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Background: Type 2 diabetes (T2D) is a complex disease characterised by chronic hyperglycaemia. The effects of elevated glucose on global gene expression in combination with DNA methylation patterns have not yet been studied in human pancreatic islets. Our aim was to study the impact of 48 h exposure to high (19 mM) versus control (5.6 mM) glucose levels on glucose-stimulated insulin secretion, ge
A commercially available NaI(Tl) based spectrometer-dosimeter has been used to separate contributions of the terrestrial radionuclides (238U series, 232Th series and 40K) and 137Cs to the total ambient dose equivalent rate (ADER), Ḣ*(10) , outdoors. The device had been initially calibrated by the manufacturer to measure: 1) the total ADER; 2) activity concentrations of 226Ra, 232Th, 40K and ‘effec
Background: High levels of blood glucose are thought to be associated with colorectal cancer (CRC) and hyperinsulinemia, an interstage in the development of CRC. The purpose of this study was to examine associations between incident CRC and blood glucose; plasma insulin; and the homeostasis model assessment for insulin resistance (HOMA2-IR), respectively, and to determine whether these association
Pancreatic polypeptide (PP) is a gut-derived hormone of the neuropeptide Y family that regulates appetite, gastrointestinal motility, and energy homeostasis through activation of the neuropeptide Y4 receptor (Y4R). With the rising prevalence of obesity, understanding the molecular pharmacology and structure-function relationships of PP-Y4R interactions is essential for the development of novel ant
Through the tight link between plants and their pollinators, plant species often decline when their pollinators decline and vice versa. These nominal declines are well studied for many plant-pollinator networks. Less well known is the effect that the decline of a plant species has on the behaviour of its pollinators, and how potential changes in pollinator behaviour affect the reproductive success
Sammanfattning Examensarbetets titel: Två sidor av ett mynt - kontroll i ett tillitsbaserat ledarskap Seminariedatum: 11 januari 2024 Kurs: FEKH49 - Examensarbete i organisation på kandidatnivå, 15 högskolepoäng Författare: Anna Depui Ekdal, Beatrice Jensen och Alba Aliu Handledare: Nadja Sörgärde Nyckelord: Tillit, kontroll, tillitsbaserat ledarskap, distansarbete, chefskap Forskningsfrågor: “Abstract Title: Two sides of the same coin - control in trust-based leadership. Seminar date: January 11th 2024 Course: FEKH49 - Bachelor’s degree thesis in Management and Organization, 15 credits Authors: Anna Depui Ekdal, Beatrice Jensen och Alba Aliu Supervisors: Nadja Sörgärde Keywords: Trust, control, trust-based leadership, remote work, managerial work. Research question: “How do manage
Låneförbuden i den svenska aktiebolagslagen (ABL) utgör kapitalskydds-regler och innefattar två separata förbudsbestämmelser. Först, ett generellt låneförbud, ofta benämnt som förbudet mot närståendelån, som specificeras i 21 kap. 1§ ABL. Detta förbud hindrar aktiebolag från att låna ut pengar till exempelvis styrelsemedlemmar, aktieägare i bolaget, eller andra bolag inom samma koncern. För det anThe loan prohibitions in the Swedish Aktiebolagslagen (ABL) constitute capital protection rules and mainly encompass two separate prohibition provisions. First, a general loan prohibition, often referred to as the prohibi-tion against loans to related parties (närståendelåneförbudet), which is specified in ABL chapter 21, section 1. This prohibition prevents Swedish limited companies (Sw. aktiebol
Både Sveriges rättsväsende och makthavare gjorde avsteg från gällande processrätt på 1600-talet. Den samtida lagstiftningen uppställde stränga regler för rättegången, bevisvärderingen och straffen. Trolldom hade utgjort ett brott enligt lagstiftningen sedan medeltiden. Med förändringar inom rättsväsendet utökades brottet, samtidigt som anklagelser om Blåkullafärder och djävulspakter spred sig övBoth the Swedish Judiciary and rulers made deviations from applicable procedural law in the 17th century. The contemporary legislation set up strict rules for the trial, the evaluation of evidence, and the punishment. Sorcery had constituted a criminal offense according to the law since the Middle Ages. With changes within the Judiciary, the crime was expanded, while accusations of journeys to Bl
Cities today globally face significant problems in the context of the climate crisis. Firstly, in terms of resilience in enduring future challenges – urban heat islands, increasingly frequent flooding, supply chain disruptions, sea level rise among others. Secondly, in terms of contributing to said crisis, through carbon emissions, the erosion of biodiversity through sprawl, overconsumption, and c
Bacterial cellulose (BC) is a versatile and biocompatible polysaccharide produced by bacteria, with Komagataeibacter xylinus being the model species for its production. This polymer has unique properties that make it valuable in several applications, including as a rheology modifier in cosmetics. Cellugy, a Danish start-up, produces EcoFLEXY, a BC-based rheology modifier that enhances the viscosit
The last mass-extinction event happened over 65 million years ago when an asteroid collided with earth, resulting in the loss of 76% of all species. Scientists now warn that we are on the precipice of a new mass-extinction, the responsibility of which can be placed entirely on one species, the homo sapiens. While some species of birds, bats, and arthropods are especially vulnerable, we are all int
Our decisions from the past affect the present time. The same is true of the decisions we make today. How do we want to see our local environment in the future? In the western part of Iceland there is an island called Brákarey. Brákarey is connected via bridge to the town of Borgarnes. Brákarey has played a variety of roles over the past years, but transport of people and goods was one of its bigg
This thesis investigates how place can be understood through assemblage theory and what that implies for the understanding of human relation to place. The framework has been widely used outside and within human geography, at a few instances related to place. Exploring place as assemblage is done through a case study of S:t Pauli cemeteries in Malmö. Main methods are walk along interviews and obser
III-V semiconductors are a profound part of the optoelectronics industry and new developments in alloy compositions and architectures are constantly emerging. Lowdimensional semiconductors, such as nanowires (NWs) have shown to have improved characteristics in certain areas such as enhanced light absorption and can furthermore be integrated on Silicon (Si) plattforms and are thus predicted to be a
As the demand for eco-friendly alternatives to traditional plastics grows, Polyethylene Furanoate (PEF) emerges as a promising solution. Derived from renewable biomass sources, PEF embodies sustainability principles by reducing reliance on finite resources and minimizing environmental impact. PEF is synthesized from 2,5-furandicarboxylic acid (FDCA), a key monomer which upon polymerization has the
I Sverige finns många förorenade områden med klorerade lösningsmedel och Färgaren 3 i Kris-tianstad är ett av dem. Där har tidigare legat en kemtvätt som använt sig av PCE (Tetrakloreten), där spill och läck-age har förorenat stora delar av fastigheten. PCE och dess metaboliter har en tendens att förorena stora volymer, vilket gör dessa ämnen svåra att sanera. Detta mastersarbete inriktar sig på a
A large share of the existing building stock in Sweden originates from the so-called Million Building Programme, a large-scale construction wave between 1965 and 1974 to tackle the housing shortage at this time. Those buildings have very high energy demand and require renovation due to age and often neglected maintenance. The Swedish government’s long-term climate and energy goals are tied to an e
