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Overwash is the flow of water and sediment over the crest of a beach system when the runup level of waves or the water level, often enhanced by storm surge, exceeds the local beach or dune crest height. The impacts of overwash on coastal barriers or low lying mainland coasts are striking. Overwash may cause deposition of sand on and landward of the beach crest, large fan shaped deposits on back ba
The dimeric metabolic enzyme phosphoglucose isomerase (PGI, EC 5.3.1.9) plays an essential role in energy production. In the grass Festuca ovina, field surveys of enzyme variation suggest that genetic variation at cytosolic PGI (PGIC) may be adaptively important. In the present study, we investigated the molecular basis of the potential adaptive significance of PGIC in F. ovina by analyzing cDNA s
In animal models of Parkinson's disease, striatal overactivation of ERK1/2 via dopamine (DA) D1 receptors is the hallmark of a supersensitive molecular response associated with dyskinetic behaviors. Here we investigate the pathways involved in D1 receptor-dependent ERK1/2 activation using acute striatal slices from rodents with unilateral 6-hydroxydopamine (6-OHDA) lesions. Application of the dopa
Popular Abstract in Swedish Dödligheten i skador i Sverige har under de senaste årtiondena minskat, en minskning som idag dock har planat ut. Antalet dödade i transportolyckor och i arbetsplatsolyckor i Sverige har minskat under de senaste 40 åren vilket kan ses som ett resultat av ett effektivt säkerhetsarbete. När det gäller fallolyckor så har däremot andelen som dör av sina skador ökat markant Injuries are often associated with long-term suffering and lowered functioning, and personal injuries impose a huge burden on medical care and health services in addition to the costs associated with impaired functional ability. Each year in Sweden, falling accidents are experienced by a third of those aged 60 or over and half of those aged 80 or over, while injuries from traffic accidents still a
Background and aims: Acute pancreatitis (AP) is a common condition characterized by premature protease activation, abdominal pain and leakage of pancreatic enzymes to the circulation. Approximately 10% develop systemic inflammation and persistent organ failure. Although persistent organ failure in AP is associated with considerable mortality, no therapies to moderate the disease are at hand. This
OBJECTIVE: Systemic effects of carbon dioxide (CO(2)) insufflation during left-sided cardiac surgery were evaluated in a prospective randomized study, with regard to acid-base status, gas exchange, cerebral hemodynamics, and red blood cell morphology. METHODS: Twenty patients undergoing elective left-sided cardiac surgery were randomized to de-airing procedure either by CO(2) insufflation techniqu
The present study employs square cross-section ribbed channels with different arrangements of downstream half-size ribs to determine the most optimal configurations for augmenting heat transfer rates with minimized pressure drop penalties. The channel inlet Reynolds number ranges from 20,000 to 160,000. The influence of downstream ribs arrangement on the overall performance characteristics of ribb
Background The well-being of patients with Parkinson's disease may be improved by pharmaceutical care in community pharmacies. Objective To investigate the effects of standardised pharmaceutical care on health outcomes and quality of drug treatment in patients with Parkinson's disease. Setting Community pharmacies in Germany. Method An open-label, multicentre, longitudinal, parallel-group study wa
Pollinator populations have suffered severe declines in many industrialised countries due to reduced floral and nesting resources, brought on by agricultural intensification. One potential method of mitigating these effects is creating flower strips. Most previous studies have shown higher pollinator abundances in flower strips, but none have been able to demonstrate increased pollinator abundance
The connection between rune stones and churches is a known phenomenon. Unfortunately, very little is known about the previous function of the church sites, and consequently very little is known about what the connection between rune stones and churches means. The purpose of this study is to examine the rune stones connected to churches in the administrative province of Jönköping, in an effort to a
In the modern business environment, there is growing number of companies placing weight on sustainability-related issues, such as waste management, local communities, use of resources etc. At the same time such stakeholders as investors, consumers, employees and communities are increasingly interested in understanding company’s efforts and progresses in the area of sustainability. With that respec
The function of proteins is influenced not only by the atomic structure but also by the detailed structure of the solvent surrounding it. Computational studies of protein structure also critically depend on the water structure around the protein. Herein we compare the water structure obtained from molecular dynamics (MD) simulations of galectin-3 in complex with two ligands to crystallographic wat
Popular Abstract in Swedish Många grundläggande processer i naturen involverar transport av energi från ett ställe till ett annat. Ett exempel på detta är fotosyntesen där solljus fångas upp av molekylkomplex, för att sedan transporteras till ett reaktionscenter. I reaktionscentret byggs den laddning upp som sedan används för att framställa växtmassa. För att minimera energiförlusten i den här typAn efficient transfer of energy in molecular systems has proven to be of fundamental importance both in nature and industrial applications. The ability of molecules to work together forming collective excitations, so-called excitons, plays a key role in for example the extraordinary fast energy transfer involved in the first steps of photosynthesis. The characterization of excitonic states in conj
BACKGROUND: Neutrophil extracellular traps (NETs) are known to play an important role in the pathophysiology of acute pancreatitis (AP). Activation of the complement cascade has been shown to occur in AP. The aim of this study was to examine whether complement component 3 is involved in the generation of NETs in AP.METHODS: AP was induced in wild-type and C3-deficient mice by retrograde infusion o
The increase of the consumer electronics market the last couple of decades has been one of the main drivers of IC process technology development. The majority of the ICs are used in digital applications, and for these CMOS is the choice of technology. The urge to squeeze more transistors on to a given area has led to shrinking feature sizes. It has resulted in higher transition frequencies and red
Objectives To assess 2-year durability of joint contracture correction following collagenase injections for Dupuytren's disease. Design Prospective cohort study. Setting Orthopaedic Department in Sweden. Participants Patients with palpable Dupuytren's cord and active extension deficit (AED) ≥30° in the metacarpophalangeal (MCP) and/or proximal interphalangeal (PIP) joint. A surgeon injected 0.80 m
BACKGROUND: Continuous epidural infusions of local anaesthetics have become increasingly popular in postoperative pain treatment, especially as they permit early mobilisation. Ropivacaine is a promising new agent which induces more pronounced sensory than motor blockade. This study was focused on the influence of continuous epidural infusion of ropivacaine on impulse conduction in large nerves (by
Field observations of new particle formation and the subsequent particle growth are typically only possible at a fixed measurement location, and hence do not follow the temporal evolution of an air parcel in a Lagrangian sense. Standard analysis for determining formation and growth rates requires that the time-dependent formation rate and growth rate of the particles are spatially invariant; air p
The employer has always played a dominant role in the Swedish labor market, developments during 1900-century, however, sought to restrict the employer's management rights under the law and agreements. 1997 came § 25a LAS, preferential rights for part-time employees to higher levels of employment. Lunning believe that legislative and preparatory work to § 25a LAS do not give answers to all appl
In Sweden 16 national goals have been elaborated to aim for an environmentally sustainable society. These goals should not only be implemented at a national level but also at the regional and community level. In Lund 13 documents have been developed, for 13 of the 16 national goals describing the environmental state in Lund associated to the goal in question. These documents will lead to local env
