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An automated glucose feeding strategy that avoids acetate accumulationin cultivations of Escherichia coli is discussed. We havepreviously described how a probing technique makes it possible todetect and avoid overflow metabolism using a dissolved oxygen sensor.In this paper these ideas are extended with a safety net thatguarantees that aerobic conditions are maintained. The method isgenerally appl

Nuclear structure studies at CST attracted recently increased interest for the results of present activities as well as for the future project FAIR. A broad range of physics phenomena can be addressed by high-resolution in-beam gamma-ray spectroscopy experiments with radioactive beams offered within the Rare Isotopes Spectroscopic INvestigation at GSI (RISING) project. It combined the EUROBALL Ge-

L-DOPA remains the gold-standard treatment for Parkinson's disease but causes motor fluctuations and dyskinesia. Metabotropic glutamate receptor type 5 (mGluR5) has been proposed as a target for antidyskinetic therapies. Here, we evaluate the effects of fenobam, a noncompetitive mGluR5 antagonist already tested in humans, using rodent and nonhuman primate models of L-DOPA-induced dyskinesia. In bo

Energy efficient wireless devices is a trend that has been on the rise the last few years. Energy efficiency properties may fill a function in wireless sensor networks where the devices could run on coin-cell batteries and still last for years. To make sense of the sensor data collected, there is a requirement of accurate time synchronization in the network. This report focuses on investigating if

Social Media Analytic (SMA) is an emerging trend driven by practitioners to access and ana-lyze the increased volumes of user-generated content. The utilization of SMA provides organ-izations with the potential to improve customer insights, digital presence and foster customer relationships. However, despite the positive aspects, acquisition of an emerging technology presents both technical and op

Den digitala utvecklingen har skapat nya förutsättningar för hur individer och or-ganisationer kan interagera, där ett exempel är samskapande (eng. co-creation). Syftet med studien är att undersöka de drivkrafter och känslor som ligger bakom individens beslut till att delta i den specifika samskapandeformen rotation curation tillsammans med organisationer och hur detta skapar mening för individen.The digital evolution has created new ways for individuals and organizations to interact of which one example is co-creation. The purpose of this study is to exa-mine which motives and emotions that underlie an individual’s decision to parti-cipate in the specific form of co-creation called rotation curation together with an an organization and how this creates meaning for the individual. Further,

Ledningsrätt är den rättighet med vilken allmänna ledningar upplåts på andras fastigheter. När det finns en avvikelse mellan ledningens och ledningsrättens läge kan det innebära både att ledningen saknar upplåtelse och att ledningsrätten inte längre är juridiskt gällande. En genomlysning av denna problematik görs för att optimera ledningsrättsupplåtelser. Att ledningsrätter förlorar sin giltighet

Friction modelling is a delicate problem which poses several challenges to control engineers. This work focuses on two recent models which describe friction with nonlinear dynamical systems: The Lugre model, and the model of Bliman & Sorine. Comparisons are made concerning friction phenomena captured, computational issues, identification of model parameters and behaviour at zero-crossings of t

Due to the industry 4.0 paradigm shift, manufacturing and pro-duction industries are focusing on Predictive maintenance (PdM) to increase production efficiency and maintenance strategies. Also, adopting data-driven approaches to implement PdM as a result of increased data usage and exchange. However, facing technical and non-technical challenges. Previous studies majorly concentrated on technologi

This paper looks at how China’s domestic development discourse creates and governs realities of objects, and subject. Using the works of Xi Jinping, the thesis uses the methods of governmentality by Mitchel Dean to analyze the data from the four analytical tools of epistheme, visibility, technical aspect, and identity to look at how the subject is positioned within collective mentalities, status o

Polycystic ovarian syndrome (PCOS) is the most common hormonal condition affecting around 1 in 10 women. Mostly quantitative research has been made on PCOS and patients’ experiences with health care encounters and qualitative studies are deemed vital to portray more nuanced overviews of experiences from patient perspectives. The purpose with this study is to investigate patients’ own experiences w

The main objective of this research study is to investigate how today’s leaders experience remote leadership, thus the following research question is examined: How does a leader make sense of remote leadership? The concept of remote leadership is investigated from a leader perspective using a qualitative method, interviewing 11 remote leaders in the private sector. The following categories have em

Acute myeloid leukemia (AML) is a highly malignant disease of myeloid cell line. AML is the most frequent adult leukemia with inadequate treatment possibility. The protein phosphatases are critical regulators of cell signaling, and deregulation of protein phosphatases always contribute to cell transformation. Although many studies established a relationship between protein phosphatases and leukemi

The Philippines is a unique case to study national identity as it’s a post-colonial, highly Americanized country constituted by quantities of ethnic groups. Filipino identity emerged from the revolution against Spanish colonization and developed as an anti-colonial movement along with its struggles for independence. However, after independence, the Philippines has been facing a dilemma that, on on

The androgen receptor is a key transcription factor contributing to the development of all stages of prostate cancer (PCa). In addition, other transcription factors have been associated with poor prognosis in PCa, amongst which c-Myc (MYC) is a well-established oncogene in many other cancers. We have previously reported that the AR promotes glycolysis and anabolic metabolism; many of these metabol