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Organometallic analogs of chloroquine (CQ) are of interest as drug candidates that may be able to overcome the widespread chloroquine resistance developed by malaria parasites. Two new chromium arene CQ-analogs: [η(6)-N-(7-chloroquinolin-4-yl)-N'-(2-dimethylamino-methylbenzyl)-ethane-1,2-diamine]tricarbonylchromium 4 and [η(6)-N-(7-chloroquinolin-4-yl)-N'-(2-dimethylaminobenzyl)-ethane-1,2-diamine

In this paper, we consider both algebraic crossed products of commutative complex algebras A with the integers under an automorphism of A, and Banach algebra crossed products of commutative C (*)-algebras A with the integers under an automorphism of A. We investigate, in particular, connections between algebraic properties of these crossed products and topological properties of naturally associate

Laminar burning velocities of acetone + air mixtures at initial gas mixture temperatures of 298, 318, 338 and 358 K are reported. Non-stretched flames were stabilized on a perforated plate burner at 1 atm, and laminar burning velocities were determined using the heat flux method, at conditions where the net heat loss from the flame to the burner is zero. The overall accuracy of the burning velocit

Imaging and inverse scattering of seismic reflection data can be formulated in terms of a certain class of Fourier integral operators. We present an approximation and discretization of such operators following a multiscale approach, based on wave packets as the quanta for representing seismic data. One of the key ingredients in our approach is the coupling of dyadic parabolic decomposition and pro

This text deals with a problem concerning processes of the productive power of knowledge. We draw on so called poststructural theories challenging the classical image of thought – as hinged upon a representational logic identifying entities in a rigid sense – when formulating a problem concerning the gap between knowledge and the object of knowledge. More specifically we are looking at this proble

ABSTRACT Radioimmunotherapy (RIT) consists of using monoclonal antibodies (mAbs) recognizing tumor-selective antigens, as carriers of cytotoxic radionuclides to tumor tissue. RIT has been effective in lymphoma but less successful in solid tumors. mAbs slowly diffuse from the vasculature into and through solid tumors, resulting in slow, limited accretion of antibodies. The outcome is a low tumor-to

Kultursemiotiken per se analyserar mötet mellan kulturer. Begrepp som ego-kultur, extrakultur och icke-kultur är centrala i undersökningar som syftar till att blottlägga den självbild en kultur gör av sig själv i mötet med en annan. Dessa begrepp har paralleller på individnivå med de personliga pronomina i språket. I den uppsats jag ämnar presentera kommer jag därför att koncentrera mig på en disk

Popular Abstract in Swedish Projektet har for avsikt att vardera den elektriska overledningen mellan hjartats formak och hur forsamring av denna overledning bidrar till uppkomsten av attackvis pakommande formaks- flimmer. Studierna har anvant sig av ekg- registreringar fran kroppsytan, registreringar fran hjartats insida, anatomiska dissektionsstudier och djurexperiment. Slutsatser 1. OfiltreratThe aim of this thesis was to evaluate the role of interatrial conduction defects in the genesis of lone paroxysmal atrial fibrillation (AF) using combined approach of non-invasive signal-averaged P-wave ECG, invasive electrophysiological (EP) studies, anatomical studies and animal experiments. Non-filtered signal-averaged P-wave ECG revealed irregularities in orthogonal P-wave morphology and the

Invasive exotic plant species effects on soil biota and processes in their new range can promote or counteract invasions via changed plant–soil feedback interactions to themselves or to native plant species. Recent meta-analyses reveale that soil influenced by native and exotic plant species is affecting growth and performance of natives more strongly than exotics. However, the question is how uni

Objective The NORAM (Nonrenal Wegener's Granulomatosis Treated Alternatively with Methotrexate [MTX]) trial demonstrated that MTX can replace cyclophosphamide (CYC) as remission-inducing treatment for patients with newly diagnosed early systemic antineutrophil cytoplasmic antibodyassociated vasculitis. Duration of relapse-free survival was longer among CYC-treated patients than among MTX-treated p

Endophytic bacteria often have beneficial effects on their host plants that can be exploited for bioremediation applications but, according to the literature, only 0.001-1% of all endophytic microbes should be cultivable. This study compared the cultivated endophytic communities of the roots and shoots of Cucurbita pepo with the total endophytic communities as determined by cultivation-dependent t

Given a topological dynamical system Sigma = (X, sigma), where X is a compact Hausdorff space and a a homeomorphism of X, we introduce the Banach *-algebra crossed product l(1) (E) most naturally associated with Sigma and initiate its study. It has a richer structure than its well investigated C*-envelope, as becomes evident from the possible existence of non-self-adjoint closed ideals. We link it

The universally recognised action spectrum for the UV-induced conversion of 7-dehydrocholesterol to previtamin D3 in human skin was published in 1982, and indicates a maximum at about 297 nm with essentially no production above 315 nm. This work represents a milestone in research on vitamin D, but limitations in the original data should be recognised. Various findings have arisen in recent years w

Purpose: This study evaluated postoperative complications of percutaneous nephrolithotomy (PCNL) and the influence of selected factors on the risk of complications using the Clinical Research Office of the Endourological Society (CROES) PCNL Global Study database. Patients and Methods: The CROES PCNL Global Study collected prospective data for consecutive patients who were treated with PCNL at cen

In a preliminary study aimed at outlining the organization of affective categories in Romanian, several cases were identified where Romanians made use of two or more competing linguistic terms applied to what appeared to be the same conceptual configuration . One such case is taken into consideration in this 5-study follow-up investigation, whose purpose was to obtain empirical data for establishi