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-Reduced arterial compliance precedes changes in blood pressure, which may be mediated through alterations in vessel wall matrix composition. We investigated the effect of the collagen type I-alpha1 gene (COL1A1) +2046G>T polymorphism on arterial compliance in healthy individuals. We recruited 489 subjects (251 men and 238 women; mean age, 22.6+/-1.6 years). COL1A1 genotypes were determined using
The effect of strain and transforming growth factor beta on equine tendon fibroblasts (tenocytes) was assessed in vitro. Tenocytes were isolated from flexor and extensor tendons of horses from foetal to 10 years of age. These cells were cultured until confluent on collagen-coated silicone dishes. Cyclic biaxial strain of 9 +/- 1% was applied at 0.5 Hz for 24 hours with or without added TGFbeta1 or
Ligand induced activation of the beta-receptor for platelet-derived growth factor (PDGF) leads to activation of Src family tyrosine kinases. We have explored the possibility that the receptor itself is a substrate for Src. We show that Tyr934 in the kinase domain of the PDGF receptor is phosphorylated by Src. Cell lines expressing a beta-receptor mutant, in which Tyr934 was replaced with a phenyal
Particle formation events were analysed from aerosol number size distribution data collected at a background station in southern Sweden between February 2001 and May 2004. Events occurred on about 36% of all days and were favoured by high global radiation values. The clearest events (class I, 20% of all days) were observed when the formation rate of activated hypothetical clusters around 1 nm diam
The Sound Environment Centre at Lund University was established in March 2005. The centre is the first of its kind, both nationally and internationally. It is tasked with studying sound as a phenomenon, sound worlds and sound environments from a multi- and interdisciplinary perspective. It is a Lund University-wide body for education and research as well as external engagement in general for matte
Streptococcus bovis/Streptococcus equinus complex (SBSEC) is a common cause of infective endocarditis (IE). For IE-pathogens, the capacity to activate and aggregate platelets is believed to be an important virulence mechanism. While the interactions between bacteria and platelets have been described in detail for many Gram-positive pathogens, little research has been carried out with SBSEC in this
Environmental psychology conducts research, teaching and collaborations focused on the interaction between people and the environment from the perspective of the individual. The subject deals with how people experience their surroundings and are affected by them, as well as how humans affect the environment through their behaviour. The research encompasses the relationship to both the physical a
While the eddy covariance (EC) technique is a well-established method for measuring water fluxes (i.e., evaporation or 'evapotranspiration’, ET), the measurement is susceptible to many uncertainties. One such issue is the potential underestimation of ET when relative humidity (RH) is high (>70%), due to low-pass filtering with some EC systems. Yet, this underestimation for different types of EC sy
This article outlines an experimental and analytical expression study on the consequence of cement constituents, mix composition and curing conditions as regards self-desiccation in concrete. For this purpose nine concretes with three values of w/c (0.32, 0.38 and 0.50), based on two types of Portland Cement, were manufactured. Five per cent silica fume was used in one third of the concretes as ca
A new approach to analyze notched paper sheet loaded in mode I, based on cohesive crack modelling, is investigated. The method predicts final failure of the sheet, regardless of the sheet size and initial crack length. Onset of crack growth, stable crack growth and onset of unstable crack growth are predicted. The simulations of the notched paper sheet reveal that the concept of autonomy, i.e. ind
Introduction: Complicated perianal disease (cPD) may be the sole presentation of Crohn’s disease (CD). The role of small-bowel capsule endoscopy (SBCE) in the diagnostic algorithm of cPD is unclear. We aimed to evaluate the role of SBCE as a diagnostic tool, in patients with cPD, after a negative standard workup for CD. Methods: A multicenter, retrospective, cross-sectional study, in patients with
According to certain researchers, such as Meisel (2008), a child has a similar way of acquiring a second language (cL2 learners) as adults (aL2 learners) do after the age of four. However, the difference of age and cognitive maturation between an adult and a child awakes ones curiousness of investigating how much the linguistic development of a cL2 learner resembles the one of aL2 learners. This s
Institutionen för arkeologi och antikens historia bedriver forskning och utbildning inom fyra ämnen – antikens kultur och samhällsliv, arkeologi, historisk arkeologi och historisk osteologi. Institutionen har funnits i olika former vid Lunds universitet sedan 1805 men fick sin nuvarande sammansättning 2001. Sedan 2016 rymmer institutionen även Laboratoriet för digital arkeologi (DARKLab), en infraThe Department of Archaeology and Ancient History conducts research and education in four subjects – Classical Archaeology and Ancient History, Archaeology, Historical Archaeology and Historical Osteology. The department has existed in various forms at Lund University since 1805 but was given its current composition in 2001. Since 2016, the department also houses the Laboratory for Digital Archaeo
Direkt Profil est un analyseur automatique de textes écrits en français comme langue étrangère. Utilisant des techniques du Traitement Automatique des Langues (TAL), son but est de produire une évaluation du stade de développement des apprenants sous la forme d’un profil grammatical. Direkt Profil réalise une analyse des phrases fondée sur des itinéraires d’acquisition, i.e. des phénomènes morphos
