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OBJECTIVES: To illuminate patterns observed in International Cancer Benchmarking Programme studies by extending understanding of the various influences on presentation and referral with cancer symptoms.DESIGN: Cross-country comparison of Denmark, England and Sweden with qualitative analysis of in-depth interview accounts of the prediagnostic process in lung or bowel cancer.PARTICIPANTS: 155 women

Home care services are an important part of the Swedish social welfare system. Considering the size of the sector and the increasing future needs for home care, due to growing elderly populations, it is worrisome that problems in terms of injuries, sick leave and staff turnover appear common in this occupation. A problem for managing the situation is, however, that the current knowledgebase is fra

Background and aims: Arginase 1 deficiency (ARG1-D) is a ultrarare disease with manifestations that cause mobility and cognitive impairment that progress over time and may lead to early mortality. Diseases such as ARG1-D have a major impact also outside of the health care sector and the aim of this study was to estimate the current burden of disease associated with ARG1-D from a societal perspecti

Introduction: The COVID-19 pandemic forced leaders and employees in health care services to take difficult decisions to manage risks associated with employee health and the organizations’ functioning. This study aims to identify the changes in employee working routines, job demands, and job resources within Swedish maternal healthcare during the COVID-19 pandemic, and how these changes affected wo

Background Trauma is the leading cause of quality-related mortality in low- and middle-income countries, with an estimated two million preventable deaths each year. Although trauma quality improvement programmes have been utilised in high-income countries for more than three decades, there is no high-level evidence of their effect on patient outcomes. We aimed to assess whether implementing a cont

BACKGROUND: Though school-aged children (SAC) are at high risk of malaria, they are the ones that benefit the least from malaria prevention measures. A cluster randomized controlled trial was conducted to evaluate the effect of malaria prevention education (MPE) on insecticide-treated bed net (ITN) utilization and prompt diagnosis, reported incidence and treatment (PDAT) of malaria. Qualitative ev

Many long-term childhood cancer survivors suffer from treatment-related late effects, which may occur in any organ and include a wide spectrum of conditions. Long-term follow-up (LTFU) is recommended to facilitate early diagnosis and to ensure better health outcomes. Due to the heterogeneity of these sequelae, different specialists work together in the diagnosis and treatment of these conditions.

Multiple guidelines exist for the diagnosis and management of mitral regurgitation (MR), the second most common valvular heart disease in high-income countries, with recommendations that do not always match. We systematically reviewed guidelines on diagnosis and management of MR, highlighting similarities and differences to guide clinical decision-making. We searched national and international gui

Background. Poor maternal self-rated health in healthy women is associated with adverse neonatal outcomes, but knowledge about self-rated health in pregnant women with congenital heart disease (CHD) is sparse. This study, therefore, investigated self-rated health before, during, and after pregnancy in women with CHD and factors associated with poor self-rated health. Methods. The Swedish national

Objectives: To explore reasons for institutionalization of people with dementia according to informal caregivers as well as variation in reasons between countries. Design: An explorative cross-sectional study was conducted in 8 European countries. Setting: Per country, a minimum of 3 long term care facilities, offering care and accommodation as a package, participated in this study. Participating

Background: The Patient-Reported Indices for Multiple Sclerosis (PRIMUS) comprises a suite of three scales for assessing symptoms, activity limitations, and quality of life in multiple sclerosis (MS). It was developed in the UK and has been shown to have excellent psychometric properties. This study describes the adaptation of eight language versions for Canadian English, Canadian French, French,

OBJECTIVE: To explore whether placebo surgery controlled trials achieve what they set out to do by investigating discrepancy between projected and actual design aspects of trials identified through systematic review methods. SUMMARY BACKGROUND: Interest in placebo surgery controlled trials is growing in response to concerns regarding unnecessary surgery and the societal cost of low-value healthcar

En god hälsa är grundläggande för barns och ungas utveckling, och en förutsättning för socialt och ekonomiskt deltagande under livet. Således innebär bördan av psykisk ohälsa stora utmaningar för både individ och samhälle. Det har rapporterats att den psykiska ohälsan ökar i Sverige dels bland den yngre befolkningen, dels i vissa grupper av den vuxna befolkningen. Det finns svårigheter med att mätThe purpose of this thesis is to improve the understanding of factors related to mental ill-health, and itsdistribution, in the Swedish population. The thesis consists of four studies. In study I, we find thatbetween the years 1994 and 2011, the probability of receiving a psychiatric inpatient diagnosisincreased by 12.6 percent, while the relative and absolute income-related inequalities in diagno

BACKGROUND: This study aimed to explore the awareness, experiences, and beliefs of individuals with osteoarthritis (OA) regarding their healthcare management, along with assessing their overall satisfaction levels.METHODS: A cross-sectional online survey was conducted in Italy, Sweden, and Russia, rigorously developed based on OA international guidelines in collaboration with healthcare profession

Trollsländor i stafett över säsongen En härlig vårpromenad, citronfjärilen fladdrar förbi längs stigen och i himlen flyger tranorna trumpetande norrut. Två månader senare, samma stig. Nu är det inte citronfjärilar och tranor som möter dig, istället ser du en blågrön mosaikslända disciplinerat patrullera fram och tillbaka längs med stigen. Vad är det som gör att vi får så olika upplevelser beroeA species phenology is central to its ecology. Phenology is linked to development time and in extension size. Phenological differences can be found in both inter- and intraspecific comparisons. Sexual dimorphisms in phenology (protandry and protogyny) has been linked to sexual size dimorphism (SSD). In this study I use odonates, popular model organisms for studies of development and sexual dimorph

The labour market consequences of early-onset or congenital disabilities have received little attention in the literature. In this paper, we study the consequences of cerebral palsy (CP), a lifelong early onset disability, and pathways through which it affects labour outcomes. We use data from multiple linked Swedish National Population Registers between 1990 and 2015 and apply both regression and

Spine Computed Tomography (SCT) is essential for identifying fractures, tumors and degenerative spine diseases, assisting medical practitioners in formulating an accurate diagnosis and treatment. One of the core element of SCT is reporting. The effectiveness of spine reporting is often limited by challenges such as an inadequate infrastructure and lack of experts. Automated SCT analysis has the po

Popular Abstract in Swedish Cystisk Fibros Cystisk Fibros (CF) är en relativt vanlig ärftlig sjukdom. Ungefär 1/37 personer i Sverige bär på anlag till CF, men bärare har inga symptom och vet därför inte att de har anlagen. För att få sjukdomen måste fostret få två anlag, ett från vardera föräldern, vilket är 25% risk vid varje graviditet för föräldrapar där båda är bärare. CF är en dödlig sjukdomCystic Fibrosis (CF) is a severe hereditary disorder leading to progressive deterioration of lung function and death. This thesis describes the demography of CF in Sweden, its treatment, with special reference to physiotherapy, and its effects on lung function and peak working capacity (PWC). The study is based on Swedish CF patients and evaluates our current CF treatment package, which differs fr

D EV EL O PM EN T 507RESEARCH ARTICLE INTRODUCTION The mesencephalic dopaminergic (mesDA) neurons have been studied extensively owing to their involvement in Parkinson’s disease, as well as in psychiatric and affective disorders. The mesDA neurons are located in the substantia nigra (SN, cell group A9), the ventral tegmental area (VTA, cell group A10) and the retro-rubral area (RRA, cell group A8)

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/andersson_et_al_development_2006.pdf - 2026-05-07