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Background: Both single factors and composite measures have been suggested to predict mortality in patients with chronic obstructive pulmonary disease (COPD) and there is a need to analyze the relative importance of each variable. Objective: To explore the predictors of mortality for patients with COPD in relation to respiratory, cardiac, and malignant causes, as well as all causes of death. Metho
Importance: The concept of embolic stroke of undetermined source (ESUS) unifies a subgroup of cryptogenic strokes based on neuroimaging, a defined minimum set of diagnostic tests, and exclusion of certain causes. Despite an annual stroke recurrence rate of 5%, little is known about the etiology underlying recurrent stroke after ESUS. Objective: To identify the stroke subtype of recurrent ischemic
Aims/hypothesis: The risk of complications and medical consequences of type 2 diabetes are well known. Hospital costs have been identified as a key driver of total costs in studies of the economic burden of type 2 diabetes. Less evidence has been generated on the impact of individual diabetic complications on the overall societal burden. The objective of this study was to analyse costs of hospital
Background: Acute coronary syndromes most commonly arise from thrombosis of lipid-rich coronary atheromas that have large plaque burden despite angiographically appearing mild. Objectives: This study sought to examine the outcomes of percutaneous coronary intervention (PCI) of non–flow-limiting vulnerable plaques. Methods: Three-vessel imaging was performed with a combination intravascular ultraso
Background: 27-Hydroxycholesterol (27HC) stimulates estrogen receptor-positive (ER+) breast cancer (BC) progression. Inhibiting the sterol 27-hydroxylase (CYP27A1) abrogates these growth-promoting effects of 27HC in mice. However, the significance of CYP27A1 expression on BC biology and prognosis is unclear. Methods: Intratumoral CYP27A1 expression in invasive BC was measured by immunohistochemist
Background: Neuropsychiatric symptoms (NPS) are common in individuals with Alzheimer’s disease (AD) dementia, but substantial heterogeneity exists in the manifestation of NPS. Sex differences may explain this clinical variability. We aimed to investigate the sex differences in the prevalence and severity of NPS in AD dementia. Methods: Literature searches were conducted in Embase, MEDLINE/PubMed,
Importance: Although tramadol is increasingly used to manage chronic noncancer pain, few safety studies have compared it with other opioids. Objective: To assess the associations of tramadol, compared with codeine, with mortality and other adverse clinical outcomes as used in outpatient settings. Design, Setting, and Participants: Retrospective, population-based, propensity score-matched cohort st
Importance: Supplementing preterm infants with long-chain polyunsaturated fatty acids (LC-PUFA) has been inconsistent in reducing the severity and incidence of retinopathy of prematurity (ROP). Furthermore, few studies have measured the long-term serum lipid levels after supplementation. Objective: To assess whether ROP severity is associated with serum levels of LC-PUFA, especially docosahexaenoi
Aims: Because evidence regarding risk stratification predicting prognosis of patients with heart failure (HF) decompensation attended in primary care is lacking, we developed and externally validated a model to forecast death/hospitalization during the first 30 days after an episode of decompensation. The predictive model is based on variables easily obtained in primary care settings. Methods and
I denna rapport redovisas populationstrender för 208 svenska fågelarter för olika långa tidsperioder. Fåglarna har räknats vinter, vår och sommar enligt strikt standardiserade metoder. Sommarrespektive vinterpunktrutter har räknats sedan 1975, i huvudsak i södra Sverige. Standardrutterna räknas också på sommaren (sedan 1996) men täcker hela Sverige på ett representativt sätt. Nattaktiva fåglar harWe present the results of the Swedish Bird Survey, run by the Department of Biology, Lund University, as a part of the National Monitoring Programme of the Swedish Environmental Protection Agency. The results for 2017 include data from: 575 winter point counts in 2016/2017 (42nd winter), of which 284 were carried out during the Christmas/New Year count, 223 summer point count routes (43rd year) an
Objective: To determine the role of inflammatory biomarkers at 2 years post–anterior cruciate ligament (ACL) injury to predict radiographic knee osteoarthritis (OA) and magnetic resonance imaging (MRI)–defined knee OA at 5 years postinjury, with a secondary aim of estimating the concordance of inflammatory biomarkers assessed by MRI and synovial fluid (SF) analysis. Methods: We studied 113 patient
Background: Ovarian tumours are usually surgically removed because of the presumed risk of complications. Few large prospective studies on long-term follow-up of adnexal masses exist. We aimed to estimate the cumulative incidence of cyst complications and malignancy during the first 2 years of follow-up after adnexal masses have been classified as benign by use of ultrasonography. Methods: In the
BACKGROUND: Sacroiliac joint pain is increasingly recognized as a cause of low back pain. We compared the safety and effectiveness of minimally invasive sacroiliac joint arthrodesis using triangular titanium implants and conservative management in patients with chronic sacroiliac joint pain. METHODS: This study was a prospective, multicenter randomized controlled trial of adults with chronic sacro
BACKGROUND: Patients with diabetes have increased rates of major adverse cardiac events (MACEs). We hypothesized that this is explained by diabetes-associated differences in coronary plaque morphology and lipid content. METHODS: In PROSPECT II (Providing Regional Observations to Study Predictors of Events in the Coronary Tree), 898 patients with acute myocardial infarction with or without ST-segme
Narcissister förknippas bland annat med ”narcissistisk misshandel”, en bild som sprids av YouTube-kanaler som primärt publicerar videos berörande detta ämne. En netnografisktematisk analys utfördes på kommentarsfältet tillhörande en sådan video, med rubriken ”Why do you feel it so important to know they are definitely a narcissist?”. Detta i mål om att studeras hur ”görandet” av stigma, i form av
Denna uppsats är en kulturanalys av ett arkiv. Uppsatsen bidrar till utökad förståelse för det nukleära kulturarvet. Det empiriska materialet är dokument från den anti-nukleära rörelsen i Franska Polynesien och dess försök att stoppa Franska atombombsprovsprängningar där. Mitt arbete med att registrera materialet utgör ett led i analysen. Dokumenten är insamlade av ett aktivistpar: akademikern ochThis thesis is a cultural analysis of an archive that contributes to the understanding of nuclear culture and heritage. The empirical material are documents from the anti-nuclear movement in French Polynesia and the archiving process of these documents. The documents are collected by an activist couple: Swedish scholar and adventurer Bengt Danielsson and his wife Marie-Thérèse Danielsson. The prob
Syftet med denna masteruppsats är att undersöka hur fysisk aktivitet och social interaktion bidrar till bättre prestationsförmåga av den åldrande kroppen. Studien är baserad på etnografiskt material som samlades in från januari till februari 2018 på ett träningscenter som heter Gerdahallen, beläget i Lund, Sverige. Det huvudsakliga empiriska materialet består av inspelade och transkriberade semi-sThe aim of this thesis is to investigate how physical activity and social interaction assist in generating better performance of the ageing body. A multifaceted ethnographic material was collected from January to February 2018 at a health and training centre called Gerdahallen, located in Lund, Sweden. The main empirical material consists of recorded and transcribed semi-structured in-depth interv
Öresundsregionen är idag Nordens största transnationella samarbetsregion och omfattar hela Skånes län samt östra delen av Danmark. Sedan öppningen av Öresundsbron, år 2000, har regionen varit den arbetsmarknad som vuxit hastigast i Sverige och placerar sig betydligt högre upp än Stockholm på listan. Dock kan man inte se Öresundsregionen som en funktionellt integrerad enhet än. Ett närmare samarbetÖresund Region is, as of today, the biggest transnational region in Scandinavia. The inauguration of the Öresund Bridge in the year 2000 can be seen as the starting point of the regions rapid growth which has led to its surpassing of Stockholm in size. However, it has yet to fully function as an integral unit and a closer relationship between the economies is crucial for reaching a maximum of its
I denna uppsats ser vi vad som händer när en statlig myndighet som ansvarar för utformning av offentlig miljö implementerar en så kallad liberal demokratiteori. Statens konstråd, som är en myndighet med stor inverkan på den offentliga konsten i Sverige, inledde 2012 ett nytt arbetssätt att föra ut konceptuell och samtida konst från institutioner och gallerier till det offentliga rummet. Deras syn
