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The LPJ-GUESS dynamic vegetation model uniquely combines an individual-and patch-based representation of vegetation dynamics with ecosystem biogeochemical cycling from regional to global scales. We present an updated version that includes plant and soil N dynamics, analysing the implications of accounting for C-N interactions on predictions and performance of the model. Stand structural dynamics a
Purpose - The employment of continuous ribs in a passage involves a noticeable pressure drop penalty, while other studies have shown that truncated ribs may provide a potential to reduce the pressure drop while keeping a significant heat transfer enhancement. The purpose of this paper is to perform computer-aided simulations of turbulent flow and heat transfer of a rectangular cooling passage with
As an approach to determining the aetiology of chronic lymphocytic leukaemia (CLL), we searched for a virus expressed in human CLL B-cells by combining high-throughput sequencing and digital subtraction. Pooled B-cell mRNA transcriptomes from five CLL patients and five healthy donors were sequenced with 454 Life Sciences technology. Human reads were excluded by BLAST (Basic Local Alignment Search
BACKGROUND: Human papillomavirus (HPV) DNA testing may be useful in clarifying equivocal cervical cytologic interpretations. One application might be to standardize the meaning of equivocal interpretations from laboratories in various regions. Because international differences may be particularly marked, international comparisons of emerging data will require clear translations of "equivocal" and
From 1991 to 1998 breeding birds were surveyed in two study plots (11.2 and 8.3 ha) of the town of Solothurn, Central Plateau of Switzerland. The paper presents the results and relates habitat structure elements to species diversity On individual properties. Over the whole study period, 31 species were found in each area. Thirteen species were recorded as breeders in all years in both areas. Avera
AIMS: To compare the incidence of myocardial infarction and death in non-diabetic subjects with and without insulin resistance. METHODS: Population-based prospective cohort study, in Malmö, Sweden, of 4748 non-diabetic subjects (60% women), aged 46-68 years, with no history of myocardial infarction or stroke. The prevalence of insulin resistance was established by the homeostasis model assessment
Background: Hyper- as well as hypoglycemia may be detrimental for brain energy metabolism and even a moderate increase in blood glucose concentration can affect outcome adversely. During physiological conditions, glucose concentration obtained from microdialysis of subcutaneous adipose tissue adequately reflects plasma glucose concentration. This study examines whether this correlation is also obt
Popular Abstract in Swedish Cystatiner är endogena proteasinhibitorer som reglerar den proteolytiska aktiviteten hos papainlika cysteinproteaser, så som humant cathepsin B, H, K, L och S. Cystatin C, som finns i de flesta humana vävnader och vävnadsvätskor, är den starkaste hämmaren av lysosomala cysteinproteaser. Förändring i balansen mellan cysteinproteaser och cystatiner har vid flera olika canCystatins are endogenous protease inhibitors that regulate the proteolytic activities of family C1 (papain-like) cysteine proteases, such as human cathepsins B, H, K, L, and S. Cystatin C shows the fastest inhibition and the highest affinity of all cystatins towards lysosomal cysteine proteases in general and is widespread in human tissues and body fluids. Alterations in the balance between the cy
Do altered land management practices offer possibilities to sequester carbon in the soil and thereby mitigate increasing atmospheric CO2 as well as improve local soil fertility? This study investigates the impact of fallow periods on soil organic carbon in semiarid subsistence agroecosystems on sandy and poor soils in Kordofan, Sudan. The area is characterized by low-input cultivation of millet an
Popular Abstract in Swedish Ur ett evolutionärt perspektiv har förmågan att lagra energi varit fördelaktig när tillgången på föda varit begränsad. I våra dagar i västvärlden råder det ingen brist på mat och vår förmåga att lagra energi har istället blivit en börda i dubbel bemärkelse. Energi lagras i kroppen framförallt i form av fett, s.k. triglycerider. Övervikt och fetma kan idag sägas utgöra eHormone-sensitive lipase (HSL) has a wide tissue distribution with the highest expression found in white adipose tissue (WAT). HSL also has a unique ability to hydrolyze a large panel of substrates including acylglycerols, cholesteryl esters and retinyl esters. HSL is potentially a new drug target for the treatment of obesity and type II diabetes. However, as HSL is not only expressed in adipose t
Aims: This study examined whether middle-aged men exhibiting markers of early ageing showed a different pattern of social factors, lifestyle, and biological variables compared with controls, and whether early ageing was associated with an increased mortality risk. Subjects and methods: We used a subgroup of 5,722 middle-aged men (mean age 47 years), investigated twice, from the Malmö Preventive Pr
BACKGROUND: Angiotensin II (Ang II) has been implicated in the development of cardiac fibrosis. The aims of the present study were to examine expression and activity of ACE and of angiotensin receptors in human cardiac fibroblasts cultured from dilated cardiomyopathic and ischemic hearts. The effects of Ang II on fibroblasts were also investigated. METHODS AND RESULTS: Human cardiac fibroblasts we
Periodontitis is an inflammatory disease of the supporting structures of the teeth caused by, among other pathogens, Prevotella intermedia. Many strains of P. intermedia are resistant to killing by the human complement system, which is present at up to 70% of serum concentration in gingival crevicular fluid. Incubation of human serum with recombinant cysteine protease of P. intermedia (interpain A
BACKGROUND: The existence of a link between inflammation in upper and lower airways is well established. It may therefore be assumed that the nose could be used to study inflammatory events in the lower airways. OBJECTIVE: This study aimed to evaluate a lipopolysaccharide (LPS) nasal challenge model by investigating the effect of the CXCR2 inhibitor AZD8309 on neutrophilic inflammation. METHODS: A
Objective To investigate the reproductive and oncologic outcome following robotic radical trachelectomy for early stage cervical cancer. Methods All women with early stage cervical cancer planned for fertility-sparing robotic trachelectomy between December 2007 and April 2015 at two tertiary referral centers in Sweden were identified. Perioperative- and follow-up data was retrieved from prospectiv
The purpose of this study was to characterize the outcome of attempted endovascular intervention in patients with acute embolic or thrombotic superior mesenteric artery (SMA) occlusion. The records of 21 patients during a 3-year period between 2005 and 2008 were retrieved from the in-hospital registry. The first group included 10 patients (6 women and 4 men; median age 78 years) with acute embolic
Mechanically strong and flexible membranes with very high local concentrations of immobilized proton-conducting phosphonic acid have been achieved by grafting poly(vinylphosphonic acid) side chains onto polysulfones. The graft copolymers were prepared by anionic polymerization of diethyl vinylphosphonate initiated from lithiated polysulfones, followed by quantitative cleavage of the ester function
Objective. To investigate the risk of cardiovascular disease (CVD) in patients with rheumatoid arthritis (RA) treated with tumor necrosis factor (TNF) inhibitors, compared to a standard RA population. Methods. Patients were recruited from a regional register, which includes over 90% of patients with RA started on TNF blockers in 1999 or later, and a local community based cohort of RA patients, est
Bacterial endotoxin has been suggested as responsible for the development of subjective symptoms and transient or chronic lung function impairment seen after exposure to organic dusts in cotton mills, poultry houses, swine confinement buildings and saw mills. Animal experiments have demonstrated bronchoalveolar neutrophilia being the most prominent cell response in animals following bacterial lipo
Detailed ecological, morphological and molecular analyses were performed in mixed populations of diploid and autotetraploid Dactylorhiza maculata s.l. in Scandinavia. Comparisons were made with pure populations of either diploid ssp. fuchsii or tetraploid ssp. maculata. It was shown that mixed populations are the result of secondary contact between ssp. fuchsii and ssp. maculata. No patterns of re
