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IntroductionThere is a gap in knowledge regarding development of endometriosis and adenomyosis lesions visible at transvaginal ultrasound. The objectives were to evaluate if women with symptoms suggestive of endometriosis or adenomyosis but normal ultrasound examination develop endometriosis or adenomyosis lesions visible at ultrasound over time and if alterations of symptoms over time are associa

Background: As part of I-O Optimise, a multinational research platform providing real-world insights into the management of lung cancers, the SCAN-LEAF study aims to describe the epidemiology, clinical care and outcomes for pts with NSCLC in Scandinavia. We report initial Tx and OS for pts with NSCLC prior to the availability of immunotherapies in Sweden. Methods: The analysis includes all adult p

Uppsatsen handlar om hur den svenska lagstiftningen påverkades av den nationalsocialistiska utvecklingen som skedde i Tyskland under åren 1920 – 1945. Den antar ett historiskt utvecklingsperspektiv och är uppdelad i två delar. Den första delen ger en allmän bakgrund samt pekar på de nazistiska rösterna i den svenska politiken vid den aktuella perioden och definierar begreppet nazism. Den andra delThis essay is about how the Swedish legislation was influenced by the development of the National Socialism in Germany during the years 1920 – 1945. The essay will take on a historical development perspective and is divided into two parts. The first part gives a general background and highlights the Nazi voices in the Swedish politics at this current period and defines the concept of Nazism. The s

Background: There are several risk factors for the colonisation, infection and spreading of antibiotic resistant bacteria among elderly residents of nursing homes. An updated estimate of the native prevalence of antimicrobial resistance in uropathogens among Swedish nursing home residents is needed. Methods: Urine specimens were collected for culture and antimicrobial susceptibility testing agains

Background: Ingestion of a meal increases the blood flow to the gastrointestinal organs and affects the heart rate (HR), blood pressure and cardiac output (CO), although the mechanisms are not known. The aim of this study was to evaluate the effect of endogenously released glucose, insulin, glucagon-like peptide 1 (GLP-1), ghrelin on CO, HR, stroke volume (SV), and blood pressure. Methods: Eleven

Background: High expression of the polymeric immunoglobulin receptor (PIGR) has previously been associated with a favourable prognosis in a few cancer forms, but its expression and relationship with clinical outcome in epithelial ovarian cancer (EOC) has not yet been reported. The aim of this study was therefore to examine the clinicopathological correlates and prognostic significance of PIGR expr

Objective The complex genetic aetiology underlying irritable bowel syndrome (IBS) needs to be assessed in large-scale genetic studies. Two independent IBS cohorts were genotyped to assess whether genetic variability in immune, neuronal and barrier integrity genes is associated with IBS. Design 384 single nucleotide polymorphisms (SNPs) covering 270 genes were genotyped in an exploratory cohort (93

The aim of this project is to explore and understand the combustion phenomenon in engines operating on gaseous fuels, and develop technologies as an alternative to the present diesel engine technologies for heavy duty applications; which are facing severe challenges like stringent emissions norms, high technology costs and unsustainable fuel supply. The studies presented in this thesis focus on th

The 20q13 region is frequently amplified/overexpressed in breast tumours. However, the nature of this amplification/overexpression is unknown. Here, we investigated genetic variation in five 20q13 amplicon genes (MYBL2, AURKA, ZNF217, STK4 and PTPN1) and its impact on breast cancer (BC) susceptibility and clinical outcome. As a novel finding, four polymorphisms in STK4 (rs6017452, rs7271519) and A

Objective . Low density lipoprotein cholesterol (LDL-C) is an independent and modifiable risk factor for development of cardiovascular disease (CVD). Postprandial lipid metabolism has been linked to CVD, but little is known about the postprandial LDL-C profile in patients with type-2 diabetes (T2DM). We aimed to study the postprandial levels of LDL-C in T2DM patients. Material and methods . After

In experimentally induced myocardial ischemia, mild hypothermia (33-35 degrees C) has a robust cardioprotective effect. Tissue plasminogen activator (t-PA) is a profibrinolytic enzyme that is released from the vascular endothelial cells in response to ischemia and other injurious stimuli. t-PA has also been found to have proinflammatory properties that could contribute to reperfusion injury. We po

Background: While simultaneous saccharification and co-fermentation (SSCF) is considered to be a promising process for bioconversion of lignocellulosic materials to ethanol, there are still relatively little demo-plant data and operating experiences reported in the literature. In the current work, we designed a SSCF process and scaled up from lab to demo scale reaching 4% (w/v) ethanol using xylos

AIMS: Atrial fibrillation cycle lengths can be assessed from right precordial ECG leads and the unipolar oesophageal ECG using a non-invasive method called Frequency Analysis of Fibrillatory ECG. The purpose of this report is to present the results from application of this method in a large group of patients with long-term atrial fibrillation and to examine the differences between patients with 'c

Fedorowski A, Hedblad B, Engstrom G, Gustav Smith J, Melander O (Department of Clinical Sciences, Lund University, Malmo; and Skane University Hospital, Malmo, Sweden). Orthostatic hypotension and long-term incidence of atrial fibrillation: the Malmo Preventive Project. J Intern Med 2010; 268: 383-389. Objectives. Orthostatic hypotension (OH), a common manifestation of autonomic dysfunction, has b

OBJECTIVE: To investigate effects of lipid lowering drug, simvastatin, on apolipoprotein M expression in the hyperlipidemic mice and in hepatic cell line, HepG2 cells. METHODS: Swiss male mice were randomly divided into the high fat group and control group, and were intragastrically fed with 0.9% saline (control group) or lipid emulsion (high fat group) at the daily dosage of 15 ml/kg body weight

Miljö- och klimatfrågor blir alltmer aktuella i samhället. Såväl konsumenter som företag och internationella organisationer lägger större fokus på dessa frågor. Exempelvis använder företag ofta miljöpåståenden i sin marknadsföring, det vill säga påståenden som skapar intrycket att en produkt har en positiv inverkan, saknar inverkan eller har en mindre inverkan på miljön än andra produkter. DärtillEnvironmental and climate issues are becoming increasingly relevant in society. Both consumers and companies, as well as international organizations are placing greater focus on these issues. For example, companies often use environmental claims in their marketing, making statements that create the impression that a product has a positive impact, no impact or a lesser impact on the environment com

The current conflict in Syria has resulted in a major refugee disaster. The lack of legal refugee routes to Europe is forcing refugees to hire smugglers to escape war in their homeland. They are often forced to pay large sums of money for the hazardous journey across the Mediterranean Sea and further through Europe. These journeys are often far stretched and not many are successful. Due to the war

Neoliberalism, as a loosely defined set of political beliefs, calls for more individual freedom and autonomy, resulting in increased responsibility for each person to address major societal issues. ‘Individualization’ is the process by which responsibility for addressing major environmental issues such as climate change is placed on individuals. In this thesis I investigate whether individualizati

Av artikel 8 i Europeiska konventionen om skydd för de mänskliga rättigheterna och de grundläggande friheterna (nedan Europakonventionen) följer att alla och envar som befinner sig inom en konventionsstats jurisdiktion ska tillförsäkras en rätt till familjeliv. Innebörden av rättigheten är framför allt att den enskilde åtnjuter ett skydd mot ingripanden från det offentliga som kan utgöra en kränknArticle 8 of the European Convention for the Protection of Human Rights and Fundamental Freedoms (hereinafter referred to as the European Con-vention) states that everyone within the jurisdiction of a Contracting State shall be guaranteed a right to family life. The meaning of the right is above all that the individual enjoys protection against interference from the public sector which may constit