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Waterbird phenology and opportunistic acceptance of a low quality staging site at Lake Baikal, eastern Siberia
Crystal structure of β-glucosidase 1A from Thermotoga neapolitana and comparison of active site mutants for hydrolysis of flavonoid glucosides
The β-glucosidase TnBgl1A catalyses hydrolysis of O-linked terminal β-glycosidic bonds at the nonreducing end of glycosides/oligosaccharides. Enzymes with this specificity have potential in lignocellulose conversion (degrading cellobiose to glucose) and conversion of bioactive flavonoids (modification of glycosylation results in modulation of bioavailability). Previous work has shown TnBgl1A to hy
Site-selective 13C labeling of proteins using erythrose
Electron paramagnetic resonance spectroscopy of site-directed spin labels reveals the structural heterogeneity in the N-terminal domain of apoA-I in solution
Apolipoprotein A-I (apoA-I) is the major protein constituent of high density lipoprotein (HDL) and plays a central role in phospholipid and cholesterol metabolism. This 243-residue long protein is remarkably flexible and assumes numerous lipid-dependent conformations. Consequently, definitive structural determination of lipid-free apoA-I in solution has been difficult. Using electron paramagnetic
Prevalence of avian haemosporidian parasites is positively related to the abundance of host species at multiple sites within a region
Site-specific photocoupling of pBpa mutated scFv antibodies for use in affinity proteomics
Fibromodulin Interacts with Collagen Cross-linking Sites and Activates Lysyl Oxidase.
The hallmark of fibrotic disorders is a highly cross-linked and dense collagen matrix, a property driven by the oxidative action of lysyl oxidase. Other fibrosis-associated proteins also contribute to the final collagen matrix properties, one of which is fibromodulin - its interactions with collagen affect collagen cross-linking, packing, and fibril diameter. We investigated the possibility that a
Incorporation of Multinuclear Copper Active Sites into Nitrogen-Doped Graphene for Electrochemical Oxygen Reduction
Java wildcards meet definition-site variance
Chemical Understanding of the Limited Site-Specificity in Molecular Inner-Shell Photofragmentation
Effect of the electrochemical active site on thermal stress in solid oxide fuel cells
The M17 leucine aminopeptidase of the malaria parasite Plasmodium falciparum : importance of active site metal ions in the binding of substrates and inhibitors
The M17 leucine aminopeptidase of the intraerythrocytic stages of the malaria parasite Plasmodium falciparum (PfLAP) plays a role in releasing amino acids from host hemoglobin that are used for parasite protein synthesis, growth, and development. This enzyme represents a target at which new antimalarials could be designed since metalloaminopeptidase inhibitors prevent the growth of the parasites i
