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A β-decay study of Cu77 has been performed at the ISOLDE mass separator with the aim to deduce its β-decay properties and to obtain spectroscopic information on Zn77. Neutron-rich copper isotopes were produced by means of proton- or neutron-induced fission reactions on U238. After the production, Cu77 was selectively laser ionized, mass separated, and sent to different detection systems where β-γ

Dog polymorphonuclear leukocyte cathepsin G was isolated from a granule extract using a two-step procedure including affinity chromatography on aTrasylol-Sepharose gel and ion-exchange chromatography on a CM 52 column. 22 of the first 24 N-terminal amino acids were determined and showed 83% and 71% identity to those of human and rat cathepsin G, respectively. Total amino-acid composition demonstra

BACKGROUND: The importance of genetic factors in the etiology of Hodgkin lymphoma (HL) has been suggested by family and population studies. However, the spectrum of malignancies associated with common genetic etiology and the effects of gender and age on familial risk have not been established.METHODS: Diagnoses of lymphoproliferative malignancies were compared in 15,799 first-degree relatives of

Introduction: Case–control analyses have shown BARD1 variants to be associated with up to >2-fold increase in risk of breast cancer, and potentially greater risk of triple negative breast cancer. BARD1 is included in several gene sequencing panels currently marketed for the prediction of risk of cancer, however there are no gene-specific guidelines for the classification of BARD1 variants. We pres

Reversible phosphorylation is an important regulatory mechanism. Regulation of protein phosphorylation in β-cells has been extensively investigated, but less is known about protein dephosphorylation. To understand the role of protein dephosphorylation in β-cells and type 2 diabetes (T2D), we first examined mRNA expression of the type 2C family (PP2C) of protein phosphatases in islets from T2D dono

Instituting (Athens, 2021)What could processes of self-organizing and collective making look like in the current landscape? In what ways might they affect public processes of social improvisation? How might such forms of “instituting” give rise to other forms of institutions? Inviting theoretical as well as practical approaches, this edition of the New Alphabet School studies “instituting” as an i

Purpose: To study the phenotype in two families with genetically identified autosomal dominant retinitis pigmentosa (adRP) focusing on macular structure and function. Methods: Clinical data were collected at the Department of Ophthalmology, Lund University, Sweden, for affected and unaffected family members from two pedigrees with adRP. Examinations included optical coherence tomography (OCT), ful

Müllerian mimicry among Neotropical Heliconiini butterflies is an excellent example of natural selection, associated with the diversification of a large continental-scale radiation. Some of the processes driving the evolution of mimicry rings are likely to generate incongruent phylogenetic signals across the assemblage, and thus pose a challenge for systematics. We use a data set of 22 mitochondri

Expanded CAG repeats lead to debilitating neurodegenerative disorders characterized by aggregation of proteins with expanded polyglutamine (polyQ) tracts. The mechanism of aggregation involves primary and secondary nucleation steps. We show how a noncanonical member of the DNAJ-chaperone family, DNAJB6, inhibits the conversion of soluble polyQ peptides into amyloid fibrils, in particular by suppre

Background: GEOMAGIA50.v3 is a comprehensive online database providing access to published paleomagnetic, rock magnetic, and chronological data from a variety of materials that record Earth's magnetic field over the past 50 ka. Findings: Since its original release in 2006, the structure and function of the database have been updated and a significant number of data have been added. Notable modific

Popular Abstract in Swedish Denna studie har gått ut på att relatera litogeo- kemin (= kemin i bergarter) kring Stollbergs järn- och sulfidmalmsfält i Bergslagen till mineralogi och geologisk utveckling. Bergarterna kring Stollberg, liksom kring nästan alla andra järn- och sulfidmalmer (Cu, Pb, Zn) i Bergslagen, utgörs av vulkaniska bildningar. De vulkaniska bergarterna och tillhörande malmer bilThe Paleoproterozoic Fe-Pb-Zn-Mn(-Ag) Stollberg deposit is situated in the Bergslagen region of south-central Sweden. 6.65 Mt of sphalerite, galena and manganiferous skarn magnetite ore occur as disseminations and semi-massive to massive ore bodies hosted by volcanogenic sediments and carbonate rocks. Field relations, mineralogy and geochemistry suggest that the felsic volcanic rocks at Stoll- be

When referring to non-present entities, speakers and signers can select from a range of different strategies to create expressions that range from extremely concise to highly elaborate. This design of referring expressions is based partly on the availability of contextual information that can aid addressee understanding. In the small signing community of Providence Island, signers' heavy reliance

This consensus statement is the product of the Second International Think Tank on Athlete Mental Health, held on the initiative of the International Society of Sport Psychology. The purposes of the Think Tank were to engage international sport psychology societies and organisations in a discussion about athlete mental health as embedded in an Olympic/Paralympic cycle, and to develop practical reco

BACKGROUND: Prostate-specific antigen (PSA) screening and concomitant treatment can be implemented in several ways. The authors investigated how the net benefit of PSA screening varies between common practice versus “good practice.”. METHODS: Microsimulation screening analysis (MISCAN) was used to evaluate the effect on quality-adjusted life-years (QALYs) if 4 recommendations were followed: limite

Short-chain fatty acids (SCFAs), e.g. acetic acid, propionic acid and butyric acid, generated through colonic fermentation of dietary fibers, have been shown to reach the systemic circulation at micromolar concentrations. Moreover, SCFAs have been conferred anti-obesity properties in both animal models and human subjects. Branched SCFAs (BSCFAs), e.g., isobutyric and isovaleric acid, are generated

Objective: To redesign the current assembly process of the Ektorp Sofa from IKEA in order to improve cycle times, quality levels and to reduce, if possible, costs associated with manufacturing, production times and materials. IKEA wants to increase either the productivity or the quality standard of the Ektorp Sofa by simplifying the processes involved in the construc-tion of the sofa and modernizi