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In the present study, we have investigated whether changes in vascular reactivity in congestive heart failure (CHF) patients can be detected in the cutaneous microvessels and whether these changes are due to endothelial dysfunction, are affected by increasing age and related to an ongoing inflammation. The responses to local warming and iontophoretically administered endothelium-dependent and -ind
OBJECTIVE: To evaluate the activity of benzydamine, lidocaine, and bupivacaine, three drugs with local anesthetic activity, against Candida albicans and non-albicans strains and to clarify their mechanism of activity. METHODS: The minimal inhibitory concentration (MIC) was determined for 20 Candida strains (18 clinical isolates and two American Type Culture Collection strains). The fungistatic act
We study the role of strong particle/particle interactions and stochastic fluctuations emanating from the micro-/sub-grid scale, in the context of a simple prototype hybrid system con- sisting of a scalar linear ordinary differential equation (ODE), coupled to a microscopic spin flip Ising lattice system. Due to the presence of strong interactions in the lattice model, the mean-field approximation
The present study focuses on the role of the insulin-like growth factor (IGF) system in the development of smooth muscle hypertrophy. Hypertrophy was initiated by partial ligation of portal vein or urethra in female Sprague-Dawley rats weighing approximately 220 g. Levels of mRNA were analyzed by solution hybridization. Seven days after ligation, the wet weight of the portal vein was increased abo
The optimisation of image quality vs. radiation dose is an important task in medical imaging. To obtain maximum validity of the optimisation, it must be based on clinical images. Images at different dose levels can then either be obtained by collecting patient images at the different dose levels sought to investigate-including additional exposures and permission from an ethical committee-or by man
Through alterations primarily in the penicillin-binding proteins, a non-beta-lactamase-mediated resistance to beta-lactams has evolved in Haemophilus influenzae. The virulence of these chromosomally changed strains has been questioned. To ascertain whether these alterations involve a reduction in virulence of H. influenzae and whether they could be advantageous for the bacterium during amoxicillin
Background: Central line insertion is a routine procedure in medical practice. Dislodgement of lines into the vascular system is a rare complication. We noticed that paediatric health care providers (PHCP) contact the cardiac or general paediatric surgeon for extraction of dislodged lines more frequently than using the less invasive percutaneous approach. Aim: To study the referral preference of P
An optimization procedure has been established aiming to design an integrated thermal protection system (ITPS) with minimum weight. The objective of this research is to establish the procedure and ensure its effectiveness. A corrugated sandwich panel has been chosen as the optimization problem. The ITPS geometric dimensions are considered as the design variables. The objective function is the mass
Arctic sea ice represents an important component of the climate system, and the present reduction of sea ice in the Arctic is of major concern. Despite its importance, little is known about past changes in sea-ice cover and the underlying forcing mechanisms. Here, we use diatom assemblages from a marine sediment core collected from the West Greenland shelf to reconstruct changes in sea-ice cover o
The dioecious weed Silene latifolia Poiret is thought to have spread northwards through Europe from separate southern source populations and shows a pronounced east–west pattern of differentiation in seed morphology. We used crossing experiments to investigate whether patterns of interfertility in S. latifolia are consistent with a scenario of ongoing speciation (reflected by outbreeding depressio
The Sorvik granite occurs as rounded massifs in the Revsund granite in central Sweden. The rock is medium-grained with rounded quartz crystals ('drop quartz') and occasional, sometimes albiterimmed megacrysts of K-feldspar. It is a faintly peraluminous 1-type granite with some A-type affinities showing a limited chemical variation. The SiO2 content normally varies between 68 and 77 weight%. The ro
Background and purpose: The purpose of this work was a comparison of realistic IMRT plans based on the same CT-image data set and a common predefined set of dose objectives for the planning target volume and the organs at risk. This work was part of the larger European QUASIMODO IMRT verification project. Materials and methods: Eleven IMRT. plans were produced by nine different European groups, ea
We studied if bladder cancers respond to HAMLET (human alpha-lactalburnin made lethal to tumor cells) to establish if intravesical HAMLET application might be used to selectively remove cancer cells in vivo. Patients with nonmuscle invasive transitional cell carcinomas were included. Nine patients received 5 daily intravesical instillations of HAMLET (25 mg/ml) during the week before scheduled sur
To date, a variety of pharmacological treatments exists for patients suffering epilepsy, but systemically administered drugs offer only symptomatic relief and often cause unwanted side effects. Moreover, available drugs are not effective in one third of the patients. Thus, more local and more effective treatment strategies need to be developed. Gene therapy-based expression of endogenous anti-epil
The ideals of civic participation are within much of current planning theory regarded as ways of ensuring the democratic and equitable values of planning processes, as well as offering local knowledge to those in power and awarding citizens the influence of being a part of shaping the spaces around them. However, they have also been the subject of much scrutiny; critical assessments of such activi
This thesis demonstrates how neoliberal urbanism has unrolled in the context of the Danish non-profit housing sector, using the case of Copenhagen neighbourhood Tingbjerg as a case study. Arguing that this process has significantly altered the relations of power within the neighbourhood, it further investigates the mode of resistance emerging locally as a response. Danish non-profit housing has be
This paper study political mandate concentration in Swedish municipalities. Due to the current developments in Sweden, with a reduced membership in political parties as well as a system characterized by a reduced number of commissions of trust, the effects of political mandate concentration is believed to become increasingly apparent. The purpose of this paper is to study the phenomenon of politic
The history of religion shows that religion has never been a final product. Rather religion has always been influenced by and adapted to its historical and local context. Today’s society is no exception. Globalization has meant that information, ideas and communication can take place without having to take geographical considerations. This has also effected the emergence of new religions. Synteism
In the initial stage of planning, considering the solar impact of urban layout on the building can effectively avoid some irreversible design issues, improve the indoor environment, and reduce energy demand. The typical architectural models of three representative cities (Copenhagen, Berlin and Hong Kong) were selected as the analysis cases in this study. By analysing several sunlight and solar me
