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Cancer incidence, mortality, and survival in Eastern Libya : updated report from the Benghazi Cancer Registry

PURPOSE: Despite the increasing burden of cancer occurred over recent years in the African continent, epidemiologic data from Northern Africa area have been so far sparse or absent. We present most recently available data from the Benghazi Cancer Registry concerning cancer incidence and mortality as well as the most comprehensive survival data set so far generated for cases diagnosed during 2003 t

Multivariable flexible modelling for estimating complete, smoothed life tables for sub-national populations

BACKGROUND: The methods currently available to estimate age- and sex-specific mortality rates for sub-populations are subject to a number of important limitations. We propose two alternative multivariable approaches: a relational model and a Poisson model both using restricted cubic splines.METHODS: We evaluated a flexible Poisson and flexible relational model against the Elandt-Johnson approach i

Global surveillance of cancer survival 1995-2009 : analysis of individual data for 25,676,887 patients from 279 population-based registries in 67 countries (CONCORD-2)

BACKGROUND: Worldwide data for cancer survival are scarce. We aimed to initiate worldwide surveillance of cancer survival by central analysis of population-based registry data, as a metric of the effectiveness of health systems, and to inform global policy on cancer control.METHODS: Individual tumour records were submitted by 279 population-based cancer registries in 67 countries for 25·7 million

Offering informed choice about breast screening

Over the last few years, there has been growing international concern about the risk of overdiagnosis in breast screening and about how to communicate this to women. There has also been an increasing policy drive to provide people with information to enable them to make an informed choice about screening. In response to this, a novel approach to developing the information about cancer screening ha

The “Discovery” of White‐Collar Crime: The Legacy of Edwin Sutherland

This chapter examines the very beginning of the criminology of white-collar and corporate crime by focusing on Edwin Sutherland and his "discovery" of the concept of white-collar crime. Sutherland's contributions to the criminology of white-collar crime, beginning with his 1939 American Sociological Society presidential address and culminating with the publication of his book White Collar Crime, c

Can Kings Create Towns that Thrive? The long-term implications of new town foundations

We examine the long-term effects of a series of Swedish towns founded by the Crown during the early modern period. Their advantage over rural parishes consisted in having monopoly rights to trade with the local hinterland. Since the optimum sites were occupied by medieval towns, the Crown could only aim for second-rate locations. Using difference-in-difference combined with Propensity Score Matchi

Performance values - an artistic research perspective on music performance anxiety in classical music

Music performance anxiety (MPA) has been studied mainly within the field of psychology and has been defined as a sub-type of social anxiety. Musicians suffering from MPA are commonly referred to individual psychological treatment, but the condition is not yet researched from an artistic perspective. The hypothesis put forward in this article is that the issues concerning MPA are part of a complex

The Element of Play in Interpretation and Classical Piano Performance

“The stage is a playground, it’s not a serious place where you have to be at your best, ... it should be a playground.” Nir Ben Gal, choreographerDuring my years of study, and later as a performing artist, performance was never discussed conceptually and questions regarding audience interaction and stage fright were seldom raised. Further, musicians suffering from stage fright are most often refer

A catalog of genetic loci associated with kidney function from analyses of a million individuals

Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic complications. Through trans-ancestry meta-analysis of genome-wide association studies of estimated glomerular filtration rate (eGFR) and independent replication (n = 1,046,070), we identified 264 associated loci (166 new). Of these, 147 were likely to be relevant for kidney function on the basis of associat