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Introduction: Individuals with type 2 diabetes (T2D) are at high risk of experiencing atherosclerotic cardiovascular disease (ASCVD), which is associated with morbidity, mortality and healthcare resource utilisation. Clinical guidelines recommend the use of glucose-lowering medications with cardiovascular benefits in individuals with T2D and cardiovascular disease, but there is evidence that this
In this piece, I investigate how material strategies of commemoration takes part in the recategorization of public space. I look especially at how commemorative vehicles such as toponymic signs, public art and architectural design, play a role in the territorialisation of a specific public place by establishing associations to a new spatial type. This can, for example, include the transformation o
INTRODUCTION: Whether melancholia is a distinct syndrome has long been debated. One aspect of a valid syndrome is whether it allows for determination of a prognosis. The aim of this study is to investigate the course of melancholic depression versus non-melancholic depression with a focus on: (i) time to and probability of recovery from the first depressive episode, (ii) time to and risk of the fi
INTRODUCTION: The risk for brain injury manifested as cerebral palsy is higher in very preterm born children than in term. Prenatal administration of magnesium sulfate (MgSO4 ) has been shown to be neuroprotective and reduces the proportion of very preterm born children later diagnosed with cerebral palsy. A Swedish national clinical practice guideline was implemented in March 2020, stipulating th
BackgroundComplement activation in atypical hemolytic uremic syndrome (aHUS), C3 glomerulonephropathy (C3G) and immune complex-mediated membranoproliferative glomerulonephritis (IC-MPGN) may be associated with rare genetic variants. Here we describe gene variants in the Swedish and Norwegian populations.MethodsPatients with these diagnoses (N=141) were referred for genetic screening. Sanger or nex
When two putatively cryptic species meet in nature, hybrid zone analysis can be used to estimate the extent of gene flow between them. Two recently recognized cryptic species of banded newt (genus Ommatotriton) are suspected to meet in parapatry in Anatolia, but a formal hybrid zone analysis has never been conducted. We sample populations throughout the range, with a focus on the supposed contac
Species with wide-range distributions usually display high genetic variation. This variation can be partly explained by historical lineages that were temporally isolated from each other and are back into secondary reproductive contact, and partly by local adaptations. The smooth newt ( Lissotriton vulgaris) is one of the most widely distributed amphibians species across Eurasia and forms a specie
This paper discusses the morpho-syntax of phrasal proper names likeDeutsche Bahn ‘German Railway’ and Norske Skog ‘Norwegian Forest’ in Germanand Norwegian. As regards determiner elements, there are three types of phrasalproper names in German: some proper names do not have a definite article, some do,and yet others exhibit a possessive. Depending on the syntactic context, the first twotypes patteThis paper discusses the morpho-syntax of phrasal proper names like Deutsche Bahn ‘German Railway’ and Norske Skog ‘Norwegian Forest’ in German and Norwegian. As regards determiner elements, there are three types of phrasal proper names in German: some proper names do not have a definite article, some do, and yet others exhibit a possessive. Depending on the syntactic context, the first two types
Introduction and hypothesisThe mid-urethral sling (MUS) has been used for more than 30 years to cure stress urinary incontinence. The objective of this study was to assess whether surgical technique affects the outcome after more than ten years, regarding dyspareunia and pelvic pain.MethodsIn this longitudinal cohort study we used the Swedish National Quality Register of Gynecological Surgery to i
In recent years the list of disorders affecting amino acid synthesis has grown rapidly. Not only the number of defects has increased, but also the associated clinical phenotypes have expanded spectacular, the latter mainly due to the advances of next-generation sequencing diagnostics. An important reason for the contribution of NGS in the diagnosis of amino acid synthesis disorders is the fact tha
In both the US and EU, policymakers and government agencies are acknowledging theimportance of having access to repair options, particularly for vulnerable product users who depend on their products. As such, repair can play an important role as a resource for resilience, but research is missing. We propose that repair can act as a resource for resilience. A comprehensive, structured way to unders
Two decades into the young history of e-participation research, we aim to take stock of the state of this field in the light of three developments that we argue have substantial implications for research on electronic participation:(1) dissolving boundaries between online and offline spheres of political participation;(2) academic isolation of e-participation research from other research fields re
The incorporation of machine learning methods into proteomics workflows improves the identification of disease-relevant biomarkers and biological pathways. However, machine learning models, such as deep neural networks, typically suffer from lack of interpretability. Here, we present a deep learning approach to combine biological pathway analysis and biomarker identification to increase the interp
Finding alternative and sustainable ways to produce, store and convert energy is key for reducing fossil fuel-based CO2 emissions. In this transformation, hydrogen for energy storage and hydrogen-powered fuel cells for energy conversion can play important roles. However, storage of hydrogen itself is difficult and the concept of reversible liquid organic hydrogen carriers (LOHCs) has been proposed
