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Background: Squamous cell cancer of the anus (SCCA) is a rare malignancy, but the incidence is increasing. It isassociated with humman papilloma virus infection. The standard treatment is radiotherapy (RT) combined withchemotherapy, usually 5-fluorouracil (5FU)/Mitomycin C (MMC). This treatment is relatively effective, butrecurrence still represents a problem especially in locally advanced SCCA.Th
The GHG-CCI project is one of several projects of the European Space Agency's (ESA) Climate Change Initiative (CCI). The goal of the CCI is to generate and deliver data sets of various satellite-derived Essential Climate Variables (ECVs) in line with GCOS (Global Climate Observing System) requirements. The "ECV Greenhouse Gases" (ECV GHG) is the global distribution of important climate relevant ga
Droplet microfluidics has emerged as a promising platform for miniaturisation of biological assays on-chip. In droplet microfluidics small water droplets (nL-pL) surrounded by an immiscible carrier oil are generated at high throughput. In these droplets particles such as cells or microbeads can be encapsulated, and the idea is that each of these droplets can be used as small reaction chambers for
Concerns regarding environmental issues have led to increasing efforts for investigating sustainable production routes for the future industry that is based on renewable resources. Among the biobased chemicals, the C3-chemicals 3-hydroxypropionaldehyde (3-HPA), 1,3-propanediol (1,3-PDO) and 3-hydroxypropionic acid (3-HP), have been identified as top candidates for the chemical industry. Lactobacil
Context. Streaming instability is a key mechanism in planet formation, clustering pebbles into planetesimals with the help of self-gravity. It is triggered at a particular disk location where the local volume density of solids exceeds that of the gas. After their formation, planetesimals can grow into protoplanets by feeding from other planetesimals in the birth ring as well as by accreting inward
Changes in the latitudinal position and strength of the Southern Hemisphere westerlies (SHW) are thought to be tightly coupled to important climate processes, such as cross-equatorial heat fluxes, Atlantic Meridional Overturning Circulation (AMOC), the bipolar seesaw, Southern Ocean ventilation and atmospheric CO2 levels. However, many un
Most pathogens can infect a number of different host species, but host species often differ considerably in susceptibility to a given pathogen. In the case of zoonotic pathogens, natural hosts typically present little or no disease symptoms, while humans and other “spill-over” hosts often present severe symptoms. Differences in susceptibility do not only occur between natural and non-natural hosts
Objective: To describe the clinical and ultrasound characteristics of ovarian pure clear cell carcinoma. Methods: This was a retrospective study involving data from 11 ultrasound centers. From the International Ovarian Tumor Analysis (IOTA) database, 105 patients who had undergone preoperative ultrasound examination by an experienced ultrasound examiner between 1999 and 2016 were identified with a
Eddy covariance (EC) measurements are often used to validate net ecosystem productivity (NEP) estimated from satellite remote sensing data and biogeochemical models. However, EC measurements represent an integrated flux over their footprint area, which usually differs from respective model grids or remote sensing pixels. Quantifying the uncertainties of scale mismatch associated with gridded flux
Modern wind turbines are designed to withstand approximately for a lifetime of 20 years [1]. However, a very long design life of 100 years or more can be expected for high-quality concrete foundations. Thus there is a big difference in lifetime between wind turbines and foundations. There is a significant economic benefit of replacing the out-of-date wind turbine with a new turbine of better power
Nature-based solutions (NBS) focus on the material functioning of ecosystems as part of a transformative response to societal challenges. NBS represent a growing response to climate change with a range of interventions emerging across the world to address the causes and effects of climate change. The adoption of NBS is claimed to address a range of Sustainable Development Goals, including empowerm
Background: Family risks for urinary tract cancers (excluding kidney cancers) are known, but less is known about whether rare urinary tract cancer subtypes are also familial and if urinary tract cancers share familial risk for other (discordant) cancers. Objective: To investigate the impact of family history on urinary tract cancers (International Classification of Diseases version 7 code 181) and
The ability of intrahippocampal grafts of fetal septal-diagonal band tissue, rich in developing cholinergic neurons, to ameliorate cognitive impairments induced by bilateral fimbria-fornix transections in rats was examined in three experiments using the Morris water-maze to test different aspects of spatial memory. Experiment 1. Rats with fimbriafornix lesions received either septal cell suspensio
Importance: Nonsuicidal self-injury is prevalent in adolescence and associated with adverse clinical outcomes. Effective interventions that are brief, transportable, and scalable are lacking. Objective: To test the hypotheses that an internet-delivered emotion regulation individual therapy for adolescents delivered adjunctive to treatment as usual is superior to treatment as usual only in reducing
The reactivity of the phosphine-thioether ligands bis(2-diphenylphosphino) ethylthio)ethane (PSSP), bis(2-(diphenylphosphino) ethyl)sulfane (PSP), PPh2CH2CH2SMe (PS), PPh2(o-C6H4SMe (PortoS), and PPh(o-C6H4SMe)2 (PSS) towards low-valent carbonyl clusters has been studied. In all structurally characterized clusters, the ligand donor atoms are terminally coordinated. The phosphine-thioether ligands
Popular Abstract in Swedish Nästa år är det 400 år sedan Galileo Galilei för första gången riktade ett teleskop mot objekt på himlen. Allt sedan dess har teleskopet varit det viktigaste instrumentet för astronomins utveckling och med dess hjälp har vår kunskap om universum revolutionerats. Tack vare utvecklingen av teleskopet under dessa århundraden har allt ljussvagare objekt kunnat studeras, ochThis thesis presents the work on the design of, construction of, and finally observations with, an experimental setup comprising a small telescope equipped with adaptive optics. The facility has been assembled at Lund Observatory, where also observations on the sky have been made. The aim of this project was to gain hands-on knowledge in the development of a real adaptive optics system and eventua
Clothing evaporative resistance is one of the most important parameters for clothing comfort. The clothing evaporation resistance can be measured on a sweating guarded hotplate, a sweating thermal manikin or a human subject. The sweating thermal manikin gives the most accurate value on evaporative resistance of the whole garment ensemble compared to the other two methods. The determination of clot
Tubes fabricated from dilute Zr-alloys serve as miniature pressure vessels in Pressurized Heavy Water Reactors and are subjected to stress, aqueous corrosion and intense irradiation during service. Hydrogen evolved during the corrosion reaction may enter into the material and precipitate as hydride phase, which acquire platelet shaped morphology in Zr-alloys and are known to embrittle the host mat
The polynuclear compounds containing anisotropic metal ions often exhibit efficient barriers for blocking of magnetization at fairly arbitrary geometries. However, at variance with mononuclear complexes, which usually become single-molecule magnets (SMM) under the sole requirement of a highly axial crystal field at the metal ion, the factors influencing the SMM behavior in polynuclear complexes, e
Objective: The purpose of the study was to compare in prospective randomized fashion a manually sutured esophagogastric anastomosis in the neck and a stapled in the chest after esophageal resection and gastric tube reconstruction. Summary Background Data: Despite the fact that all reconstructions after esophagectomy will result in a cervical or a thoracic anastomosis, controversy still exists as t
