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Chromosome abnormalities, in particular translocations, and gene fusions are hallmarks of neoplasia. Although both have been recognized as important drivers of cancer for decades, our knowledge of the characterizing features of the cytobands involved in recombinations is poorly understood. The present study, based on a comparative analysis of 10 442 translocation breakpoints and 30 762 gene fusion
Background: Cystic fibrosis (CF) is most common in populations of Northern European ancestry where the F508del variant predominates. In 2020, Iceland became a member of the European Cystic Fibrosis Society Patient Registry, and we launched an epidemiological study of CF in Iceland. The study aimed to determine the prevalence and the genetic variants present in the country. Furthermore, we aimed to
Background: Involving service users in inpatient care and recovery planning has gained interest worldwide. Our purpose was to evaluate the process of implementation of a coproduced Recovery Guide (RG) intervention in 22 inpatient wards in Sweden, in terms of context, implementation process and mechanisms of impact over 12 months.Methods: A mixed method design and a process evaluation framework wer
This meta-analysis aims to evaluate the long-term survival and prognostic factors in patients with metastatic small intestine neuroendocrine tumors (siNETs). Patients with siNETs usually present with advanced disease, limiting curative treatment options. The overall survival seems favorable compared to other cancers, but differences in terminology, lack of consistent coding, conflicting results fr
In 2015, LIBER commissioned the “Working group on Research and Education”. The goal was to collect best practices in library support to both education and research, in part by examining user survey data. As a first step the group started a European LibQUAL consortium, which was evaluated in 2016. As a second step, a survey sent to all 301 European LIBER university libraries asking questions pertai
The removal of natural organic matter (NOM) from boreal lake water by a novel capillary nanofiltration (NF) membrane was predicted using a computational fluid dynamics (CFD) modelling approach. The 2-dimensional axis-symmetric model was based on a 48 m3/day NF pilot plant operating in cross-flow mode on water containing 8 mg/L total organic carbon (TOC) at fluxes ranging from 10 to 25 L/m2/h and v
We analyze the oxygen abundances of a stellar sample representative of the two major Galactic populations: the thin and thick disks. The aim is to investigate the differences between members of the Galactic disks and contribute to the understanding of the origin of oxygen chemical enrichment in the Galaxy. The analysis is based on the [O i] = 6300.30 Å oxygen line in high-resolution spectra (R ∼ 5
This chapter points to the fact that notwithstanding the global spread of English-medium instruction (EMI) and a growing body of research into EMI in different disciplines and higher education contexts, transnational, and comparative studies on EMI that draw on large-scale cross-institutional data are extremely scarce. Hence, the TAEC Corpus was created as part of the Erasmus+ project "Transnation
Jaktturism anses ofta spela en viktig roll i hållbar landsbygdsutveckling. Turismenkan skapa arbeten, samt bidra till att traditioner och miljöer bevaras. En kommersiell jakt som riktar sig till lokala såväl som inresande jägare kan innebära att viltet kan användas som resurs på flera och nya sätt. När jakten ramas in och paketeras som turismprodukt, där boende, måltider och guidning ingår, kan ja
INTRODUCTION: This article draws on understandings from reproductive justice, crip and queer theories to discuss gonadectomy for children and young people with gonadal variations. Gonadectomy is sometimes performed on people with gonadal variations without their free and informed consent. Some parents report experiencing pressure to consent to such surgery when their children are young. We understINTRODUCTION: This article draws on understandings from reproductive justice, crip and queer theories to discuss gonadectomy for children and young people with gonadal variations. Gonadectomy is sometimes performed on people with gonadal variations without their free and informed consent. Some parents report experiencing pressure to consent to such surgery when their children are young. We underst
In recent years there has been much attention paid to corporate scandals, and in the Swedish media the Skandia incidents have become a serial as, years after the incidents was revealed, sentences are passed on those involved in the scandal. The former president and vice president of the joint-stock company Skandia were both prosecuted for the economic crime gross breach of faith committed by an ag
The aim of this study was to examine how social workers within the social services in Sweden worked with and defined the child rights principle “the Best Interests of the Child”, which derives from Article 3 of the UN Convention on the “Rights of the Child”. The study is limited to only examining social workers that have been working with children of parents with substance abuse issues. More speci
To feel self-evident – The Licensing of Hospital Based Social Workers As of July 1 2019 hospital based social workers can apply for a license - similar to that of doctors and psychologists - which also means that their job title is protected. The aim of this study was to explore how hospital based social workers within the children and adolescent psychiatric department related to the fact that
Ecosystem services have been widely discussed as of late, and more so than ever, has the topic of resilience and sustainable city planning taken an important role in the debate over how we can meet the present challenges concerning livable cities. The costs and the benefits of urban trees is an important factor in sustainable city planning and their consideration early in the planning stages canno
Abstract This project delves into the interplay of physical interfaces of electronic devices and the creative act of making music. Through a literature review, it was understood that there are key UI & UX principles which need to be followed in the development of user-friendly products of this type. In-depth interviews revealed that users find sub-menus challenging, desire a reduction in scre
Around the 150th anniversary in 1998, historical research showed new interest for the wave of revolutions that swept across Europe in 1848. This research focused on providing a new European frame of interpretation for the events in 1848, questioning the exclusive national historiographical traditions of European history, a field of study already formed by the works of Jean-Baptiste Duroselle in 19
Stockholm har under de senaste åren visat stora hyresökningar på kontorsmarknaden samtidigt som bostadsmarknaden har avsvalnat. Även fast Sverige placeras bra i avseende på flera mått såsom vakans och BNP har städer som också haft bra tillväxt i BNP och låg vakans inte uppvisat lika hög hyrestillväxt. Den här studien undersöker fallet om bostadsmarknaden har påverkat kontorshyrorna i Stockholm. OmIn recent years, Stockholm has shown a large rent increases in the office market simultaneously as the housing market has cooled off. Although Sweden is well measured in several areas such as vacancy and GDP, other cities that also produced significant GDP growth and low vacancy rates have not shown as much rental growth as Stockholm. This study examines if and how the housing market has affected
This study examines how section managers within social services describe their scope of action and preventive work in relation to stress and exhaustion among social workers. Work-related exhaustion is a major cause of sick leave in Sweden, and social services constitute a particularly high-risk context due to heavy workloads, emotional demands, and organizational constraints. Using a qualitative r
This study aimed to create an understanding of how children within Jehovah’s Witnesses have gotten their emotional needs met during their childhood. We also wanted to study if there was a correlation between men and women and the attitude of needing emotional support. The empirical data has been collected with a survey we sent out within a closed group of non-active members. 33 respondents answere
