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Targeted re-sequencing of F8, F9 and VWF : Characterization of Ion Torrent data and clinical implications for mutation screening

Mutations are not identified in ~5% of hemophilia A and 10-35% of type 1 VWD patients. The bleeding tendency also varies among patients carrying the same causative mutation, potentially indicating variants in additional genes modifying the phenotype that cannot be identified by routine single-gene analysis. The F8, F9 and VWF genes were analyzed in parallel using an AmpliSeq strategy and Ion Torre

Effects of a Daytime Nap on Primed and Repeated Remote Associates Tests and Relations with Divergent Creativity

The effect of napping versus wakefulness was studied on primed and repeated Remote Associate Tests (RATs) and on divergent creativity tests. The participants were 42 students from the USA, studying international courses at a Swedish university. The hypotheses for the RATs were (1), when the correct answers were primed before the nap, the RAT should be solved better for those who entered REM sleep,

Future physics opportunities for high-density QCD at the LHC with heavy-ion and proton beams

The future opportunities for high-density QCD studies with ion and proton beams at the LHC are presented. Four major scientific goals are identified: the characterisation of the macroscopic long wavelength Quark-Gluon Plasma (QGP) properties with unprecedented precision, the investigation of the microscopic parton dynamics underlying QGP properties, the development of a unified picture of particle

PYTHIA version 7-0.0 - a proof-of-concept version

This document describes the first proof-of-concept version of the PYTHIA7 program. PYTHIA7 is a complete re-write of the PYTHIA program in C++. It is mainly intended to be a replacement for the `Lund' family of event generators, but is also a framework with a structure suitable for implementing any event generator model. In this document, the structure of the program is presented both from the use

Total cross sections and event properties from real to virtual photons

A model for total cross sections with virtual photons is presented. In particular γ*p and γ*γ* cross sections are considered. Our approach extends on a model for photoproduction, where the total cross section is subdivided into three distinct event classes: direct, VMD and anomalous. With increasing photon virtuality, the latter two decrease in importance. Instead Deep Inelastic Scattering dominat

W production in an improved parton-shower approach

In the description of the production properties of gauge bosons (W±, Z0, γ*) at colliders, the lowest-order graph normally is not sufficient. The contributions of higher orders can be introduced either by an explicit order-by-order matrix-element calculation, by a resummation procedure or by a parton-shower algorithm. Each approach has its advantages and disadvantages. We here introduce a method t

Soft-particle spectra as a probe of interconnection effects in hadronic W+W- events

Cross-talk between the W+ and W- sources of hadron production at LEP2 offers a hope to learn about basic properties of QCD, but at the same time threatens high-precision measurements of the W boson mass. Directly visible effects are not expected to be large, however. It is, therefore, important to develop methods to measure the level of interconnection in the data - 'connectometers'. In this artic

New and old jet clustering algorithms for electron-positron events

Over the years, many jet clustering algorithms have been proposed for the analysis of hadronic final states in e+e- annihilations. These have somewhat different emphasis and are therefore more or less suited for various applications. We here review some of the most used and compare them from a theoretical and experimental point of view.

Production mechanisms of charm hadrons in the string model

In the hadroproduction of charm in the context of string fragmentation, the pull of a beam remnant at the other end of a string may give a charm hadron more energy than the perturbatively produced charm quark. The collapse of a low-mass string to a single hadron is the extreme case in this direction, and gives rise to asymmetries between charm and anticharm hadron spectra. We study these phenomena

Modeling Bose-Einstein correlations at LEP-2

We present new algorithms for simulating Bose–Einstein correlations among final-state bosons in an event generator. The algorithms are all based on introducing Bose–Einstein correlations as a shift of final-state momenta among identical bosons, and differ only in the way energy and momentum conservation is ensured. The benefits and shortcomings of this approach, that may be viewed as a local rewei

A scenario for high-energy γγ interactions

A real photon has a complicated nature, whereby it may remain unresolved or fluctuate into a vector meson or a perturbative qq̄ pair. In γγ events, this gives three by three combinations of the nature of the two incoming photons, and thus six distinct event classes. The properties of these classes are partly constrained by the choices already made in our related γp model. It is therefore possible

Parton distributions of the virtual photon

We propose a generic ansatz for the extension of parton distributions of the real photon to those of the virtual photon. Alternatives and approximations are studied that allow closed-form parametrizations.