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Background: Peripheral blood eosinophilia and lung mucosal eosinophil infiltration are hallmarks of bronchial asthma. IL-5 is a critical cytokine for eosinophil maturation, survival, and mobilization. Attempts to target eosinophils for the treatment of asthma by means of IL-5 neutralization have only resulted in partial removal of airway eosinophils, and this warrants the development of more effec

The purpose of this dissertation is to explore the heritagisation of Swedish sports, which is examined through studies of five Swedish sports museums of today. Additionally, the disseration explores the heritagisation of Swedish sports in a wider historical perspective, mainly focusing on the years between 1900 and 2000.There are plenty of sports museums in Sweden today, most of them run by amateu

The aim of this doctoral dissertation is to explore and describe the relationship and interaction between musicians and their instruments. In order to achieve a high level of detail, a certain instrument is in focus: the simple-system flute. Although primarily developed as a product of 19th- century Western art music, this instrument has since become established in other genres and traditions. Emp

This thesis concerns estimation in partially observed continuous and discrete time Markov models and focus on both inference about the conditional distribution of the unobserved process as well as parameter inference for the dynamics of the unobserved process. Paper A concerns calibration of advanced stock price models, in particular the Bates and NIG-CIR models, using options data observed thro

The aim of this doctoral dissertation is to explore and describe the relationship and interaction between musicians and their instruments. In order to achieve a high level of detail, a certain instrument is in focus: the simple-system flute. Although primarily developed as a product of 19th-century Western art music, this instrument has since become established in other genres and traditions.EmpirThe aim of this doctoral dissertation is to explore and describe the relationship and interaction between musicians and their instruments. In order to achieve a high level of detail, a certain instrument is in focus: the simple-system flute. Although primarily developed as a product of 19th-century Western art music, this instrument has since become established in other genres and traditions.Empir

This thesis delves into two ‘edge areas’ located in and around East Jerusalem. It attempts to unfold and analyze the dynamics in these edge areas, while investigating the agency of the people present there through their own perceptions and practices towards the land, the urbanization processes, the power circulation and the structural impositions. Squeezed by a settler-colonial domination that con

Idag befinner vi oss i den så kallade fjärde industriella revolutionen, ett begrepp myntat av Klaus Schwab som är grundare och styrelseordförande av World Economic Forum. Uppgifter och funktioner som tidigare förlitat sig på den mänskliga arbetskraften kan idag automatiseras och förenklas med hjälp av artificiell intelligens. Inom advokatverksamheten har artificiell intelligens använts som komplem

The purpose of this thesis was to create a dialogue between the church-sect typology of Ernst Troeltsch and the Radical Reformation theology of Arne Rasmusson. The hypothesis was that Rasmusson has good reasons to take the dialogue with Troeltsch more seriously; that the perspective of Troeltsch can help to clarify aspects of Rasmusson’s theology and show tendencies of inconsistency in it, and the

Nature sounds are often seen as relaxing, and understood as reconnecting our minds and bodies with something primeval. Such sounds are used for stress recovery in the fields of medicine and psychology, as well as in our personal meditation app downloaded on our phone. At the same time a continuous climate anxiety has invaded many personal experiences in relation to nature environments and phenomen

Over the past decade, organic–inorganic hybrid perovskites have revolutionized next-generation semiconductors, driving unprecedented advancements in cost-effective optoelectronics. While lead-based perovskite semiconductors exhibit exceptional optoelectronic properties, their inherent toxicity and vulnerability to environmental degradation remain significant barriers to widespread commercializ

Denna uppsats fördjupar sig i Louis Spohr och hans Första Konsert för Klarinett och Orkester, Op. 26, med början i en översikt över kompositörens liv och hans verk. Analysen kommer att ge en bättre förståelse för innebörden och egenskaperna hos kompositörens skrivande under hans musikaliska karriär. Uppsatsen utforskar också hur hans konsert framförs på ett sätt som ligger närmare hur kompositörenThis thesis delves into Louis Spohr and his First Concerto for Clarinet and Orchestra, Op. 26, starting with an overview of the composer's life and his work. The analysis will provide a better understanding of the meaning and characteristics of this composer's writing during his musical career. The thesis also explores the performance of his concerto that is closer to the composer’s origin

Suicide in children and young adults is a leading cause of premature mortality, and there is a need to develop a more profound understanding of the factors that contribute to these deaths. This study is part of the nationwide Retrospective Investigation of Health Care Utilization in Individuals who died by Suicide in Sweden 2015, conducted at Lund University, Sweden. The aim was to examine symptomSuicide in children and young adults is a leading cause of premature mortality, and there is a need to develop a more profound understanding of the factors that contribute to these deaths. This study is part of the nationwide Retrospective Investigation of Health Care Utilization in Individuals who died by Suicide in Sweden 2015, conducted at Lund University, Sweden. The aim was to examine symptom

Omvärldsbevakning 2023 Omvärldsbevakning 2023 LUNDS UNIVERSITET | DNR STYR 2022/2641 Bilder av Kennet Ruona, Nina Ransmyr, Johan Persson, Mikael Risedal och Charlotte Carlberg Bärg Layout och tryck av Media-Tryck, Lunds universitet, Lund 2023 Svanenmärkt trycksak, 3041 0903Tryckt av Media-Tryck, Lund 2023 Omvärldsbevakning 2023 Innehåll INLEDNING ...................................................

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2023-02/Omv%C3%A4rldsbevakning%202023.pdf - 2026-05-29

Most of the recombinant proteins produced nowadays are fused to affinity tags, in order to facilitate their purification through affinity chromato-graphy. Out the different tags available, poly-histidine tags are among the most commonly used and can help purification through immobilised metal ion affinity chromatography (IMAC). In this thesis, we present different metal binding tags, and their af

F(ab) fragments imprinted surface plasmon resonance (SPR) chip was prepared for the real-time detection of human immunoglobulin G (IgG). In order to attach polymerization precursor on SPR chip, the SPR chip surface was modified with allyl mercaptan. F(ab) fragments of the IgG molecules were prepared by papain digestion procedure and collected by fast protein liquid chromatography (FPLC) system usi

Denna uppsats behandlar de konkurrensrättsliga skillnaderna i EU-rätt och amerikans rätt rörande patentpooler. Genom patentpooler ges företag möjlighet att gemensamt samla sina patent inom ett visst tekniskt område och tillsammans licensera dem. Genom poolning av patent ökar möjligheterna för snabb utveckling samtidigt som licenskostnaderna minskar då samtliga nödvändiga patent blir tillgängliga gThis thesis identifies the differences in the antitrust regulations concerning patent pooling within the EU and the U.S. Patent pooling enables firms to jointly licence their patents as a package, gathering patents that are necessary in order to produce a certain product. Patent pooling allows faster development at lower costs, since firms can attain all necessary patents through one single licens