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30-day postoperative mortality and the effects of hospital preparedness during the COVID-19 pandemic: a pooled analysis of prospective international cohort studies

BackgroundSurgical services were poorly prepared for the COVID-19 pandemic, leading to widescale disruption to elective activity. This study aimed to identify actionable priorities to strengthen pandemic preparedness of surgical and hospital systems.MethodsThis study pooled data from three international, prospective cohort studies including patients who had a positive SARS-CoV-2 test result in the

Perioperative trajectories of acute-phase proteins and their association with major postoperative complications in advanced ovarian cancer

BackgroundAcute-phase proteins (APPs) reflect systemic inflammation and nutritional status, yet their perioperative trajectories and clinical utility as biomarkers of outcome in advanced ovarian cancer (aEOC) remain unclear. We aimed to characterise perioperative APP fluctuations and assess their associations with postoperative complications.MethodsThis observational study included patients underg

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1(3) Saco-S-rådet PROTOKOLL Linköpings universitet fört vid styrelsemöte 2025-09-17 Styrelsen Närvarande: Peter Hult, IMT Kjell Karlsson, ITN Torbjörn Larsson, MAI Janerik Lundquist, IEI Åsa Rybo Landelius, IFM David Rule, MAI Carina Wennerholm, HMV Therese Winder, UF Per Gyberg, TEMA, suppleant Maria Hedtjärn, UF, suppleant Tove Mattsson, IBL, suppleant Darcy Parks, TEMA, adjungerad Frånvarande:

https://www.saco.se/globalassets/lokala-akademikerforeningar/statlig/linkopings-universitet-liu/dokument/protokoll/protokoll20250917-signed.pdf - 2026-04-26

Parametric Analysis of the Effect of Pilot Quantity, Combustion Phasing and EGR on Efficiencies of a Gasoline PPC Light-Duty Engine

In this paper, a parametric analysis on the main engine calibration parameters applied on gasoline Partially Premixed Combustion (PPC) is performed. Theoretically, the PPC concept permits to improve both the engine efficiencies and the NOx-soot trade-off simultaneously compared to the conventional diesel combustion. This work is based on the design of experiments (DoE), statistical approach, and i

Gestational age-related reference values for Apgar score and umbilical cord arterial and venous pH in preterm and term newborns

INTRODUCTION: Despite much literature on reference values of acid-base status in umbilical cord blood at birth, there are as yet no studies performed to determine gestational age-dependent references in cord venous blood and no studies on preterm acid-base standards. Similarly, the normal reference range of Apgar scores for term and preterm infants has not yet been determined.MATERIAL AND METHODS:

Evaluation of a method for isocapnic hyperventilation : a clinical pilot trial

Background: Isocapnic hyperventilation (IHV) is a method that shortens time to extubation after inhalation anaesthesia using hyperventilation (HV) without lowering airway CO 2 . In a clinical trial on patients undergoing long-duration sevoflurane anaesthesia for major ear–nose–throat (ENT) surgery, we evaluated the utility of a technique for CO 2 delivery (DCO 2 ) to the inspiratory limb of a clo

Comparison of different views with three-dimensional echocardiography: apical views offer superior visualization compared with parasternal and subcostal views.

Studies seeking to validate real-time three-dimensional echocardiography (3DE) with regard to cardiac function and dimensions have almost exclusively used apical views. However, it has never been examined whether apical views are preferable to parasternal or subcostal views. In the present study, we compared the feasibility of 3DE volumetric measurements of the four heart chambers in three differe

Delade åsikter om dödshjälp bland palliativ vårdpersonal

Läkartidningen 5-6/2025. Egenreferat. Dödshjälp, det vill säga eutanasi och läkarassisterat självmord, är olaglig i Sverige, men debatten om legalisering är fortsatt aktuell.Läkarförbundet genomförde 2021 en enkätundersökning om läkarkårens inställning till dödshjälp. 41 procent av de svarande ansåg att dödshjälp bör tillåtas enligt svensk lag (medan 34 procent motsatte sig detta), men endast 29 p

Health-related quality of life and supportive care needs in young adult cancer survivors—a longitudinal population-based study

Purpose: To examine health-related quality of life (HRQoL) and supportive care needs among young adult (YA) cancer survivors up to 3 years post-diagnosis. Methods: A national cohort of individuals diagnosed at 18–39 years with breast, cervical, ovarian, or testicular cancer, lymphoma or brain tumor was approached with surveys at 1.5 (n = 1010, response rate 67%) and 3 (n = 722) years post-diagnosi

Shrinking and financial development in Kenya and Tanzania, 1960-2020

The failure of many countries in the Global South to catch up economically to the advanced economies of the Global North has long been a topic of interest to economic historians and development economists. Traditionally, researchers focused their attention on the question of growth –how can a country achieve growth to catch up? In recent years, however, a new research programme has begun to shift

Investigation of oxidation mechanisms in magnesium by density functional theory

Magnesium (Mg) is a metallic material with a great range of potential applications. It can be used as the lightest structure material in automotive and aviation sectors, medical implants, hydrogen storge, etc. In such applications, oxidation and corrosion reactions play a critical role in the effectiveness of use. Therefore, deeper understanding of the fundamental mechanisms of oxidation and corro

Initial pathology in aggressive pituitary tumours and carcinomas : 2b or not 2b?-that is the question

From a cohort of 171 patients comprising 121 aggressive pituitary tumours (APT) and 50 pituitary carcinomas (PC), the clinicopathological or five-tiered classification based on tumour invasion and proliferation evaluated by at least 2 proliferative markers over the cut-offs (Ki-67 ≥3% or ≥10%, p53 positive or expressed in %, mitotic count >2%), could be applied on 43 tumours: 20 PC and 23 APT. At

Excess Mortality and Loss of Life Expectancy After Myocardial Infarction : A Registry-Based Matched Cohort Study

BACKGROUND: The effect of myocardial infarction (MI) on life expectancy is difficult to study because the prevalence of MI hinders direct comparison with the life expectancy of the general population. We sought to assess this in relation to age, sex, and left ventricular ejection fraction (LVEF) by comparing individuals with MI with matched comparators without previous MI. METHODS: We included pat

Elderly care recipients in a swedish municipality living in their own homes and being cared for by their families; their diseases, functional health status and care provided as reported by formal carers.

The aim of this study was to investigate from the perspective of formal carers the care given to people aged 65 and over, who are cared for in their own homes by informal care. Thirty-three district nurses (DNs) and 20 home service assistants in a municipality with 13500 inhabitants (over 65 years old), were interviewed about the location of care recipients and 398 care recipients were located. Mo

Mannen i ledet. Takt och otakt i värnpliktens skugga

Popular Abstract in Swedish Från början användes uttrycket "mannen i ledet" bara om meniga soldater, men det är också ett bildligt uttryck med innebörden gemene man, gräsrot, medlem på fältet/gräsrotsnivå/verkstadsgolvet. Den här avhandlingen handlar om unga män som under mitten av 1990-talet gjorde lumpen på ett pjäskompani vid Wendes artilleriregemente i skånska Hässleholm. ”Pjäs” betyder kanoneThis dissertation deals with young men who in the mid 1990s made their military service at a cannon company at Wende’s artillery regiment in the scanian town Hässleholm. ”Cannon” refers not only to cannons, but also to haubitses, grenade-throwers and other heavy arms. The focus, however, is on cultural and social aspects of everyday military service. What does actually happen in the encounter betw

Inter-observer agreement in describing the ultrasound appearance of adnexal masses and in calculating the risk of malignancy using logistic regression models.

Purpose: To estimate inter-observer agreement with regard to describing adnexal masses using the International Ovarian Tumor Analysis (IOTA) terminology and the risk of malignancy calculated using IOTA logistic regression models LR1 and LR2, and to elucidate what explained the largest inter-observer differences in calculated risk of malignancy. Experimental Design: 117 women with adnexal masses we

Assessment of primary hip osteoarthritis: comparison of radiographic methods using colon radiographs : comparison of radiographic methods using colon radiographs

OBJECTIVE: To compare the reliability of quantitative measurement of minimum hip joint space with a qualitative global assessment of radiological features for estimating the prevalence of primary osteoarthritis (OA) of the hip in colon radiographs.METHODS: All colon radiographs from patients aged 35 or older, taken at three different radiographic departments in Iceland during the years 1990-96, we

First stars V - Abundance patterns from C to Zn and supernova yields in the early Galaxy

In the framework of the ESO Large Programme ``First Stars'', veryhigh-quality spectra of some 70 very metal-poor dwarfs and giants wereobtained with the ESO VLT and UVES spectrograph. These stars are likelyto have descended from the first generation(s) of stars formed after theBig Bang, and their detailed composition provides constraints on issuessuch as the nature of the first supernovae, the eff

Overexpression of the Ca2+-binding protein calreticulin in the endoplasmic reticulum improves growth of tobacco cell suspensions (Nicotiana tabacum) in high-Ca2+ medium

Calreticulin (CRT) is a eukaryotic, highly conserved, Ca2+-binding protein predominantly located in the endoplasmic reticulum (ER) lumen. In addition to being involved in the regulation of cellular Ca2+, calreticulin is a key quality control element during protein folding in the ER lumen. Tobacco (Nicotiana tabacum L.) suspension cells overexpressing a maize CRT (CRT1a) were used here to examine t

Spatial and temporal dynamics in eddy covariance observations of methane fluxes at a tundra site in northeastern Siberia

In the past two decades, the eddy covariance technique has been used for an increasing number of methane flux studies at an ecosystem scale. Previously, most of these studies used a closed path setup with a tunable diode laser spectrometer (TDL). Although this method worked well, the TDL has to be calibrated regularly and cooled with liquid nitrogen or a cryogenic system, which limits its use in r