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Chromosome dynamics and genomic instablity in neuroblastoma. Three genomic pillars: MYCN amplification, numerical and structural changes.

Popular Abstract in Swedish Neuroblastom är den vanligaste solida tumören, utanför hjärnan, hos små barn och finns nästan inte alls hos vuxna. Varje år insjuknar mellan femton och tjugo barn i Sverige, de flesta före två års ålder. Överlevnaden har ökat de senaste tjugo åren men är fortfarande på låga nivåer för de mer aggressiva formerna. Neuroblastom uppstår i det sympatiska nervsystemet. DärförIn this thesis, the main focus has been on the childhood cancer neuroblastoma, one of the most common and lethal childhood tumours. Neuroblastoma has througout the years continued to be a clinical and biological enigma. Our first focus was on one of the most important biological risk factors in neuroblastoma -- amplification of the oncogene MYCN in the tumour cells. Because amplified MYCN typical

Reading a glycocode - mechanism and function of galectin-glycan interactions

There is an intensive interest in characterising the structure and function of galectins, which is not surprising given their many important cellular functions and strong implications in human disease. Understanding the mechanisms involved in galectin functions will help to find selective and novel strategies for disease treatment and diagnosis. A key to this lies in their carbohydrate binding spe

Cost-effectiveness of surgery and its policy implications for global health: a systematic review and analysis

Background The perception of surgery as expensive and complex might be a barrier to its widespread acceptance in global health efforts. We did a systematic review and analysis of cost-effectiveness studies that assess surgical interventions in low-income and middle-income countries to help quantify the potential value of surgery. Methods We searched Medline for all relevant articles published betw

Accuracy of patient-specific I-131 dosimetry using hybrid whole-body planar-SPECT/CT I-123 and I-131 imaging

Purpose: This study aimed to assess the accuracy of patient-specific absorbed dose calculations for tumours and organs at risk in radiopharmaceutical therapy planning, utilizing hybrid planar-SPECT/CT imaging. Methods: Three Monte Carlo (MC) simulated digital patient phantoms were created, with time-activity data for mIBG labelled to I-123 (LEHR and ME collimators) and I-131 (HE collimator). The s

Uncertainty, Worth, Identity : How Early Career Academics Navigate Evaluative Landscapes

This dissertation explores the interplay between valuation and academic socialization, addressing the question: how do early career academics navigate evaluative landscapes? Having completed their doctoral education but yet to find stable employment, early career academics are generally viewed as the most vulnerable group of academic staff. Comparing how individuals within this group seek to demonThis dissertation explores the interplay between valuation and academic socialization, addressing the question: how do early career academics navigate evaluative landscapes? Having completed their doctoral education but yet to find stable employment, early career academics are generally viewed as the most vulnerable group of academic staff. Comparing how individuals within this group seek to demon

A simple clinical assessment is superior to systematic triage in prediction of mortality in the emergency department

Objective To compare the Danish Emergency Process Triage (DEPT) with a quick clinical assessment (Eyeball triage) as predictors of short-term mortality in patients in the emergency department (ED).Methods The investigation was designed as a prospective cohort study conducted at North Zealand University Hospital. All patient visits to the ED from September 2013 to December 2013 except minor injurie

Prognosis of Intracerebral Hemorrhage Related to Antithrombotic Use : An Observational Study From the Swedish Stroke Register (Riksstroke)

BACKGROUND AND PURPOSE: To date, large studies comparing mortality and functional outcome of intracerebral hemorrhage (ICH) during oral anticoagulant (OAC), antiplatelet, and nonantithrombotic use are few and show discrepant results. METHODS: We used data on 13 291 patients with ICH registered in Riksstroke between 2012 and 2016 to compare 90-day mortality and functional outcome following OAC-rela

Does Collaboration between General Practitioners and Pharmacists Improve Risk Factors for Cardiovascular Disease and Diabetes? A Systematic Review and Meta-Analysis

Objective: To assess whether inter-professional, bidirectional collaboration between general practitioners (GPs) and pharmacists has an impact on improving cardiovascular risk outcomes among patients in the primary care setting. It also aimed to understand the different types of collaborative care models used. Study design: Systematic review and Hartung-Knapp-Sidik-Jonkman random effects meta-anal

Structure and energetics of molecular recognition in galectin-3-ligand interactions

Molecular recognition is the key aspect of any cellular and biological function. Two or more molecules interacting with each other cause the effects that drives various basic functions that are fundamental to cells. Be these protein-protein, protein-nucleic acid or protein-ligand interactions, they all play important roles in a cell. Protein-ligand interactions are the most studied as they can havMolecular recognition is the key aspect of any cellular and biological function. Two or more molecules interacting with each other cause the effects that drives various basic functions that are fundamental to cells. Be these protein-protein, protein-nucleic acid or protein-ligand interactions, they all play important roles in a cell. Protein-ligand interactions are the most studied as they can hav

Copeptin as a predictive marker of incident heart failure

AIMS: Heart failure (HF) is a common disease with increasing prevalence and poor prognosis. The vasopressin (VP) marker copeptin predicts development of diabetes mellitus, diabetic heart disease, coronary artery disease, and premature mortality. Copeptin is elevated in HF patients and predicts a worse outcome. This study aims to investigate whether copeptin can predict HF development.METHODS: Cope

Soft computing assessment of current and future groundwater resources under CMIP6 scenarios in northwestern Iran

Excessive use of water resources in combination with climate change threaten to significantly reduce groundwater in arid and semiarid regions. We studied the effects of climate change on the groundwater level for the important Dehgolan Aquifer in northwestern Iran. The water level in this aquifer has dropped by about 35 m during the last 30 years. Soft computing techniques were used together with

Progressionsplan Naturvetenskaplig Masterexamen Huvudområde Molekylärbiologi Rev 230525-

Bilaga 2: progressionsplan Sida 1 av 31 Bilaga 2 Progressionsplan för naturvetenskaplig masterexamen, huvudområde Molekylärbiologi Biologiska institutionen Progressionsplan för naturvetenskaplig masterexamen, huvudområde molekylärbiologi En generell examen ska uppfylla de nationella examensmålen och ha en successiv, poängangiven fördjupning inom huvudområdet, inklusive ett examensarbete. I denna p

https://www.naturvetenskap.lu.se/internt/sites/naturvetenskap.lu.se.internt/files/2023-12/Progressionsplan%20naturvetenskaplig%20masterexamen%20huvudomra%CC%8Ade%20molekyla%CC%88rbiologi%20rev%20230525-.pdf - 2026-05-28

Allman-studieplan-klinisk-medicin-2018-01-01

Postadress Box 117, 221 00 LUND Telefon växel 046-222 00 00 Telefax 046-222 41 70 E-post info@med.lu.se Internet http://www.med.lu.se Medicinska fakultetsstyrelsen Allmän studieplan för utbildning på forskarnivå i klinisk medicin (Fastställd av Medicinska fakultetsstyrelsen 2007-05-24) Studieplanen träder ikraft den 1 juli 2007. Reviderad av Forskarutbildningskommittén den 25 mars, 2010 Gäller frå

https://www.intramed.lu.se/sites/intramed.lu.se/files/2022-12/allman-studieplan-klinisk-medicin-2018-01-01.pdf - 2026-05-28

Podd: Digitala påhopp plågar lärare – Vetenskap och Hälsa

Podd: Digitala påhopp plågar lärare – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Podd: Digitala påhopp plågar lärare 2024-05-03 Vetenskap & hälsa · Digitala påhopp plågar lärare   Aggressiva mejl från föräldrar, grupper på sociala medier som spårar ur och där enskilda lärare hängs ut me

https://www.vetenskaphalsa.se/podd-digitala-pahopp/ - 2026-05-28

Från bläckfria gravyrer till lätta lastpallar när studenter visade sina förpackningsprototyper

Från bläckfria gravyrer till lätta lastpallar när studenter visade sina förpackningsprototyper Hoppa till huvudinnehåll Den här webbplatsen använder cookies för att förbättra användarupplevelsen. Genom att fortsätta använda webbplatsen samtycker du till att cookies används enligt vår cookie-policy (på LTH:s webbplats) . Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska

https://www.design.lth.se/article/fraan-blaeckfria-gravyrer-till-laetta-lastpallar-naer-studenter-visade-sina-foerpackningsprototyper/ - 2026-04-20

Medicinska genombrott – forskning som betytt mycket för många – Vetenskap och Hälsa

Medicinska genombrott – forskning som betytt mycket för många – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Medicinska genombrott – forskning som betytt mycket för många 2018-10-15 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Forskningsresultat som över

https://www.vetenskaphalsa.se/medicinska-genombrott-forskning-som-betytt-mycket-for-manga/ - 2026-05-26

Specialdesignat protein slår mot flera olika bakterier – Vetenskap och Hälsa

Specialdesignat protein slår mot flera olika bakterier – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Specialdesignat protein slår mot flera olika bakterier 2017-12-14 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Foto: Bill Branson, Wikimedia Commons I t

https://www.vetenskaphalsa.se/specialdesignat-protein-slar-mot-flera-olika-bakterier/ - 2026-05-26

Exam and degree

- Performance Programmes in Music As stated in the Higher Education Ordinance, the degree project is mandatory for graduating:For artistic [bachelor/master] degree the student shall, within the frame of the course requirements, have fulfilled an independent work (degree project) of at least 15 academic credits within the main area of the programme (SFS, 1993:100).Your artistry as an instrumentalis

https://www.mhm.lu.se/internt/current-student/exam-and-degree - 2026-05-27