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OBJECTIVES: To investigate associations between a high genetic disease risk and disease severity in patients with systemic lupus erythematosus (SLE).METHODS: Patients with SLE (n=1001, discovery cohort and n=5524, replication cohort) and healthy controls (n=2802 and n=9859) were genotyped using a 200K Immunochip single nucleotide polymorphism array. A genetic risk score (GRS) was assigned to each

Aims: Recurrent pregnancy loss (RPL), defined as three consecutive miscarriages, is a multifaceted problem whose resolution needs a broad approach. In this thesis, epidemiology, immunology, treatment and obstetrical outcomes areexplored. The aims are as follows: To establish the incidence of the diagnosis of RPL in the National Patient Register (NPR) in Sweden from 2003 to 2012 (Paper I). To evalu

Background: Somali women suffer from one of the highest maternal mortality rates in the world. Somalia characterises a specific low-income country situation with a mix of newly urbanized and nomadic culture combined with a frail health care infrastructure set in a post-conflict era. Very little is known about the effects that these contextual factors can have on maternal mortality. Objectives: To

Purpose: To assess the association between cystatin C-derived estimates of kidney function and mortality and acute kidney injury (AKI) in sepsis. Materials and methods: Post-hoc analysis of sepsis patients in the FINNAKI-cohort (n = 802). Primary outcome was 90-day mortality. We measured plasma cystatin C and creatinine at intensive care unit (ICU) admission and estimated glomerular filtration rat

Background: The incidence of atherosclerotic cardiovascular disease increases with levels of low-density lipoprotein cholesterol (LDL-C). Yet, a paradox may exist where lower LDL-C levels at myocardial infarction (MI) are associated with poorer prognoses. Objective: To assess the association between LDL-C levels at MI with risk factor burden and cause-specific outcomes. Methods: Statin-naive patie

Background: Postural orthostatic tachycardia syndrome (POTS) is a heterogeneous condition predominantly affecting autonomic control of the cardiovascular system. Its extensive symptom diversity implies multi-organ involvement that interacts in ways still requiring full exploration. Current understanding of POTS pathophysiology suggests alterations in the renin–angiotensin–aldosterone system as a p

Background: Primary Sclerosing Cholangitis (PSC) is a hepatobiliary disease closely related to ulcerative colitis (UC). In PSC patients, colectomy has been linked to improved prognosis, especially following liver transplantation. This suggests an involvement of the gut-liver axis in PSC etiology. Objective: We aimed to investigate the association between colectomy and the risk of future PSC in an

Despite abundant knowledge about the relationship between inflammation and coronary atherosclerosis, it is still unknown whether systemic inflammation measured as high-sensitivity C-reactive protein (hsCRP) is associated with coronary atherosclerosis in a general population. This study aimed to examine the association between hsCRP and coronary computed tomography angiography (CCTA)-detected coron

In the 30 years since its inception, the field, profession, and practice of logistics and supply chain management have undergone profound business transformation. This study uses shadowing and practice theory to explore the nature of manager competence in logistics and supply chain management. The results suggest that logistics and supply chain managers use business managerial, generic, and behavi

Background/aims: Whereas nonalcoholic fatty liver disease (NAFLD) is a multisystem disease, the association between metabolic dysfunction-associated fatty liver disease (MAFLD) and extra-hepatic diseases is not known. The aim of this cross-sectional study was to compare the prevalence of chronic kidney disease (CKD) in patients with either MAFLD or NAFLD, and then to examine the association betwee

Objectives: To determine the diagnostic performance and optimal protocol of frozen section examination (FSE) in SLNB for cervical cancer. Methods: PubMed, EMBASE, Web of Science, Cochrane Library, Wanfang Data and China National Knowledge Infrastructure were searched from inception to July 30, 2019, for studies concerning SLNB with FSE in cervical cancer. Sensitivity of FSE in detecting SLN metast

This study reports the prevalence and prognostic impact of right bundle branch block (RBBB) and left bundle branch block (LBBB) in the admission electrocardiogram (ECG) of comatose survivors of out-of-hospital cardiac arrest (OHCA). The present study is part of the predefined electrocardiographic substudy of the prospective randomized target temperature management trial, which found no benefit of

Stöd till våldsutsatta kvinnor har historiskt sett varit en uppgift för ideellt arbetande kvinnor på kvinnojourer. De senaste två decennierna har kommunernas ansvar för våldsutsatta kvinnor och barn som bevittnat våld förtydligats. Runt om i landet har kommuner gjort satsningar för att höja kompetensen kring våld i nära relationer och för att förbättra samverkan. I vissa fall har personer med ett

Objective. To study longterm work disability and possible predictors in newly diagnosed patients with primary Sjogren syndrome (pSS). Methods. Because we wanted to include only patients with full work availability potential, eligible patients were aged 18-62 years. Fifty-one patients (mean age 46 yrs, range 18-61 yrs, 50 women) diagnosed with pSS between January 2001 and December 2012 were include

Master Programme in Production and Materials Engineering: Programme sy llabus Master Programme in Production and Materials Engineering Programme code: TAPRR Scope: 120 credits Cycle: Second Approved by: Programme Board M Validity: 2019/2020 Date of approval: 27 March 2019 In addition to the syllabus, general regulations and information for the Faculty of Engineering apply to this programme. 1 Aim

https://www.student.lth.se/fileadmin/lth/english/master/Arkiv/MPRR_Syllabus_19-20.pdf - 2026-05-14

Master's Programme in Production and Materials Engineering Page 1 of 6 PROGRAMME SYLLABUS Master's Programme in Production and Materials Engineering - Programme code: TAPRR - Scope: 120 credits - Cycle: Second - Approved by: Programme Board M - Validity: 2021/2022 - Date of approval: 17 February 2021 In addition to the syllabus, general regulations and information for the Faculty of Engineering ap

https://www.student.lth.se/fileadmin/student/files/Utbildningsplaner_21_22/Master_s_Programme_in_Production_and_Materials_Engineering_21-22.pdf - 2026-05-14

Master's Programme in Sustainable Energy Page 1 of 6 PROGRAMME SYLLABUS Master's Programme in Sustainable Energy - Programme code: TAHET - Scope: 120 credits - Cycle: Second - Approved by: Programme Board M - Validity: 2021/2022 - Date of approval: 17 February 2021 In addition to the syllabus, general regulations and information for the Faculty of Engineering apply to this programme. 1 Aim and out

https://www.student.lth.se/fileadmin/student/files/Utbildningsplaner_21_22/Master_s_Programme_in_Sustainable_Energy_21-22.pdf - 2026-05-14

Master's Programme in Production and Materials Engineering: Programme sy llabus Master's Programme in Production and Materials Engineering Programme code: TAPRR Scope: 120 credits Cycle: Second Approved by: Programme Board M Validity: 2020/2021 Date of approval: 17 February 2020 In addition to the syllabus, general regulations and information for the Faculty of Engineering apply to this programme.

https://www.student.lth.se/fileadmin/lth/english/master/Arkiv/MPRR_Syllabus_20-21.pdf - 2026-05-14