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This chapter will analyse the Trade secret Directive from a technological informed legal perspective, looking at the possibilities and scope of protection that it offers for knowledge based activities and business models. It opens by restating the basic yet important fact that “Information is power”. Asymmetries in information are a fundamental transaction cost and in this sense informational qual
Purpose: In patients with hemophilia B, treatment with extended half-life (EHL) recombi-nant factor IX allows for longer dosing intervals while providing equal or superior bleeding protection compared with standard half-life products. This enables flexible, individualized treatment schedules, which reduce the burden of prophylaxis and improve patient outcomes. This analysis compared the efficacy o
Recently, to reach zero emission levels, some new energy systems based on fuel cells have been developed. This paper presents a review of investigations of these systems by thermodynamics performance, mainly, energy and exergy analysis. With energy analysis, the performance of an energy conversion system cannot be effectively and accurately evaluated. But exergy analysis complements and reinforces
A dry release method for fabrication of suspended nanostructures is presented. The technique has been combined with an anti-stiction treatment for fabrication of nanocantilever based nanoelectromechanical systems (NEMS). The process combines a dry release method, using a supporting layer of photoresist which is removed using oxygen ashing in a reactive ion etcher (RIE), with CHF3 plasma induced de
The nervous system is constantly infiltrated by blood-derived sentinels known as perivascular macrophages. Their immediate precursors have not yet been identified in situ and the mechanism that governs their recruitment is mostly unknown. Here, we provide evidence that CD68 (+)GR(-) monocytes can give rise to perivascular macrophages in mice suffering from endotoxemia. After adhesion to the endoth
Disturbed haemostasis is a central finding in severe Streptococcus pyogenes infection. In particular, microthrombi are found both at the local site of infection and at distant sites. Platelets are responsible for maintaining vascular function and haemostasis. We report here that M1 protein of S. pyogenes triggers immune-mediated platelet activation and thrombus formation. M1 protein is released fr
Streptococcus pyogenes (group A streptococcus) causes a variety of diseases, including acute pharyngitis, impetigo, rheumatic fever and the streptococcal toxic shock syndrome. Moreover, S. pyogenes was responsible for the classical example of a nosocomial infection, the epidemics of puerperal fever (childbed fever) that caused the death of numerous women in earlier centuries. The most extensively
This study demonstrates that a cytotoxic serum reactivity not requiring the presence of complement appears in the sera of patients with acute myelogenous leukemia. The reaction is detected upon short‐term incubation of sera in vitro with autochthonous mononuclear white blood cells from peripheral venous blood of patients at the acute stage of the disease. This reactivity was demonstrated in 18/18
Despite the recent clinical success of T cell checkpoint inhibition targeting the CTLA-4 and PD-1 pathways, many patients either fail to achieve objective responses or they develop resistance to therapy. In some cases, poor responses to checkpoint blockade have been linked to suboptimal CD28 costimulation and the inability to generate and maintain a productive adaptive anti-tumor immune response.
Memories of the transition Memories of the transition is fictive. However, it is knowledge-based speculation. Much of the story is inspired by existing proposals, emerging innovations, or research on the transformations needed to meet our climate targets. We have collected some of these imaginative seeds below so that you can understand and construct your own vision of a post-fossil society. Conte
https://www.climatefutures.lu.se/ministryofimagination - 2026-05-29
Master’s Dissertation Structural Mechanics INFLUENCE OF ANNUAL RING ORIENTATION ON COMPRESSION STRENGTH PERPENDICULAR TO GRAIN IN GLULAM Report TV SM -5203 PH ILIP W A LLIN IN FLU EN C E O F A N N U A L R IN G O R IEN TA TIO N O N C O M PR ESSIO N STR EN G TH PER PEN D IC U LA R TO G R A IN IN G LU LA M PHILIP WALLIN 5203HO.indd 15203HO.indd 1 2015-06-23 15:03:362015-06-23 15:03:36 DEPARTMENT OF C
https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5203.pdf - 2026-05-30
The gene for an IgA-binding protein from a group A streptococcal strain was cloned and expressed in Escherichia coli. The IgA-binding protein, called protein Arp, was purified on IgA-Sepharose, allowing complete purification in a single step. Analysis of protein Arp by Western immunoblotting demonstrated a major IgA-binding band, with an apparent molecular weight of 42 kD. The purified protein was
Background: A unique feature of alveolar mast cells is their low high-affinity IgE receptor (FcεRI) expression. Recent discoveries in uncontrolled asthma suggest that the appearance of FcεRI-expressing alveolar mast cells may be a novel disease-specific feature of allergic asthma. This study investigates whether increased FcεRI-expressing alveolar mast cells are present in patients with mild aller
This review compares the methodology of published clinical studies investigating the extended-half-life (EHL) factor VIII (FVIII) products, rFVIIIFc (efmoroctocog alfa, Elocta®/Eloctate®), BAY 94-9027 (damoctocog alfa pegol, Jivi®), BAX 855 (rurioctocog alfa pegol, Adynovate®) and N8-GP (turoctocog alfa pegol, Esperoct®) including the phase 2/3 studies, A-LONG (NCT01181128), PROTECT VIII (NCT01580
He was a physician, a scientist and a university vice chancellor. Kilian Stobaeus was the man whose donations formed the foundation for several University departments and museums, and the collection grew intensively over the next century. The Stobaeus Project aims to shed light on his life and achievements. Kilian Stobaeus was born on 6 February, 1690 in Vinslöv in southern Sweden to a well-educat
https://www.historiskamuseet.lu.se/stobaeus-project/who-was-kilian-stobaeus - 2026-05-29
Gerhard Schurz [2001, Journal for General Philosophy of Science, 32, 65-107] has proposed to reconstruct auxiliary hypothesis addition, e.g., postulation of Neptune to immunize Newtonian mechanics, with concepts from non-monotonous inference to avoid the retention of false predictions that are among the consequence-set of the deductive model. However, the non-monotonous reconstruction retains the
