Recension av Tarje Emberland & Matthew Kott, Himmers Norge – Nordmenn i det storgermanske prosjekt.

Extracellular High Mobility Group Box 1 (HMGB1) has been associated with acute and chronic inflammatory conditions. However, little is known about HMGB1 in necrotizing bacterial infections. We hypothesized that the local HMGB1 response is excessive in severe soft tissue infections (STIs), which are characterized by necrosis and hyperinflammation. To explore this, tissue biopsies were collected fro

We propose a generalized approach to decoupling shading from visibility sampling in graphics pipelines, which we call decoupled sampling. Decoupled sampling enables stochastic supersampling of motion and defocus blur at reduced shading cost, as well as controllable or adaptive shading rates which trade off shading quality for performance. It can be thought of as a generalization of multisample ant

This study examined age differences in phasic heart rate in response to neutral, negative and positive pictures. Heart rate changes and subjective ratings were analyzed in 22 middle-aged (40-55 years) and 30 older (56-78 years) participants. The effects of valence on the HR pattern across time were similar to that obtained by Bradley and co-workers. Conversely to previous studies, we did not repor

Academic developers (ADs) often participate in the implementation of programs or reforms within higher education. Sometimes they agree with these and sometimes they disagree. This paper discusses possible agentic positions during an authentic policy implementation, i.e. the National Qualification Framework within a Norwegian university. Through reflexive interpretation, and by applying concepts f

Popular Abstract in Swedish Neuroblastom är den vanligaste solida tumören, utanför hjärnan, hos små barn och finns nästan inte alls hos vuxna. Varje år insjuknar mellan femton och tjugo barn i Sverige, de flesta före två års ålder. Överlevnaden har ökat de senaste tjugo åren men är fortfarande på låga nivåer för de mer aggressiva formerna. Neuroblastom uppstår i det sympatiska nervsystemet. DärförIn this thesis, the main focus has been on the childhood cancer neuroblastoma, one of the most common and lethal childhood tumours. Neuroblastoma has througout the years continued to be a clinical and biological enigma. Our first focus was on one of the most important biological risk factors in neuroblastoma -- amplification of the oncogene MYCN in the tumour cells. Because amplified MYCN typical

For the first time the direct electron transfer of an enzyme - cellobiose dehydrogenase, CDH - has been coupled with the hexokinase catalyzed competition for glucose in a sensor for ATP. To enhance the signal output for ATP, pyruvate kinase was coimmobilized to recycle ADP by the phosphoenolpyruvate driven reaction. The new sensor overcomes the limit of 1:1 stoichiometry of the sequential or compe

During the last decade, several screening programs for pharmaceuticals at Swedish wastewater treatment plants (WWTPs) have been conducted by research institutes, county councils, and wastewater treatment companies. In this study, influent and effluent concentrations compiled from these screening programs were used to assess the occurrence and reduction of non-antibiotic pharmaceuticals for human u

Popular Abstract in Swedish Alzheimers sjukdom är den vanligaste orsaken till uppkomsten av demens. Detta tillstånd innebär att delar av hjärnan skrumpnar på ett karakteristiskt vis, när nervceller går under. Den drabbade brukar först märka svårigheter med korttidsminnet, för att senare drabbas av språksvårigheter, räknesvårigheter, svårigheter med rumslig uppfattning och svårigheter att veta hur Alzheimer’s disease (AD), the most common cause of dementia, is a growing concern. As the life expectancy increases across the globe, the number of affected people is estimated to reach 100 million by 2050. Efforts to develop effective treatments for humans have mostly been based on the assumption that a faulty homeostasis of beta amyloid (Aβ) is the triggering or the driving factor behind this co

The properties of two-component fermionic quantum systems in two dimensions, such as they nowadays may be realized with cold atoms in traps, are studied within the pairing model adapted from nuclear physics. We compare the results with those of a full numerical diagonalization of the many-body Hamiltonian. The chemical potential differences, excitation energies and angular momentum spectra show th

The elliptic, v(2), triangular, v(3), and quadrangular, v(4), azimuthal anisotropic flow coefficients are measured for unidentified charged particles, pions, and (anti-)protons in Pb-Pb collisions at root S-NN = 2.76 TeV with the ALICE detector at the Large Hadron Collider. Results obtained with the event plane and four-particle cumulant methods are reported for the pseudo-rapidity range vertical

The average charge states of Pb-188 and No-252,No-254 ions in dilute helium gas were measured at the gas-filled recoil separator TASCA. Hydrogen gas was also used as a filling gas for measurements of the average charge state of No-254. Helium and hydrogen gases at pressures from 0.2 mbar to 2.0 mbar were used. A strong dependence of the average charge state on the pressure of the filling gases was

Difference between sexes in parasitism is a common phenomenon among birds, which may be related to differences between males and females in their investment into immune functions or as a consequence of differential exposure to parasites. Because life-history strategies change sex specifically during the annual cycle, immunological responses of the host aiming to reduce the impact of parasites may

The behaviour of building occupants before the purposive movement towards an exit, known as the pre-evacuation behaviour, can have a strong impact on the total time required to leave a building in case of fire emergency as well as on the number of casualties and deaths. The pre-evacuation time can be simulated within computational models using different approaches. This work introduces a new model

Sverige har en vision om ”netto-noll” utsläpp av växthusgaser till 2050 och är på god väg att nå utsatta delmål för utsläppsreduktioner till 2020. Klimatfrågan är dock långsiktig och det under klimatkonventionen antagna 2-gradersmålet innebär utsläppsåtaganden som sträcker sig till år 2050 och bortom. En långsiktigt effektiv klimatpolitik ska därför utvärderas både efter vilka långsiktiga utveck