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Objective. To investigate the contrasting roles of plasminogen deficiency between models of collagen-induced arthritis (CIA) and antigen-induced arthritis (AIA). Methods. We developed a new animal model of arthritis, which we have called local injection-induced arthritis (LIA). In this model, we replaced methylated bovine serum albumin, which is normally used as an immunogen and is injected intraa

We reviewed results of SBRT treatment of 138 patients with medically inoperable stage I NSCLC treated during 1996 - 2003 at five different centres in Sweden and Denmark. Mean age was 74 years ( range 56 - 90) with 69 men and 72 women. SBRT was delivered using a 3D conformal multifield technique and a stereotactic body frame. Doses delivered were 30 - 48 Gy (65% isodose at the periphery of planning

One of the most well-known facts about unit root testing in time series is that the Dickey--Fuller (DF) test based on OLS demeaned data suffers from low power, and that the use of GLS demeaning can lead to substantial power gains. Of course, this development has not gone unnoticed in the panel unit root literature. However, while the potential of using GLS demeaning is widely recognized, oddly eno

Objective. The aim of this study was to present the outcome of patients treated with salvage cryotherapy after radiotherapy for prostate cancer at one institution. Materials and methods. Consecutive patients treated between 2007 and 2013 with transperineal cryotherapy for biopsy-verified local recurrence after radiotherapy were investigated. An external reviewer retrieved outcome data retrospectiv

We have a limited amount of greenhouse gases left to emit, our global carbon budget, if we are to divert the worst effects of the climate crisis. This study aimed to map how municipalities implement carbon-budgeting in their efforts to fulfil the Paris agreement, and investigate why the instrument is not more frequently used. A survey among Swedish municipalities was carried out, in two stages. A

The aim of this study was to analyze if soya framing would be nationally-economical to produce with a vertical hydroponic system, compared to being imported from Brazil. With the intention to study the production cost and climate impact effects of local production. The costs and benefits of the culture have been analyzed and compared to imported soya from Brazil. In order to answer the questions o

In 1947 the municipalities in Sweden received the monopoly to decide on and plan their land. Despite this, over 80 percent of the municipalities in Sweden say they experience lack of housing today. This thesis applies The Homevoter Hypothesis introduced by William A. Fischel in 2001 to try to explain why some municipalities are not able to construct enough housing for their inhabitants. The hypoth

Decentralization has in recent decades become a common concept in public policy making especially in developing countries. The concept, defined here as the transfer of functions, responsibilities and financial resources to lower levels of government, is further expected to have a positive effect on a country´s development process by reducing the inefficiency associated with a centralized form of g

Enligt ett flertal forskare uppstår det en konflikt då västerländska turister besöker muslimska destinationer. När individer med olika sedvänjor, värderingar och världsbilder möts kan det uppstå en konflikt i och med att individer önskar använda platsen på olika sätt. En del destinationer har valt att, med hjälp av en fysisk uppdelning och/eller en “double-standard policy”, upprätta gränsdragningaAccording to a large amount of researchers, conflict arises as western tourists visit Muslim destinations. When differentiating customs, values and worldviews meet, a conflict can arise in relation to the utilisation of the physical area in which the two cultures interact. With the help of physical separation and double standard policies, some destinations have chosen demarcation as a tool to upho

The Colombian peace agreement, which has brought an end to a prolonged internal armed conflict has led to significant land use changes that underscore existing inequalities and struggles over natural resources. The expansion of industries such as cattle ranching, agriculture, and extraction is encroaching on indigenous territories and protected areas, resulting in negative consequences for communi

Rapid urbanization can change local climate by increasing land surface temperature (LST), particularly in metropolitan regions. This study uses two decades of remote sensing data to investigate how urbanization-induced changes in land use/land cover (LULC) affect LST in the Beijing Region, China. By focusing on the key issue of LST and its contributing variables through buffer zones, we determined

Design of inhalable mRNA therapeutics is promising because local administration in the respiratory tract is minimally invasive and induces a local response. However, several challenges related to administration via inhalation and respiratory tract barriers have so far prevented the progress of inhaled mRNA therapeutics. Here, we investigated factors of importance for lipid nanoparticle (LNP)-media

In the last few years there has been an ongoing debate concerning the methods of assessing the quality of public libraries and their services. This study investigates the opinions and needs of the users at four different public libraries in Malm : the local libraries in Bellevueg rden, Limhamn, and Kirseberg, and the main library in central Malm . The purpose was to find out whether different user

Background: Neuropeptides, such as substance P (SP), have long been seen as mediators of widespread continuous airway inflammation, a process known as neurogenic inflammation. However, this has been difficult to demonstrate clinically, suggesting an alternative role for these signaling molecules. Objectives: We sought to examine the role of SP in nasal infection by assessing the release of SP in r

Correct reproductive timing is crucial for fitness. Breeding phenology even in similar species can differ due to different selective pressures on the timing of reproduction. These selection pressures define species' responses to warming springs. The temporal match-mismatch hypothesis suggests that timing of breeding in animals is selected to match with food availability (synchrony). Alternatively,

BACKGROUND: The primary objective was to investigate the clinical and radiological outcome in patients undergoing major hip surgery using a novel antibiotic containing bone substitute for local augmentation in trochanteric fracture fixation or revision of total hip arthroplasty (THA).METHODS: We implanted a novel biphasic bone substitute CERAMENT™|G consisting of hydroxyapatite, calcium sulphate a

This paper discusses static stability of a planar object grasped by multifingers with three joints. Each individual joint (prismatic joint or revolute joint) is modeled as a linear spring stiffness. The object mass and the link masses are also included. We consider not only pure rolling contact but also frictionless sliding contact. The grasp stability is investigated using the potential energy me

This paper investigates the effect of the presence of a rib on the end-wall heat transfer of an obstacle by liquid crystal thermography. An obstacle with a rectangular cross section is placed in a rectangular channel and blocks the entire height of it (AR = 4). A rib with a square cross section is placed at two positions, i.e., in the upstream and downstream areas of the obstacle, respectively. An