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Hybridarbete har blivit en alltmer etablerad arbetsform i arbetslivet och kan innebära ökad flexibilitet och autonomi. Samtidigt kan arbetsformen bidra till att gränsen mellan arbete och privatliv blir mer otydlig, särskilt när arbetet inte längre är bundet till en specifik fysisk arbetsplats. Möjligheten att arbeta på distans kan även bidra till att anställda arbetar trots sjukdom vilket kan påve
Many consumers say they want to shop more sustainably. But most retail websites do not make that easy. Walk through a typical online furniture store, and you will find sustainability information buried in product specifications or tucked away behind a separate filter tab. This happens right when you are already trying to balance price, looks, and whether the thing will actually fit in your living
Large language models (LLMs) have demonstrated exceptional capabilities in complex mathematical reasoning; however, their massive parameter scales impose prohibitive computational costs, limiting their deployment in resource constrained or local environments. To address these challenges, this thesis investigates advanced knowledge distillation methodologies to enhance the mathematical problem-solv
Abstract Introduction: Pneumatic tube system transportation produces particles in protein-based drugs. Background: Different methods have been used to simulate the conditions of pneumatic tube system transportation, and have shown clear correlations to particle formation. Aim(s): The aim of this work is to determine how particle formation and particle size in silicone-free and silicone oil syri
The Stochastic Alpha Beta Rho (SABR) stochastic volatility model is widely used to price European options, but the lack of an exact closed-form solution leaves practitioners choosing between an analytical asymptotic approximation that loses accuracy in certain cases, and grid-based numerical solvers that must be rerun for every parameter set. This thesis investigates the application of a parametri
Since the Russian invasion of Ukraine in 2014, the EU and NATO have strengthened resilience, preparedness, and critical infrastructure policies in response to evolving transboundary threats. However, cascading climate risks, defined as cross-border and cross-sectoral impacts intensified by climate change, have the potential to be insufficiently understood and integrated into EU and NATO frameworks
Peptider är korta kedjor uppbyggda av aminosyror. De senaste åren har peptidläkemedel ökat i popularitet. Speciellt har de så kallade GLP-1 läkemedlen, som Ozempic, visat sig vara en mycket effektiv behandling för både diabetes och övervikt. Den huvudsakliga metoden att producera peptider, fast-fas-peptid syntes (solid phase peptide synthesis, SPPS), utvecklades under 1960-talet och bygger på stegThe most prevalent method of peptide production, solid-phase peptide synthesis (SPPS), generates large amounts of hazardous solvent waste, typically DMF. This waste, combined with the use of the insidious PFAS chemical TFA for side chain PG removal and final resin cleavage, has prompted research into PFAS-free and aqueous solid-phase peptide synthesis (ASPPS) of linear peptides. With the growth of
Oats are common ingredients in many food products. They are valued for their nutritional composition and functional properties. At the same time, oat-based products can develop off-flavours during processing. Lipid oxidation is one important cause of this problem. Aldehydes such as hexanal and nonanal are especially relevant because they can give rancid, grassy, and stale notes. In this project, s
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous group of lymphomas in terms of molecular profile and clinical outcomes, highlighting the need to identify new biomarkers to stratify patients. In this thesis, the protein expression of BCL2, PLK1, MYC and p53 was evaluated in a DLBCL-cohort using multiplex immunofluorescence (mIF) to investigate correlations between protein expression and su
This report studies fatigue in welded steel structures of a conveyor belt using the finite element method (FEM) together with hand calculations based on nominal stress. Three methods were used to evaluate stress at critical locations, the nominal stress method, the hot-spot method, and the effective notch stress method. Detailed FEM models were created where weld geometry and critical stress conce
Ett problem med parkeringsapplikationer är att användare ofta glömmer att avsluta aktiva parkeringssessioner, vilket leder till överbetalning. Denna uppsats designar och utvärderar automatisk avslutning av parkering på ett sätt som minskar överbetalning samtidigt som användarnas tillit och kontroll bevaras, samt utvärderar resultatet. Projektet resulterade i en testapplikation för iOS med en automA problem with parking applications is that users often forget to end active parking sessions, which leads to overpayment. This thesis designs and implements automatic parking termination in a way that reduces overpayment, while preserving user trust and control, as well as evaluating the results. The project resulted in an iOS test application with an automatic termination feature called AutoStop
Avgassystem i Saab Navals ubåtar har under lång tid haft en liknande design. Nya avgassystem följer samma designfilosofi som föregående ubåtar, vilket har resulterat i en låg nivå av teknisk utveckling. Detta har väckt ett intresse inom företaget att undersöka om en mer signifikant designförändring skulle kunna introduceras för framtida ubåtsklasser. Designförändringen som har utvärderats i dettaThe exhaust systems of Saab Naval’s submarines have long maintained a similar design. New exhaust systems have utilised the design philosophy of preceding submarines, resulting in a low level of technical evolution. This has sparked interest within the company to examine whether a more significant design change could be introduced for future submarine classes. The design change evaluated in this
Små förändringar i en skruvs form kan göra stor skillnad för hur plast bearbetas. I detta examensarbete har en metod utvecklats för att designa effektivare skruvar som både ökar produktivitet och minskar energianvändningen. I många tillverkningsprocesser används så kallade extruderskruvar för att smälta och transportera plast. Dessa finns i allt från förpackningsmaskiner till industriproduktion, This thesis presents the development of a structured framework for extrusion screw design based on geometrical parameters, with the aim of improving understanding and supporting design decisions in industrial extrusion processes. The work was carried out in collaboration with Tetra Pak and focuses on the extrusion system used in injection compression molding of Tetra Top lids. An initial numerica
Tekniska utvecklingar och nya produkter i hemmet leder till att allt fler robotar, högtalare, datorer och sladdar ska samspela med befintliga möbler i våra rum. Ett examensarbete vid LTH tog fram ett koncept för att frigöra golvet från sladdar och lämna vägen fri för städning. Sladdar är en ofrånkomlig del av vår vardag, de blir fler, sprider ut sig och är sällan estetiskt tilltalande. Ett populäThis thesis presents the development of a prototype for a concealed power strip integrated into the underside of a sofa. The aim is to improve accessibility to electrical outlets while maintaining a clean and unobtrusive appearance in the living environment. The solution is designed to both hide cables and allow convenient access to power when seated, while ensuring sufficient ground clearance for
Små förändringar i en skruvs form kan göra stor skillnad för hur plast bearbetas. I detta examensarbete har en metod utvecklats för att designa effektivare skruvar som både ökar produktivitet och minskar energianvändningen. I många tillverkningsprocesser används så kallade extruderskruvar för att smälta och transportera plast. Dessa finns i allt från förpackningsmaskiner till industriproduktion, This thesis presents the development of a structured framework for extrusion screw design based on geometrical parameters, with the aim of improving understanding and supporting design decisions in industrial extrusion processes. The work was carried out in collaboration with Tetra Pak and focuses on the extrusion system used in injection compression molding of Tetra Top lids. An initial numerica
Background: Knowledge is increasing about TSC-Associated Neuropsychiatric Disorders (TAND), but little is known about the potentially confounding effects of intellectual ability (IA) on the rates of TAND across age, sex, and genotype. We evaluated TAND in (a) children vs. adults, (b) males vs. females, and (c) TSC1 vs. TSC2 mutations, after stratification for levels of IA, in a large, internationa
This non-interventional post-authorisation safety study (PASS) assessed the long-term safety of everolimus in patients with tuberous sclerosis complex (TSC) who participated in the TuberOus SClerosis registry to increase disease Awareness (TOSCA) clinical study and received everolimus for the licensed indications in the European Union. The rate of adverse events (AEs), AEs that led to dose adjustm
Artificial intelligence is increasingly used in hiring, raising concerns about how applicants perceive these systems. While prior work on algorithmic fairness has emphasized technical bias mitigation, little is known about how avatar identity cues influence applicants' justice attributions in an interview context. We conducted a crowdsourcing study with 215 participants who completed an interview
PURPOSE: To respond to the psychological needs of adolescent and young adult (AYA) cancer survivors, we developed and evaluated a theoretically grounded online intervention to teach adaptive coping skills to promote resilience in early survivorship: 'Recapture Life'. This qualitative study aimed to evaluate the process of implementing Recapture Life into community organisations, after having been
Background: Children and adolescents with autism spectrum disorder (ASD) are generally more sedentary and engage less in physical activity (PA) than their peers. Despite increasing evidence of benefits, practical guidance on implementing adapted PA programs in real-world settings remains limited. This study aimed to document iterative adaptations, implementation processes, and participant experie
