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Chronic kidney disease of non-traditional origin (CKDnt) and acute kidney injury (AKI) often affect heat-stressed Mesoamerican manual workers. Inflammation occurs concurrently with AKI in this population, but its role remains unknown. To explore links between inflammation and kidney injury in heat stress, we compared levels of inflammation-related proteins in cutters with and without increasing se
Crohn’s disease (CD) and ulcerative colitis (UC) are the two main types of inflammatory bowel disease (IBD). The prevalence of these conditions is approximately 0.7%. With the advent of new treatments and improved management algorithms throughout the last century, the mortality rates associated with these conditions have decreased steeply. However, IBD is still a major cause of lifetime morbidity.
Background: Processing the surface electromyogram (sEMG) to decode movement intent is a promising approach for natural control of upper extremity prostheses. To this end, this paper introduces and evaluates a new framework which allows for simultaneous and proportional myoelectric control over multiple degrees of freedom (DoFs) in real-time. The framework uses multitask neural networks and domain-
BACKGROUND: The clinical importance of intraprocedural stent thrombosis (IPST) during percutaneous coronary intervention in the contemporary era of potent oral P2Y12 inhibitors is not established. The aim of this study was to assess IPST and its association with clinical outcome in patients with myocardial infarction undergoing percutaneous coronary intervention with contemporary antithromboticmed
BACKGROUND: Colorectal cancer (CRC) incidence is increasing among young adults below screening age, despite the effectiveness of screening in older populations. Individuals with diabetes mellitus are at increased risk of early-onset CRC. We aimed to determine how many years earlier than the general population patients with diabetes with/without family history of CRC reach the threshold risk at whi
Local targeted treatment of bone and joint infections using antibiotic-containing carriers is a common practice today. A recently FDA approved biphasic calcium sulphate/hydroxyapatite (CaS/HA) carrier containing gentamicin has been reported to give a sustained drug release, highly effective in eradicating bone infections. We present the first study evaluating the widely used aminoglycoside tobramy
In pre-clinical imaging, tumor response to radionuclide therapy can be monitored with PET imaging. Radionuclides used for therapy such as 177Lu emit a significant amount of low energy photons. These photons may have an energy high enough to penetrate the imaged object and are the prone to be detected. Although these phtons are likely to be rejected electronically, they add dead-time to the system
Quantitative cardiovascular Magnetic Resonance Imaging techniques are gaining wide acceptance within the MR community due to their potential to diagnose non-localized disease, guide therapy and improve patient outcome. During the last decade, there has been an increasing interest for developing new techniques that allow for simultaneous quantification of both T1 and T2 maps of myocardium. Newer st
BACKGROUND: Pre-treatment with unfractionated heparin is common in ST-segment elevation myocardial infarction (STEMI) protocols, but the effect on intracoronary thrombus burden is unknown. We studied the effect of heparin pre-treatment on intracoronary thrombus burden and Thrombolysis in Myocardial Infarction (TIMI) flow prior to percutaneous coronary intervention in patients with STEMI.METHODS: T
Background: This study investigates a broad spectrum of psychiatric disorders, substance use disorders, gambling, and internet gaming disorders in Swedish 18-year-old boys and girls with the aim of estimating the prevalence of disorders and comorbidity. Methods: We used a two-phase design with screening to detect candidates for clinical interviews. Screening included 949 adolescents (55.6% girls),
This work provides new insights into the presence of 239Pu, 240Pu, 241Pu, and 236U in the Southern Hemisphere through the study of peat bog cores from marshlands in Madagascar (19°S). 210Pb, 238Pu and 239+240Pu activities were characterized by alpha spectrometry in previous studies. Here, Pu from alpha-spectrometry discs corresponding to 10 peat-bog cores (85 samples) was reassessed for the aim of
Internet har blivit ett brottsverktyg som gjort det möjligt för förövare att genomföra sexuella övergrepp mot barn. Högsta domstolen meddelade år 2015 en dom som innebar att sexuella övergrepp kan begås på distans. Domen medförde att sexualbrott inte länge skulle betraktas som egenhändiga brott och en gärningsman kunde därmed dömas till ansvar om personen förmått brottsoffret att utföra den sexuel
Videospelsbranschen växer ständigt och globalt omsätter den idag flera hundra miljarder kronor. Bakom varje enskild speltitel ligger omfattande investeringar av både tid och kapital. Upphovsrätten är den immaterialrätt som ger skydd åt videospel. Att spelutvecklarna kan erbjudas ett effektivt skydd är essentiellt för branschens fortsatta utveckling. Omfattningen av, och formerna för, det upphovsräEvery year video game sales reach beyond several billion USD globally and the video game industry is ever expanding. The production of a single game title requires substantial investments of both time and capital. Video games are protected by copyright. Effective copyright protection is essential for the industry’s continued development as it is a major economic incentive for the creation of video
Sedan Skatteverket drog igång processerna mot nyckelpersonerna bakom riskkapitalfonderna och den höga inkomst de uppbär i form av s.k. carried interest har en rättsutveckling tagit fart på det skatterättsliga området. Efter att Skatteverket inledningsvis nekats prövningstillstånd valde de en ny linje för att komma åt denna höga inkomst, närmare bestämt genom fåmansföretagsreglerna. Skatteverket mSince the Swedish Tax Agency first pursued the key people behind the venture capital funds regarding the high income they receive as dividend, in the form of so-called carried interest, has a legislative development gained momentum in the Swedish tax law area. After the Swedish Tax Agency initially was denied leave to appeal, they opted for a new strategy to access this high income, through the fr
The focus of this thesis is to explore why petty corruption dominates and persists in Bosnian society despite the major anti-corruption efforts of Bosnian government and international organisations. By approaching corruption from a social-legal perspective, this thesis aims to explore the local experiences, social norms and morality of informal transactions in Bosnian society. To investigate these
Lagen (1982:80) om anställningsskydd, är den lag som torde vara av störst betydelse när det kommer till anställningar. Den reglerar bl.a hur en anställning ingås, vilka anställningsformer som finns och regler kring hur en anställning upphör. Från lagens tillämpningsområde undantas bl.a. personer med en företagsledande ställning och arbetsgivarens familjemedlemmar. Undantagen har motiverats med attThe Swedish law regarding the protection of employment, LAS (1982:80) is probably the most important law when it comes to employments. The law regulates how an employment is concluded, which kind of employment one may have and the rules on how employment is terminated. Persons with management positions and family members of the employer are excluded from the scope of the law. The reason that these
While carbon emissions hit an all-time high in 2019 and are expected to grow, it is important to explore strategies for reducing emissions and mitigating climate change. A potential focus for curbing emissions is the flying sector, since air travel is one of the most carbon-intensive activities an individual can engage in. Among air travelers, frequent flyers yield the highest potential for saving
I det generella begreppet våldtäkt har våld inbegripits som en självklar omständighet i många hundra år. Det har även varit ett krav i lagstiftning. I dagens sexualbrottslagstiftning är det inte längre ett krav. En våldtäkt kan begås på internet genom medgärningsmannaskap eller om det med hänsyn till kränkningens allvar är att jämföra med samlag. Av media framkommer det att detta är något unikt föFor hundreds of years, violence has been included as an integral part in the general definition of rape as well as a requirement in the legislation of rape offense charges. Today, however, violence is no longer a requirement in sexual offenses legislation. A rape can be committed on the internet through fellowship or if it is compared to sexual intercourse, given the gravity of the violation. From
Uppsatsen behandlar konflikten mellan två inte sällan kolliderande intressen, vindkraft och rennäring. I ljuset av folkrättsliga instrument till skydd för urfolk, ska samernas rätt till mark och vatten skyddas. För samer är denna rätt en förutsättning för renskötselns bedrivande, som det samiska kulturarvet i stora delar bygger på. Rennäringen förutsätter stora markområden där renar fritt kan flytThis essay discusses the conflict between wind power and reindeer husbandry, two interests which at times collide. In light of international law and its instruments for the protection of indigenous peoples, the Samis’ rights to land and water shall be protected. The right to land is a prerequisite for the Samis to pursue their reindeer herding, which lays the foundation for the cultural heritage o
The world today faces many different environmental problems, which has a negative effect. These are both global, regional and local, which means that they affect all people. To be able to overcome this and be able to promote a long-term sustainability, it is essential that all contribute and take responsibility for it. An example of doing this is to get more people to commute rather than using the
