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Background Sarcopenia and poor physical function are common in patients with chronic kidney disease (CKD). Our aim was to investigate the relationships between muscle mass and measured glomerular filtration rate (GFR) and between muscle mass and strength and balance, respectively, in patients with CKD stages 3–5. Methods This is a baseline data analysis of a randomized controlled clinical trial.
Oral squamous cell carcinoma (OSCC) is a major health problem in many parts of the world, and the major causative agents are thought to be the use of alcohol and tobacco. Oncogenic viruses have also been suggested to be involved in OSCC development. This study investigated the prevalence of human papillomaviruses (HPV), herpes simplex virus (HSV) and Epstein-Barr virus (EBV) in 155 OSCC from eight
Background Obesity is linked to cardiovascular diseases and increasingly common in type 1 diabetes mellitus (T1DM) since the introduction of intensified insulin therapy. Our main aim was to explore associations between obesity and depression, anxiety, alexithymia and self-image measures and to control for lifestyle variables in a sample of persons with T1DM. Secondary aims were to explore associat
Health plays an essential role for human and economic development. This thesis consists of four independent empirical papers on health and health care in developing countries. The first paper investigates the relationship between globalization, democracy, and child health in low- and middle-income countries. Using panel data for 70 developing countries between 1970 and 2009 we examine how globaliz
Subarctic ecosystems are predicted to experience the fastest responses to climate change on the planet, with dramatically altered vegetation patterns, frost dynamics and hydrological flow paths. The resulting change in dissolved organic carbon (DOC) export to river systems is poorly known, but reports of rising DOC in northern surface waters have led to widespread speculations on a possible climat
Because several studies have implicated serotonin as a regulator of bone mass, we here explore its potential association on fracture risk and falls, as on bone mineral density (BMD) and muscle strength, in humans. Serum levels of serotonin were analyzed in 950 men (aged 69 to 81 years), participating in the Gothenburg part of the population-based study MrOS Sweden. Men taking selective serotonin r
Background: Fetal cardiovascular magnetic resonance (CMR) imaging may provide a valuable adjunct to fetal echocardiography in the evaluation of congenital cardiovascular pathologies. However, dynamic fetal CMR is difficult due to the lack of direct in-utero cardiac gating. The aim of this study was to investigate the effectiveness of a newly developed Doppler ultrasound (DUS) device in humans for
This thesis explores the external debt situation of developing countries and donor responses in terms of aid composition and debt relief. Primarily, these issues are important for future debt sustainability and therefore for creating beneficial conditions for accelerating growth and reducing poverty. With a focus on domestic factors (e.g. regime type) and exogenous shocks (e.g. terms of trade vol
Capsule Swedish breeding bird species that are predicted to experience a more suitable climate by 2050 are currently increasing in numbers. Aims To test, for a large set of breeding birds, if recent population trends mirror the changes in predicted climatic suitability across the Swedish distribution range, and to test if considering natal dispersal improves the fit of the predictive models. Metho
In experimentally induced myocardial ischemia, mild hypothermia (33-35 degrees C) has a robust cardioprotective effect. Tissue plasminogen activator (t-PA) is a profibrinolytic enzyme that is released from the vascular endothelial cells in response to ischemia and other injurious stimuli. t-PA has also been found to have proinflammatory properties that could contribute to reperfusion injury. We po
The large bloom-forming flagellate Gonyostomum semen has been hypothesized to be inedible to naturally occurring zooplankton due to its large cell size and ejection of long slimy threads (trichocysts) induced by physical stimulation. In a grazing experiment using radiolabelled algae and zooplankton collected from lakes with recurring blooms of G. semen and lakes that rarely experience blooms, we f
The 20q13 region is frequently amplified/overexpressed in breast tumours. However, the nature of this amplification/overexpression is unknown. Here, we investigated genetic variation in five 20q13 amplicon genes (MYBL2, AURKA, ZNF217, STK4 and PTPN1) and its impact on breast cancer (BC) susceptibility and clinical outcome. As a novel finding, four polymorphisms in STK4 (rs6017452, rs7271519) and A
Abstract The main influences on growing conditions in pastures and hayfields are grazing and mowing, which regulate the species struggle for space and resources. If the management ceases, this will contribute to a change of the vegetation. A succession starts where the plant cover gradually will change according to a specific pattern. After some time a few competitive species, previously disfavou
In 2010 there will be a political resolution to ensure that the Swedish society is accessible to all citizens including people with disabilities. For this purpose a national action plan for disability policy "From patient to citizen" (Govt. Bill 1999/2000:79) has been set out with the aim of ensuring that the disability perspective will permeate every sector of society and that the appro
The purpose of this essay is to examine the concept of competence within the social services. More specifically it aims to find out how the social workers themselves look upon their own competence in social investigations concerning children. As the study was based on focus groups the main questions were vague at the beginning and were cleared later on during the group sessions. In three focus gr
The main instrument to combat the abuse of a dominant position within the European Union is Article 82 ECT. It is not intended to prohibit dominance per se, but rather to offer a vehicle for the reaction to actual or potential abuses of undertakings. In order for the Article to come into play the prime requirement is that the undertaking undergoing scrutiny is indeed dominant. Dominance is a relat
This essay is devoted to quite a special form of investment - venture capital. More precisely the purpose is to map out, describe and analyse the most fundamental parts of investment protection in connection with venture capital investments. Venture capital is part of the market of risk capital, which refers to investments occuring on the receipt of, or possibility to receive ownership in a compan
Det finns ett antal olika konkurrensregler inom den europeiska unionens regelverk. Den här uppsatsen behandlar artikel 102 som reglerar missbruk av en dominerande ställning. Varje konkurrensärende måste påbörjas med att en marknad avgränsas. Just då bedömningen avser artikel 102 förfaranden ter sig marknadsdefinitionen än viktigare. Vid avgränsningen av marknaden använder sig kommissionen av kvantWhen applying competition law within Europe, the first stage of the assessment is to define the relevant market. The relevant market is the field of the review, and is not an end in it self. The relevant market contains the information that the assessment is based on. There is a great importance in the assessment of the market, sometimes it is stated that the one who wins the market, wins the case
Syftet med uppsatsen är att skildra äldre studenters studiesituation. Med äldre studenter avses studenter som är mellan 30 och 40 år. Det empiriska underlaget består av både kvantitativt (enkäter) och kvalitativt (intervjuer) material. De frågeställningar som besvaras är: - Varför har respondenterna börjat studera - Påverkas respondenternas identitet av studierna? I så fall hur och på vilket sätt
