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BACKGROUND: Owing to the large variation in treatment response among patients with high-risk prostate cancer, it would be of value to use objective tools to monitor the status of bone metastases during clinical trials. Automated Bone Scan Index (aBSI) based on artificial intelligence has been proposed as an imaging biomarker for the quantification of skeletal metastases from bone scintigraphy.OBJE

Aims/hypothesis: Low birthweight is a risk factor for type 2 diabetes but it is unknown whether low birthweight is associated with distinct clinical characteristics at disease onset. We examined whether a lower or higher birthweight in type 2 diabetes is associated with clinically relevant characteristics at disease onset. Methods: Midwife records were traced for 6866 individuals with type 2 diabe

BACKGROUND: Among asymptomatic patients with severe carotid artery stenosis but no recent stroke or transient cerebral ischaemia, either carotid artery stenting (CAS) or carotid endarterectomy (CEA) can restore patency and reduce long-term stroke risks. However, from recent national registry data, each option causes about 1% procedural risk of disabling stroke or death. Comparison of their long-te

The aim of this study is to characterize emulsion systems by self-diffusion PGSE NMR methods. The specifics of the emulsions studied are all taken from the literature and they are of the W/O or O/W type stabilized with different emulsifiers. We have investigated what characteristics of emulsions that the NMR self-diffusion technique can shed light on. The diffusion behavior of the liquid inside th

Background: The understanding of inhaled particle respiratory tract deposition is a key link to understand the health effects of particles or the efficiency for medical drug delivery via the lung. However, there are few experimental data on particle respiratory tract deposition, and the existing data deviates considerably when comparing results for particles > 1 μm. Methods: We designed an experim

BackgroundLoss to follow-up (LTFU) from tuberculosis (TB) treatment and care is a major public health problem as patients can be infectious and also may develop a multi-drug resistant TB (MDR-TB). The study aimed to assess whether LTFU differs by the distance TB patients travelled to receive care from the nearest health facility.MethodsA total of 402 patient cards of TB patients who received care

Polycyclic aromatic hydrocarbons (PAHs) have endocrine disrupting properties and they cross the placental barrier, but studies on gestational exposure and child anthropometry are inconclusive. We aimed to elucidate the impact of early gestational PAH exposure on anthropometry from birth to 10 years of age in 1295 mother-child pairs from a nested sub-cohort of the MINIMat trial in Bangladesh. Sever

Background: Repolarization prolongation can be the earliest electrophysiological change in ischemia, but its role in arrhythmogenesis is unclear. The aim of the present study was to evaluate the early ischemic action potential duration (APD) prolongation concerning its causes, expression in ECG and association with early ischemic ventricular fibrillation (phase 1A VF). Methods: Coronary occlusion

Citizens are not born, they are made. Based on fieldwork in two upper-secondary school classes in Sweden – an Introductory Programme class and a Social Science Programme class – this dissertation focuses on how pupils form their identities as citizens in a democratic society. Citizens are made in interaction with the society they inhabit, an interaction where power is always present. Although Swed

The infrastructure and the traffic that it brings affect wild animals and thus the entire biodiversity. The human built up network of cities and connecting roads are major barriers for many species in the natural world, making it harder for them to move through the landscape. The more roads in a landscape, the more fragmented it gets and with it important habitats get degraded. Long-term effects f

Gamification is a new trend that seeks to engage people and change their behaviour by implementing game-design thinking in non-game contexts. Recent analytics predicts that more than 70 % of the world’s 2000 largest organisations will have at least one gamified platform by 2014, which indicates that gamification is, and will continue to be, very important in the future of IT-strategy and digital m

The economie models of business are eonstantly developing and today il seems as if parts of the service industry are evolving inta a so called experienee economy. Collexium exclusive driver' s club has the intention of delivering experienees to a segment of automobil e enthusiasts in South Florida. As the company started out as late as December 2006, there are parts of the original strategy th

Animals´ omnipresence in human society makes them both close to and yet remarkably distant from humans. Human and animal lives have always been entangled, but the way we see and practice the relationships between humans and animals – as close, intertwined, or clearly separate – varies from time to time and between cultures, societies, and even situations. By putting these complex relationships in

https://www.pi.lu.se/sites/pi.lu.se/files/exploring_the_animal_turn_hela.pdf - 2026-06-12

Motivation: Proteomics is the large-scale study of all the proteins found in a cell, tissue or organism. In the last few years, and thanks to the development of mass spectrometry and bioinformatics, proteomics has led the research in several fields, ranging from medicine to agriculture. In order to reconstruct the amino acid sequence de novo protein sequencing can be used. It uses the protein’s mo

Genom att skapa och använda ett ramverk för att undersöka avgöranden från Mark- och miljööverdomstolen har jag analyserat om partiskhet är ett relevant skäl för domstolen att inte lita på partssakkunnig i miljöprocessen. Underlag för analysen är ett stort antal rättsfall från Mark- och miljööverdomstolen där argumentation om partiskhet förekommer. Det finns anledning att skilja mellan två olika säBy creating and using a framework to examine the decisions of Mark- och miljööverdomstolen I analyzed if bias is a valid reason for the court not to trust an expert hired by a party in the environmental process. Material for the investigation is a large number of cases from Mark- och miljööverdomstolen where arguments of bias exist. There is reason to distinguish between two different ways in whic

In the Swedish contemporary media landscape, marked by limited financial resources, many local newspapers are searching for sustainable business models. This reality brings an unprecedented challenge: finding a balance between the market-driven demands of economic efficiency and audience expectations of trustworthy local news. A way of doing this is by writing captivating headlines that appeal to

Introduction: The transition from pediatric to adult healthcare represents a crucial period for adolescents and youth living with HIV. When this healthcare transition is not properly managed, it can result in negative outcomes such as loss to follow-up (LTFU), increased morbidity, and mortality. Therefore, it is essential to estimate the incidence rate and identify predictors of loss to follow-up

We present the first data release of VELOcities of CEpheids (VELOCE), dedicated to measuring the high-precision radial velocities (RVs) of Galactic classical Cepheids (henceforth, Cepheids). The first data release (VELOCE DR1) comprises 18 225 RV measurements of 258 bona fide classical Cepheids on both hemispheres collected mainly between 2010 and 2022, along with 1161 observations of 164 stars, m

Objective To date, the major pathways contributing to cardiovascular disease among night shift workers remain poorly understood. MicroRNAs (miRNAs) have been identified as novel regulators of cardiovascular risk factors and are estimated to control more than 30 candidate miRNAs among night shift workers.Materials and Methods RNA was extracted from plasma samples of 110 night and 90day shift worker

Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: results from the prospective TEDDY study 1Beyerlein A, et al. J Med Genet 2018;0:1–4. doi:10.1136/jmedgenet-2018-105532 Short report Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: results from the prospective TEDDY study Andreas Beyerlein,1 ezio Bonif

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/95%2010262018_679_95_MP165b_Beyerlein_JMedGenetics_2018.pdf - 2026-06-12