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Popular Abstract in Swedish I dag används cellhämmande medel, cytostatika, ofta i kombination med andra metoder för behandling av vissa typer av cancer. Cytostatika kan bota t.ex. leukemi, testikel- och lymfkörtelcancer, eller lindra symtomen och förlänga livet vid t.ex. småcellig lungcancer. En grupp av cytostatika utgörs av metallkomplex där metallen är platina (Pt). Upptäckten av en sådan förenThe kinetics and mechanism for interactions of the anticancer active platinum(II) complexes cis-[PtCl2(NH3)2)], cis-[PtCl2(NH3)(c-C6H11NH2)], and trans-[PtCl2-(NH3)(quinoline)] with DNA have been studied using a combination of HPLC, circular dichroism (CD), UV/vis spectroscopy, and differential scanning calorimetry (DSC). Reactions of the monoaqua forms (charge = +1) of these complexes with single

The dissertation can be divided into two parts, the first of which is a detailed analysis of three excavations concerning Mellanbyn in southern Malmö. In the second part I study the more general development of society, relating Mellanbyn to the surrounding area as well as to the region as a whole during Late Bronze Age and the Early Iron Age. The aim can be summed up as being to study the developm

My thesis is part of an overall environmental program evaluating the environmental and human health stress in areas of Nicaragua affected by anthropogenic emission of metals and man-made organic substances. I examine the fluvial transport of mercury contextually associated with the extent of the contamination and the observed human and environmental stress in a gold mining area. Field measurements

Popular Abstract in Swedish Evolusjon og energikonservering i en katalysator i cellens kraftverk Alle levende organismer må omforme energien i mat eller sollys til en form som cellen kan bruke som energi. Energien brukes både til prosesser som bryter ned og bygger opp komponenter i cellen. Den brukes også til prosesser som muskelsammentrekninger, celledelinger og bevegelser. Uansett hva slags cel

Chancroid caused by Haemophilus ducreyi, has been described as a significantly predisposing factor of HIV heterosexual transmission in an endemic region of both diseases. Antibiotic resistances are extensively found in H. ducreyi and many of the resistances are due to the presence of resistance plasmids. A high tendency of drug resistances has commonly been found among isolates derived in Thailan

The use of topographical data in hydrological and agricultural applications has increased with GPS data availability and the concept of precision agriculture. This thesis investigates the relationships between topography and in one case simulated soil moisture and in the other case yield. The yield was recorded with a new optical sensor, which uses a digital camera to detect objects and records th

BACKGROUND AND AIMS: Autoantibodies against the zinc transporter 8 (ZnT8A) are common in type 1 diabetes (T1D). ZnT8A analyses are complicated by the fact that there are three variants of the autoantigen at amino acid position 325 representing ZnT8-R (Arginine), ZnT8-W (Tryptophan) and ZnT8-Q (Glutamin). The aims of the study were: 1) to develop an autoantigen triple mix Radio-Binding Assay (RBA)

Popular Abstract in Swedish I denna avhandling presenteras fyra nya metoder för att automatiskt mäta hjärtats förmåga att pumpa ut blod i kroppen, mäta storleken på en hjärtinfarkt samt mäta hur stor del av hjärtmuskeln som riskerade att dö vid hjärtinfarkten. Dessa nya metoder kan användas för att minska skillnader mellan mätningar gjorda av olika läkare, på olika sjukhus och i olika forskargruppIn this thesis four new algorithms are presented for automatic segmentation in cardiovascular magnetic resonance (CMR); automatic segmentation of the left ventricle, myocardial infarction, and myocardium at risk in two different image types. All four algorithms were implemented in freely available software for image analysis and were validated against reference delineations with a low bias and hig

This study investigates pathways by which the eicosanoid precursor pools in the platelets, bone marrow and the gastrointestinal (GI) mucosa are acquired and regulated, and in this context some aspects on the interaction between triglyceride (TG)-rich lipoproteins and platelets. 1. Platelets take up chylomicrons (CM) in vitro, the main part being sequestered in open canalicular system and not degr

Precipitation is often the sole source of water replenishment in arid and semi-arid areas and, thus, plays a pertinent role in sustaining desert ecosystems. Revegetation over 40 years using mainly Artemisia ordosica and Caragana korshinskii at Shapotou Desert Experimental Research Station near Lanzhou, China, has established a dwarf-shrub and microbiotic soil crust cover on the stabilized sand dun

Declining biological production as a part of an ongoing land degradation process is considered a severe environmental problem in the dry northern and northwestern regions of China. The aim of this study is to develop and adapt a satellite data-driven gross primary production model called Lund University light use efficiency model (LULUE) to temperate conditions in order to map gross primary produc

Background and objectives In accordance with clinical findings, myringoscterosis develops after otitis media (OM) and paracentesis in an experimental setting. The pathogenesis of this phenomenon of calcification is poorly understood. As the calcification process and the sclerotic plaques of the drum mimics features of bone tissue, this study explores tympanic membrane calcium deposition in associa

Arsenic enrichment of groundwater in the Red River (Song Hong) delta in Vietnam was discovered in 1998. Several studies performed in this area found concentrations of As exceeding the WHO-guideline of 10 lg/L. This study focuses on an area south of Hanoi city, Nam Du, where a new well field came into operation in 2004. The new well field is situated on the bank along the Red River in order to faci

Association studies were carried out on a sample of 87 patients from Sweden who had survived a myocardial infarction (MI) at a young age and 93 age-matched healthy individuals, to compare the impact of polymorphisms (PvuII, HindIII and Serine447-Stop) at the lipoprotein lipase (LPL) gene locus on among-individual differences in plasma lipid traits and progression of atherosclerosis. Significant li

The effect of plant species diversity on productivity and competitive ability was studied in an experiment carried out simultaneously in five European countries: Czech Republic (CZ), the Netherlands (NL), Sweden (SE), Spain (SP), and United Kingdom (UK). The aim was to separate the 'chance' or 'sampling effect' (increasing the number of sown species increases the probability that a species able 't

1 Plant species differ in their capacity to influence soil organic matter, soil nutrient availability and the composition of soil microbial communities. Their influences on soil properties result in net positive or negative feedback effects, which influence plant performance and plant community composition. 2 For two grassland systems, one on a sandy soil in the Netherlands and one on a chalk soi

The book contains selected articles from research in different areas produced by scientists in Scandinavia. However, many of the articles are based upon professor Göran Fagerlund's original ideas. Titles:

1.Cementitious injection grouts - penetration ability (Alemo, J. & Hansson, P.).
2.A disadvantage of high performance concrete and a simple way to avoid it (Alexanderson, J).

Element cycling and nutrient supply in forest ecosystems are of vital importance for short-term productivity and for longer-term land management in terms of nutrient leaching and CO2 fixation. This thesis includes a series of studies with the objective of modelling some aspects of the effect of acidification and climate change on element cycling and nutrient supply in forest soil. A reconstructio