptive correlational pilot study (N= 51, 53% males). Chi-square tests were used to test associations among presence, impact, sev

The patient with bladder cancer. From symptoms, through treatment, with special reference to psychosocial consequences of radical cystectomy

Popular Abstract in Swedish Under de senaste 20 åren har större hänsyn tagits till den enskilde patientens önskningar och behov innan en behandling har påbörjats. Detta har skett parallellt med en snabb teknisk och medicinsk utveckling. Samtidigt som nya behandlingsmetoder tagits fram, har det också blivit angeläget att utvärdera effekten av dessa, vilket även inkluderar hur den enskilde individenFactors determining patient`s and doctor`s delay in diagnosis of bladder cancer were type of initial symptoms, level of health service first consulted and number of steps in the referral system. No correlation was found between psychosocial factors and patient`s delay. In retrospective studies after cystectomy for bladder cancer, patients with continent cutaneous diversion of urine had fewer stoma

Intracavitary Electron FLASH Radiotherapy in a Canine Cancer Patient With Oral Malignant Melanoma

PURPOSE/OBJECTIVE(S): Studies of electron FLASH radiotherapy (FLASH-RT) in companion animals are being conducted at several institutions. High energy electron beams are generally suitable for treatment of superficial cancers, but of limited use for deep-seated tumors. In this case report, the feasibility of intracavitary electron FLASH-RT is demonstrated.MATERIALS/METHODS: A canine cancer patient