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Artificial intelligence-based versus manual assessment of prostate cancer in the prostate gland : a method comparison study

Aim: To test the feasibility of a fully automated artificial intelligence-based method providing PET measures of prostate cancer (PCa). Methods: A convolutional neural network (CNN) was trained for automated measurements in 18F-choline (FCH) PET/CT scans obtained prior to radical prostatectomy (RP) in 45 patients with newly diagnosed PCa. Automated values were obtained for prostate volume, maximal

Pharmacokinetic modelling and validation of the half-life extension needed to reduce the burden of infusions compared with standard factor VIII

Introduction: Currently, no universally accepted definition of extended half-life (EHL) recombinant FVIII (rFVIII) exists. Identifying the minimum half-life extension ratio required for a reduction in dosing frequency compared with standard rFVIII could enable a more practical approach to decisions around prophylaxis with EHL rFVIII. Aim: To identify the half-life extension ratio required to decre

Outcomes associated with dual antiplatelet therapy after myocardial infarction in patients with aortic stenosis

Background: Acquired loss of the largest von Willebrand factor multimers is a common hemostatic disturbance in patients with aortic valve stenosis (AS), resulting in impaired platelet adhesion and increased bleeding risk. AS is also associated with atherosclerosis and myocardial infarction (MI). Our aim was to study the clinical outcomes associated with AS in MI patients treated with dual antiplat

Incidence and risk factors for thromboembolism and major bleeding in patients with mechanical valve prosthesis : A nationwide population-based study

Risk factors of stroke/thromboembolism (TE) and major bleeding, and incidence of these events in specific age categories in warfarin-treated patients with mechanical heart valves (MHV) are uncertain. Our objective was to calculate event rates in specific age categories and identify risk factors for adverse events. Methods and results We identified 4,810 treatment periods with MHV between January 2

Warfarin treatment and risk of myocardial infarction — A cohort study of patients with atrial fibrillation treated in primary health care

Objective To study the risk of myocardial infarction (MI) in patients with atrial fibrillation (AF) treated in primary health care with warfarin or acetylsalicylic acid (ASA, aspirin). Methods The study population included subjects (n = 12,283) 45 years or older diagnosed with AF who were treated in 75 primary care centres in Sweden between 2001 and 2007. MI was defined as a hospital stay for MI d

Patient-reported Swedish nationwide outcomes of children and adolescents with total colonic aganglionosis

Background: The aim of this study was to evaluate the nationwide outcome of children with total colonic aganglionosis (TCA) during the last 20. years. Methods: This was an observational, cross-sectional study where all patients with TCA, including aganglionosis of 0-50. cm of ileum, born in Sweden 1995-2014 were included. Data were collected from the medical records. Patients>. 4. years old withou

Anxiety in early pregnancy : Prevalence and contributing factors

Antenatal anxiety symptoms are not only a health problem for the expectant mother. Research has found that maternal anxiety may also have an impact on the developing baby. Therefore, it is important to estimate the prevalence of maternal anxiety and associated factors. The current study aims to estimate the prevalence of anxiety symptoms during the first trimester of pregnancy and to identify asso

Concussion incidence and recovery in Swedish elite soccer - prolonged recovery in female players

OBJECTIVES: Sport-related concussions are an increasingly recognized health problem. Soccer is the most popular sport in the world although recent studies on concussion incidence are scarce. Here, a nation-wide prospective study on concussion incidence, symptom severity, risk factors, gender differences and return-to-play after concussion was performed in 51 Swedish elite soccer teams during the 2

Mammographic density is a potential predictive marker of pathological response after neoadjuvant chemotherapy in breast cancer

BACKGROUND: Our aim is to study if mammographic density (MD) prior to neoadjuvant chemotherapy is a predictive factor in accomplishing a pathological complete response (pCR) in neoadjuvant-treated breast cancer patients.METHODS: Data on all neoadjuvant treated breast cancer patients in Southern Sweden (2005-2016) were retrospectively identified, with patient and tumor characteristics retrieved fro

Polish adaptation and validation of the hip disability and osteoarthritis outcome score (HOOS) in osteoarthritis patients undergoing total hip replacement

Background: The Hip disability and Osteoarthritis Outcome Score (HOOS) is a frequently used patient-reported outcome measure (PROM) for assessment of hip disorders and treatment effects following hip surgery. The objective of the study was to translate and adapt the Hip disability and Osteoarthritis Outcome Score (HOOS) into Polish and to investigate the psychometric properties of the HOOS in pati

Orthogonal P-wave morphology, conventional P-wave indices, and the risk of atrial fibrillation in the general population using data from the Finnish Hospital Discharge Register

AIMS: Identifying subjects at high and low risk of atrial fibrillation (AF) is of interest. This study aims to assess the risk of AF associated with electrocardiographic (ECG) markers linked to atrial fibrosis: P-wave prolongation, 3rd-degree interatrial block, P-terminal force in lead V1, and orthogonal P-wave morphology. METHODS AND RESULTS: P-wave parameters were assessed in a representative Fi

Contribution of Established Stroke Risk Factors to the Burden of Stroke in Young Adults

Background and Purpose - As stroke in young adults is assumed to have different etiologies and risk factors than in older populations, the aim of this study was to examine the contribution of established potentially modifiable cardiovascular risk factors to the burden of stroke in young adults. Methods - A German nationwide case-control study based on patients enrolled in the SIFAP1 study (Stroke

Temporal biomarker profiling reveals longitudinal changes in risk of death or myocardial infarction in Non-ST-segment elevation acute coronary syndrome

BACKGROUND: There are conflicting data on whether changes in N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high-sensitivity C-reactive protein (hs-CRP) concentrations between time points (delta NT-proBNP and hs-CRP) are associated with a change in prognosis. METHODS: We measured NT-proBNP and hs-CRP at 3 time points in 1665 patients with non-ST-segment elevation acute coronary syndrome

Measured adiposity in relation to head and neck cancer risk in the European Prospective Investigation into Cancer and Nutrition

BACKGROUND: Emerging evidence from cohort studies indicates that adiposity is associated with greater incidence of head and neck cancer (HNC). However, most studies have used self-reported anthropometry which is prone to error.METHODS: Among 363 094 participants in the European Prospective Investigation into Cancer and Nutrition study (EPIC) with measured anthropometry, there were 837 incident cas

Flygskatt - Ett lämpligt styrmedel?

Titel: Flygskatt – ett lämpligt styrmedel? Nivå: Kandidatuppsats i Service Management, Maj 2006 Författare: Sanja Agbaba, Anne-Sofie Persson, Seda Yazici Institution: Institutionen för Service Management, Lunds Universitet, Campus Helsingborg Handledare: Sumi Park och Mikael Bergmasth Problematisering: Utsläppsproblemen är ett globalt dilemma som berör alla branscher inte bara nationellt men även

Neural networks with personalized training for improved MOLLI T1 mapping

Background: The aim of this study was to develop a method for personalized training of Deep Neural Networks by means of an MRI simulator to improve MOLLI native T1 estimates relative to conventional fitting methods. Methods: The proposed Personalized Training Neural Network (PTNN) for T1 mapping was based on a neural network which was trained with simulated MOLLI signals generated for each individ

The physiological cost of leadership in collective movements

Individuals can gain substantial benefits from collective actions.1,2,3,4,5,6,7 However, collective behaviors introduce new challenges, like coordinating actions, maintaining cohesion, and meeting the needs of different individuals. When making collective movements, leaders are typically thought to gain disproportionate benefits through the choice of more beneficial resources3 and/or earlier acces

Drug–gene interactions and the risk of diabetic microvascular complications : A population-based cohort study

Aims: Drug–gene interactions (DGIs) modify drug response and safety, yet their influence on diabetic microvascular complications remains unclear. This study aimed to elucidate the role of DGIs in these complications. Materials and Methods: Using UK Biobank (UKB) data, we identified medications frequently prescribed to individuals with diabetes and defined DGIs based on the Food and Drug Administra

Rapport vecka31 coss

Rapport vecka 31 (publicerad 2020-08-05) COVID Symptom Study Innehåll Bakgrund 2 Metod 2 Etiskt godkännande 2 Aktuell status 2 10 postnummerområden med högst uppskattad förekomst den 3 augusti . . . . . . . . . . . . . . . 4 10 postnummerområden med lägst uppskattad förekomst den 3 augusti . . . . . . . . . . . . . . . 6 Störst ökning senaste 7 dagarna . . . . . . . . . . . . . . . . . . . . . . .

https://www.covid19app.lu.se/sites/covid19app.lu.se/files/rapport_vecka31_coss.pdf - 2026-05-27

List of publications c ling maj 2019

1 List of publications – Charlotte Ling (690420-4986) 1 LIST OF PUBLICATIONS – CHARLOTTE LING Total of 103 original publications, 18 invited review papers and 8 book chapters since 1999 H-index: 42; Number of citations ~8.500 Original publications 1. Madhusudhan Bysani, Rasmus Agren, Cajsa Davegårdh, Petr Volkov, Tina Rönn, Per Unneberg, Karl Bacos and Charlotte Ling ATAC-seq reveals alterations i

https://www.ludc.lu.se/sites/ludc.lu.se/files/list_of_publications_c_ling_maj_2019.pdf - 2026-05-27