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BackgroundThe incidence of human papilloma virus (HPV)-related oral cancer has recently increased worldwide. The role of dentists is of prime importance in the early detection of oral cancer which would result in a favourable outcome for the patients. The aim of the current study was to assess the knowledge, awareness and attitudes of dental students, interns and postgraduate maxillofacial residen
Considering the growth in urbanization, leading to an increase in impervious surfaces, and the changing climate, enhancing the intensity and frequency of rainfall events, existing urban drainage networks—separate or combined sewer systems—are presumed to face substantially elevated hydraulic loads, causing pluvial floods in urban areas. There are several ways to address these challenges. Cities ca
1. Neuropeptide Y (NPY) and peptide YY (PYY) act at receptors referred to as Y1 and Y2, while the Y3 receptor is specific to NPY and does not recognize PYY. The effects of NPY, its related peptides and a series of newly constructed chimeric NPY-PYY peptides were examined on excitatory and inhibitory postsynaptic currents (e.p.s.cs and i.p.s.cs, respectively) in rat dorsomedial nucleus tractus soli
An extended version of a numerical model introduced by Larson et al. (2013) to simulate long-term cross shore material exchange for the subaqueous portion of the profile has been developed. Efforts have focused on improving the model to better account for beach systems consisting of two bars (inner and outer bar), as well as simulating the feeder response over time of nearshore dredged material ba
PURPOSE: The R2Pulm trial was conducted to evaluate the effect of busulfan-melphalan high-dose chemotherapy with autologous stem-cell rescue (BuMel) without whole-lung irradiation (WLI) on event-free survival (main end point) and overall survival, compared with standard chemotherapy with WLI in Ewing sarcoma (ES) presenting with pulmonary and/or pleural metastases. METHODS: From 2000 to 2015, we e
Microstructure and crystallographic texture are the key factors that determine the properties of sputtering target used in integrated circuit fabrication. Multi-pass clock-rolling has been used recently to produce Ta sputtering targets. However, the effect of strain per pass, or the number of passes to achieve desired thickness, in clock-rolling on the homogeneity of final microstructure has not b
Accurately quantifying soil base cation pool sizes is essential to interpreting the sustainability of forest harvests from element mass-balance studies. The soil-exchangeable pool is classically viewed as the bank of "available" base cations in the soil, withdrawn upon by plant uptake and leaching and refilled by litter decomposition, atmospheric deposition and mineral weathering. The operational
BACKGROUND: Most evidence for TSC-associated neuropsychiatric disorders (TAND) to date have come from small studies and case reports, and very little is known about TAND in adults. We explored baseline TAND data from the large-scale international TOSCA natural history study to compare childhood and adult patterns, describe age-based patterns, and explore genotype-TAND correlations.RESULTS: The stu
The importance of semi-arid ecosystems in the global carbon cycle as sinks for CO 2 emissions has recently been highlighted. Africa is a carbon sink and nearly half its area comprises arid and semi-arid ecosystems. However, the
Phosphatocopids are a group of small extinct marine crustaceans, which occur widespread in Cambrian dysoxic benthic lithofacies. Whereas the anatomy of the earliest ontogenetic stages of phosphatocopids, from the head larva with four pairs of appendages onward, is well documented, that of more advanced or adult growth stages has remained almost unknown (except for the external shields). Here we de
Objectives To identify the genetic determinants of fracture risk and assess the role of 15 clinical risk factors on osteoporotic fracture risk. Design Meta-analysis of genome wide association studies (GWAS) and a two-sample mendelian randomisation approach. Setting 25 cohorts from Europe, United States, east Asia, and Australia with genome wide genotyping and fracture data. Participants A discover
OBJECTIVE: Resistance to androgens has been suggested as a possible cause of male infertility. This hypothesis is based mainly on binding studies in genital skin fibroblasts but the molecular evidence is sparse. DESIGN: Molecular studies of the androgen receptor gene were performed in 10 azoo- or oligozoospermic men, precenting with clinical signs of low androgen activity - poor virilization and h
Excessive accumulation of leukocytes in the lung represents a key feature in the development of an acute lung injury (ALI). Numerous studies demonstrated that leukocyte rolling is a compulsory precondition for the firm adhesion in organs. However, it seems that the recruitment process of leukocytes in the lung is more complex. Increasing evidence suggests that recruitment of leukocytes in pulmonar
Inom kärnkraftsindustrin är säkerhet den aspekt som prioriteras högst. Alla kärnkraftverk är designade för att i högsta möjliga mån förhindra läckage av radioaktivetet till omgivningen, både under drift och i händelse av en allvarlig olycka. Med anledning av detta är reaktorinneslutningens vägg en av de viktigaste säkerhetsrelaterade konstruktionerna vid en anläggning, detta då denna konstruktionSafety is the top priority at a nuclear facility. The nuclear power plants are designed to prevent radioactive leakage to the surroundings, both during normal operation as well as in case of a severe accident. One of the most important structures in a nuclear power plant, with regard to safety, is thus the reactor containment wall. The containment wall is the last main barrier to prevent radioacti
Although bottom water hypoxia (O2 −1) is presently widespread in the Baltic Sea coastal zone, there is a lack of insight into past changes in bottom water oxygen in these areas on timescales of millennia, and the possible driving factors. Here, we present a sediment-based environmental reconstruction of surface water productivity, salinity and bottom water oxygen for the past 5400 years at Gåsfjär
Peak bone mass is normally reached in the third decade of life. Previously, in the population-based PEAK-25 cohort (n = 1061, age 25.5 ± 0.2), we demonstrated that bone mineral density in the population-based PEAK-25 cohort is comparatively high; therefore, this study aimed to determine if the calcaneus microarchitecture mirrored this. In the process, we describe normative quantitative ultrasound
