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Efterfrågan inom hälso- och sjukvården ökar på grund av en växande population med allt fler äldre och kroniskt sjuka personer. Dessutom förväntar sig dagens patienter en lättillgänglig vård. För att möta den tilltagande efterfrågan spelar digitalisering en viktig roll. För att digitaliseringen ska lyckas är en god integrationen mellan nya digitala verktyg och befintliga system av stor betydelse. DThe demand in health care is increasing due to a growing population with more elderly and chronically ill people. In addition, the patients expect easy access to health care. To be able to meet the growing demand in the health care, digitization plays an essential role. For the digitization to be successful, a good integration of new digital tools in existing systems is of great importance. Also,

Popular Abstract in Swedish Populärvetenskaplig sammanfattning Felaktig DNA-reparation av typen mismatch repair (MMR) uppkommer i 15-17% av cancer i tjock- och ändtarm (kolorektalcancer). MMR defekter är av betydelse i tre situationer: • MMR defekta tumörer har en bättre prognos än övrig tjock- och ändtarmscancer, vilket kan användas för att avgöra huruvida en patient skall erbjudas sk. adjuvant Mismatch repair (MMR) deficiency is carcinogenic and can either have somatic/sporadic causes (i.e. epigenetic silencing or somatic inactivation) or hereditary causes (Lynch syndrome due to a germline mutation in one of the MMR genes ¬- MLH1, MSH2, MSH6, PMS2). The identification of MMR defective colon cancer is clinically relevant for diagnostic, prognostic and potentially also for treatment-predi

Recent reports suggested frequent occurrence of cancer associated somatic mutations within regulatory elements of the genome. Based on initial exome sequencing of 21 melanomas, we report frequent somatic mutations in skin cancers in a bidirectional promoter of diphthamide biosynthesis 3 (DPH3) and oxidoreductase NAD-binding domain containing 1 (OXNAD1) genes. The UV-signature mutations occurred at

The E-GIS project partnership comprised 10 partners (universities, organisations and private bodies) from 6 European countries; Bulgaria, Lithuania, The Netherlands, Norway, Portugal and Sweden. The E-GIS project was initiated in order to: • Establish competent nettworks between universities and private bodies for cooperation on an European level within the GIS area – both for this project and fo

The neutron beam at the Studsvik facility for boron neutron capture therapy (BNCT) and the validation of the related computational model developed for the MCNP-4B Monte Carlo code are presented. Several measurements performed at the epithermal neutron port used for clinical trials have been made in order to validate the Monte Carlo computational model. The good general agreement between the MCNP c

Aims and objectives. The aim was to compare faecal incontinence and related bowel symptoms among men and women and being dependent or not (aged ≥75 years) and furthermore to identify which bowel symptoms predicted help seeking, dependency and low quality of life (QoL). Background. Faecal incontinence (FI) in old age is a common condition and influences daily life to a great extent, although few a

Our purpose was to examine why and how to start a ”bridge building enterprise” between qualified Chinese human capital and Swedish structure capital. The theoretical framework consists of literature from well renowned authors and is divided into four different parts: Intellectual Capital, Knowledge Management, China & Intercultural understanding. The empirical foundation has been gathered from

The purpose of this analytical authoethnography is to share my experiential and theoretical reflexions on how entrepreneurs keep a positive attitude and learning approach during the entrepreneurial process, specially when facing failures. First, I will analyze some theories related to entrepreneurial learning and recovery processes. The analysis is made in the light of my own experiences, which di

The signing of the North Atlantic Treaty on the 4th of April 1949 became a watershed for the Nordic states and divided the normally very homogenous groupinto two separate camps. By examining this phenomenon from three different methodological approaches, this thesis aims to explain why the division occurred. The methodological approaches are sectioned into macro meso and micro levels in order to d

We have compiled data on the occurrence of a threatened beetle, Osmoderma eremita, in Sweden. The species inhabits tree hollows with wood mould. The data were compiled from field surveys conducted in 1993-2003, using pitfall traps at 401 localities and using wood mould sampling at 104 localities. We have also gone through published data and all larger Swedish museums and registered old records. O.

Dark matter accounts for about 85% of all matter in the Universe, yet its particle nature remains unknown. The Light Dark Matter eXperiment (LDMX) is a proposed fixed-target missing-momentum experiment that intends to probe the predominantly experimentally uncharted MeV-GeV mass range for "light dark matter". A significant challenge for LDMX is to efficiently veto rare photo-nuclear back

Infantile colic is common, but no safe and effective conventional treatment exists. The use of acupuncture has increased despite weak evidence. This practitioner survey explores and discusses how infantile colic is regarded and treated in Traditional Chinese Medicine (TCM). The study is based on personal communication with 24 acupuncturists from nine countries. These acupuncturists specialize in p

Objective: The aim of this study was to increase the understanding of stroke survivors' thoughts and experiences from returning to work after stroke. Methods: Semi-structured interviews were carried out with twelve persons, based on a thematic interview guide. A qualitative content analyse were performed. Results: The main theme; was Striving for optimal function at work creates mixed feelings of

Populärvetenskaplig sammanfattning: Solen värmer jordytan olika mycket på olika platser dels beroende på om ytan är land, hav eller is och dels beroende på den breddgrad ytan är belägen på. Denna ojämna uppvärmning ger upphov till regionala ojämnheter i lufttrycket. Det är dessa tryckojämnheter som styr vindriktningarna i atmosfären och därmed vart alla vädersystemen rör sig. Det är alltså den ojäLong time-series of pressure measurements often have high quality because the early instruments are more or less the same as the modern ones. A time-series from Lund consisting of three daily measurements from 1780-1997 has been homogenised and is therefore suitable for analysing possible influences of the enhanced greenhouse effect. According to a two-layer model of the atmosphere one finds a shi

After the fall of communism in Yugoslavia the ethnic resentment grew stronger and escalated in to interethnic civil conflict in 1992. After international intervention the General Framework Agreement for Peace (GFAP) installed peace in 1995. The treaty's aim was not only to establish peace but also to institute democracy in Bosnia. The OSCE were given the task to implement democracy within poli

Public procurement - which can shortly be explained with the government's activity of purchasing goods and services - presents one of the largest economic markets in the world, accounting, on average, for 15 per cent of the gross national product (GDP) worldwide. One of the most controversially debated issues regarding public procurement is that of procurement linkages. The questions evolve ar

This thesis examines which factors (gender, age, level of education, and prior experience of therapy) that impact attitudes towards seeking therapy in Sweden, and if any significant main effects and interaction effects are present. Further, the thesis also aims to examine which variable, perceived public stigma or self-stigma, is the best to predict attitudes toward seeking therapy. The study was

Syftet med vår studie är att undersöka hur fyra sångpedagoger beskriver hur de förhåller sig till och arbetar med personligt uttryck, härmning och förebildning samt genrekunskap och hur deras syn påverkar samverkan mellan begreppen och metoderna. Studien är av kvalitativ art och vi har använt oss av semistrukturerade frågor för att fånga pedagogernas tankar och åsikter. Sångpedagogerna säger sigThe purpose of our study is to investigate how vocal teachers describe how they relate to and work with personal expression, imitation, demonstration, knowledge about genre and how their views affect the interaction between these concepts and methods. The study is qualitative in nature and we have used semi-structured questions to capture the teachers’ thoughts and opinions. The vocal teachers s

Bearing a child and giving birth are often considered as a life-changing event in the life of a woman and her family, a source of joy and fulfillment. But in spite of the progress achieved in the last century, every two minutes one woman still dies from pregnancy or childbirth related causes (WHO 2018). All too often, becoming a mother can be associated with pain, suffering and even distress, disa

Background: Previous studies have focused on weight maintenance following weight loss, i.e. secondary weight maintenance (SWM). The long-term results of SWM have been rather modest and it has been suggested that preventing initial weight gain, i.e. primary weight maintenance (PWM), may be more successful. Therefore, developing a prevention strategy focused on PWM, enabling normal weight or overwei