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Developing a rapid flow cytometry method to determine ultraviolett light-emitting-diode (UV-LED) -mediated killing of bacteria in drinking water.

A next-generation drinking water purification device has been developed which uses UV-LEDs to create high intensity UV light to inactive the bacteria present in the water that flows through the device tube chamber. The capacity of the different setups of the devices to perform water purification was examined by experimental testing. This report investigates using a new flow cytometry approach comp

Observations on de Bruijn graphs

Abstract of chapter 1 For n >= 2 the number of mixing n-step subshifts of finite type (sft) over the alphabet {0, 1} is proven to be at least 15/16 times the number of transitive n-step sfts. A conjecture assumes the latter to be at least 2^(3*2^(n-1)-n). Abstract of chapter 2 The alternating colouring function is defined. Strings over the alphabet {0, 1} are divided in colourable and non-colouraImagine an of characters A and B. Such can be thought of as a paper strip with As and Bs written on it, one end of which one holds in the hand while the other stretches over the horizon without ever ending. Or as a calculator that displays a new character each second. Or as a printer with an infinite amount of paper and ink that unfortunately only prints As and Bs. In contrast to infinite strings

The Path Dependence of European Copyright.

This article analyses the path dependence of European copyright. It shows how copyright is legally constructed, is harmonised through international treaties and European regulatory efforts in terms of InfoSoc Directive and the IPRED, and is also affected by the Data Retention Directive and the Telecommunications Reform package. Furthermore, the “secretly” negotiated ACTA agreement is discussed as

Reappraisal of the intravenous glucose tolerance index for a simple assessment of insulin sensitivity in mice

Pacini G, Ahren M, Ahren B. Reappraisal of the intravenous glucose tolerance index for a simple assessment of insulin sensitivity in mice. Am J Physiol Regul Integr Comp Physiol 296: R1316-R1324, 2009. First published February 11, 2009; doi: 10.1152/ajpregu.90575.2008.- Mice are increasingly used in studies where measuring insulin sensitivity (IS) is a common procedure. The glucose clamp is labor

Discharge and sediment transport in the Kapuas river

Deteriorating water quality is a challenge which affects people of the entire world, with a growing population and increased industrialization worldwide. The problem is especially apparent in many developing nations where water resource management must be improved to secure a future sustainable supply. This study was undertaken as a bachelor degree within the MFS-program funded by SIDA. The study

Female exposure to phthalates and time to pregnancy : A first pregnancy planner study

STUDY QUESTION Is female exposure to phthalate metabolites associated with reduced fecundity, as estimated by prolonged time to pregnancy (TTP)? SUMMARY ANSWER Female exposure to monoethyl phthalate (MEP) but not monobutyl phthalate (MBP), monobenzyl phthalate (MBzP) and monoethylhexyl phthalate (MEHP) was associated with a longer TTP. WHAT IS KNOWN ALREADY Male exposure to phthalates is potential

Multivoxel 1H-MR Spectroscopy Biometrics for Preoprerative Differentiation Between Brain Tumors

We investigated multivoxel proton magnetic resonance spectroscopy (1H-MRS) biometrics for preoperative differentiation and prognosis of patients with brain metastases (MET), low-grade glioma (LGG) and high-grade glioma (HGG). In total, 33 patients (HGG, 14; LGG, 9; and 10 MET) were included. 1H-MRS imaging (MRSI) data were assessed and neurochemical profiles for metabolites N-acetyl aspartate (NAA

Effects of calcium and substrate on force-velocity relation and energy turnover in skinned smooth muscle of the guinea-pig

Mechanical properties and rate of ATP breakdown (JATP) have been determined in the chemically skinned guinea-pig taenia coli at 22 degrees C. The influence of varied [Ca2+], [Mg ATP] and muscle length were investigated. The shortening response after a step decrease in force (isotonic quick release) was highly curvilinear in the first 100-200 ms. This effect was shown to be a time-dependent respons

IGFBP1 and IGFBP3 polymorphisms predict circulating IGFBP-3 levels among women from high-risk breast cancer families.

The insulin-like growth factor (IGF) pathway has been implicated as risk modifier in premenopausal breast cancer. In this study, associations between single nucleotide polymorphisms (SNPs) and diplotypes in the IGFBP1 and IGFBP3 genes and circulating IGFBP-3 levels, BRCA family status and breast cancer among women from high-risk breast cancer families were investigated. Nine IGFBP1 and IGFBP3 SNPs

Discrete Stochastic Time-Frequency Analysis and Cepstrum Estimation

Popular Abstract in Swedish Det är ofta fördelaktigt att i olika sammanhang representera våra observationer av verkligheten med en följd av tal. Så skilda exempel som ljud, bilder, hjärnvågor, havsvattenvågor, jordbävningar och aktiekurser kan låta sig beskrivas av följder av tal. Man kan med fördel föreställa sig följden som en uppritad graf, där den horisontella axeln beskriver tidpunkten för mäThe theory of stochastic time-frequency analysis of non-stationary random processes has mostly been developed for processes in continuous time. In practice however, random processes are observed, processed, and interpreted at a finite set of time points. For processes in continuous time, the ambiguity domain has interesting properties which makes it particularly useful. One such property is that t

An international study to increase concordance in Ki67 scoring.

Although an important biomarker in breast cancer, Ki67 lacks scoring standardization, which has limited its clinical use. Our previous study found variability when laboratories used their own scoring methods on centrally stained tissue microarray slides. In this current study, 16 laboratories from eight countries calibrated to a specific Ki67 scoring method and then scored 50 centrally MIB-1 stain

Endogenous androgens and risk of epithelial invasive ovarian cancer by tumor characteristics in the European Prospective Investigation into Cancer and Nutrition

The role of endogenous androgens and sex hormone-binding globulin (SHBG) in ovarian carcinogenesis is poorly understood. Epithelial invasive ovarian cancer (EOC) is a heterogeneous disease and there are no prospective data on endogenous androgens and EOC risk by tumor characteristics (histology, grade, stage) or the dualistic model of ovarian carcinogenesis (i.e. type I vs. type II, leading to les

YAP1 is an independent prognostic marker in pancreatic cancer and associated with extracellular matrix remodeling

BACKGROUND: Pancreatic cancer is a major cause of cancer-related mortality. The identification of effective biomarkers is essential in order to improve management of the disease. Yes-associated protein 1 (YAP1) is a downstream effector of the Hippo pathway, a signal transduction system implicated in tissue repair and regeneration, as well as tumorigenesis. Here we evaluate the biomarker potential

Non-linear transformations of age at diagnosis, tumor size, and number of positive lymph nodes in prediction of clinical outcome in breast cancer

Background: Prognostic factors in breast cancer are often measured on a continuous scale, but categorized for clinical decision-making. The primary aim of this study was to evaluate if accounting for continuous non-linear effects of the three factors age at diagnosis, tumor size, and number of positive lymph nodes improves prognostication. These factors will most likely be included in the manageme

SENSory re-learning of the UPPer limb after stroke (SENSUPP) : Study protocol for a pilot randomized controlled trial

Background: Many stroke survivors suffer from sensory impairments of their affected upper limb (UL). Although such impairments can affect the ability to use the UL in everyday activities, very little attention is paid to sensory impairments in stroke rehabilitation. The purpose of this trial is to investigate if sensory re-learning in combination with task-specific training may prove to be more ef

A model for the temperature and density dependent reemergence of the bark beetle Ips typographus

A model is presented that describes the reemergence of parent spruce bark beetles, Ips typographus, based on breeding density and temperature conditions. Laboratory data obtained at one constant temperature provide the distribution of reemergence time and different combinations of threshold temperatures and degreedays (°D) at mean reemergence. Of these combinations, 167.71 °D above 7.5 °C gave the

DFA as a window into postural dynamics supporting task performance : Does choice of step size matter?

Introduction: Detrended Fluctuation Analysis (DFA) has been used to investigate self-similarity in center of pressure (CoP) time series. For fractional gaussian noise (fGn) signals, the analysis returns a scaling exponent, DFA-α, whose value characterizes the temporal correlations as persistent, random, or anti- persistent. In the study of postural control, DFA has revealed two time scaling region